Evaluation of episodic and seasonal emission control for transportation in Illinois /

"December 19, 2001."

Evaluation of methodology for determining truck vehicle miles traveled in Illinois /

"July 2002."

Evaluation of episodic and seasonal emission control for transportation in Illinois /

"January 2002."

Feasibility of a systematic approach to water quality management in Illinois : annual report of stream/lake classification project /

Pbk.

Performance of resurfacing of JRCP and CRCP on the Illinois interstate highway system /

"Project IHR-517, Illinois Cooperative Highway Research Program."

Programs for management of water withdrawals in Illinois : final report /

"Project: 88/062."

State of Illinois analysis of fair housing impediments as submitted to the U.S. Department of Housing and Urban Development for Jim Edgar, Governor /

Final report by University of Illinois at Urbana-Champaign, the Building Research Council [by] Kate Brown, Len Heumann, Karen Winter-Nelson. Prepared for the State of Illinois and the Illinois Housing Development Authority.

Status and functions of isolated wetlands in Illinois /

"IP733038"--Page 2 of cover.

Toward the development of a county employment projection system for the State of Illinois : a report to the Illinois Environmental Protection Agency, Division of Air Pollution Control /

Cover title: Towards the development of a county employment projection system for the state of Illinois.

A survey of joint-labor management cooperation committees in unionized private enterprises in the state of Illinois, 1979 /

Prepared for submission to the U.S. Department of Labor in accordance with Contract NP8AC009 issued by the National Center for Productivity and Quality of Working Life.

Higher education and the concept of community /

"October 21, 1993."

The Alumni quarterly and fortnightly notes of the University of Illinois

Mode of access: Internet.

Principal soil association areas of Illinois.

Mimeographed.

Studies of Protein-Protein and Protein-Water Interactions by Small Angle X-Ray Scattering, Terahertz Spectroscopy, ASMOS, And Computer Simulation

The protein folding problem has been one of the most challenging subjects in biological physics due to its complexity. Energy landscape theory based on statistical mechanics provides a thermodynamic interpretation of the protein folding process. We have been working to answer fundamental questions about protein-protein and protein-water interactions, which are very important for describing the energy landscape surface of proteins correctly. At first, we present a new method for computing protein-protein interaction potentials of solvated proteins directly from SAXS data. An ensemble of proteins was modeled by Metropolis Monte Carlo and Molecular Dynamics simulations, and the global X-ray scattering of the whole model ensemble was computed at each snapshot of the simulation. The interaction potential model was optimized and iterated by a Levenberg-Marquardt algorithm. Secondly, we report that terahertz spectroscopy directly probes hydration dynamics around proteins and determines the size of the dynamical hydration shell. We also present the sequence and pH-dependence of the hydration shell and the effect of the hydrophobicity. On the other hand, kinetic terahertz absorption (KITA) spectroscopy is introduced to study the refolding kinetics of ubiquitin and its mutants. KITA results are compared to small angle X-ray scattering, tryptophan fluorescence, and circular dichroism results. We propose that KITA monitors the rearrangement of hydrogen bonding during secondary structure formation. Finally, we present development of the automated single molecule operating system (ASMOS) for a high throughput single molecule detector, which levitates a single protein molecule in a 10 µm diameter droplet by the laser guidance. I also have performed supporting calculations and simulations with my own program codes.

Exact Solution of Bayes and Minimax Change-Detection Problems

The challenge of detecting a change in the distribution of data is a sequential decision problem that is relevant to many engineering solutions, including quality control and machine and process monitoring. This dissertation develops techniques for exact solution of change-detection problems with discrete time and discrete observations. Change-detection problems are classified as Bayes or minimax based on the availability of information on the change-time distribution. A Bayes optimal solution uses prior information about the distribution of the change time to minimize the expected cost, whereas a minimax optimal solution minimizes the cost under the worst-case change-time distribution. Both types of problems are addressed. The most important result of the dissertation is the development of a polynomial-time algorithm for the solution of important classes of Markov Bayes change-detection problems. Existing techniques for epsilon-exact solution of partially observable Markov decision processes have complexity exponential in the number of observation symbols. A new algorithm, called constellation induction, exploits the concavity and Lipschitz continuity of the value function, and has complexity polynomial in the number of observation symbols. It is shown that change-detection problems with a geometric change-time distribution and identically- and independently-distributed observations before and after the change are solvable in polynomial time. Also, change-detection problems on hidden Markov models with a fixed number of recurrent states are solvable in polynomial time. A detailed implementation and analysis of the constellation-induction algorithm are provided. Exact solution methods are also established for several types of minimax change-detection problems. Finite-horizon problems with arbitrary observation distributions are modeled as extensive-form games and solved using linear programs. Infinite-horizon problems with linear penalty for detection delay and identically- and independently-distributed observations can be solved in polynomial time via epsilon-optimal parameterization of a cumulative-sum procedure. Finally, the properties of policies for change-detection problems are described and analyzed. Simple classes of formal languages are shown to be sufficient for epsilon-exact solution of change-detection problems, and methods for finding minimally sized policy representations are described.