214 resultados para indische Tempel


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traie iberṭragen ois der Gemore Giṭin fon Lipman Lešṭšinski

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u.a.: Einreichung des Berliner Programms an die Buchhandlung Hermann; Indische Sagen von Adolf Holtzmann 1854; Pseudonym "C. Placidus";

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in ein und zwanzig Kanzelvorträgen, gehalten im Neuen Israelitischen Tempel zu Hamburg von Gotthold Salomon

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in neunzehn Kanzelvorträgen, gehalten im Neuen Israelitischen Tempel zu Hamburg von Gotthold Salomon

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in sechsundzwanzig Kanzelvorträgen gehalten im Neuen Israelitischen Tempel zu Hamburg von Gotthold Salomon

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Aus der Sammlung des Leo Baeck Institute, digitalisiert in Kooperation mit dem Center for Jewish History, NY

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Aus der Sammlung des Leo Baeck Institute, digitalisiert in Kooperation mit dem Center for Jewish History, NY

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The tissue distributions and physiological properties of a variety of cloned voltage-gated potassium channel genes have been characterized extensively, yet relatively little is known about the mechanisms controlling expression of these genes. Here, we report studies on the regulation of Kv1.1 expressed endogenously in the C6 glioma cell line. We demonstrate that elevation of intracellular cAMP leads to the accelerated degradation of Kv1.1 RNA. The cAMP-induced decrease in Kv1.1 RNA is followed by a decrease in Kv1.1 protein and a decrease in the whole cell sustained K+ current amplitude. Dendrotoxin-I, a relatively specific blocker of Kv1.1, blocks 96% of the sustained K+ current in glioma cells, causing a shift in the resting membrane potential from −40 mV to −7 mV. These data suggest that expression of Kv1.1 contributes to setting the resting membrane potential in undifferentiated glioma cells. We therefore suggest that receptor-mediated elevation of cAMP reduces outward K+ current density by acting at the translational level to destabilize Kv1.1 RNA, an additional mechanism for regulating potassium channel gene expression.

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Publisher's no: Edition Breitkopf Nr. 1634.

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"De mededeelingen, die vóór 1892 van het Koloniaal museum zijn uitgegaan, komen alle voor in het Tijdschrift van nijverheid. De verkorte inhoud der jaarverslagen en kleine berichten van het museum worden bij voortduring gepubliceerd in datzelfde maandblad, alsmede in het weekblad De Indische Mercuur."-no. 52, p. 182, foot-note.

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Cover title.

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Title varies slightly.