Toscana virus in Spain

Toscana virus (TOSV, Phlebovirus, family Bunyaviridae) infection is one of the most prevalent arboviruses in Spain. Within the objectives of a multidisciplinary network, a study on the epidemiology of TOSV was conducted in Granada, in southern Spain. The overall seroprevalence rate was 24.9%, significantly increasing with age. TOSV was detected in 3 of 103 sandfly pools by viral culture or reverse transcription-polymerase chain reaction from a region of the L gene. Nucleotide sequence homology was 99%-100% in TOSV from vectors and patients and 80%-81% compared to the Italian strain ISS Phl.3. Sequencing of the N gene of TOSV isolates from patients and vectors indicated 87%-88% and 100% homology at the nucleotide and amino acid levels, respectively, compared to the Italian strain. These findings demonstrate the circulation of at least 2 different lineages of TOSV in the Mediterranean basin, the Italian lineage and the Spanish lineage.

Genetic diversity of Toscana virus

Distribution of Toscana virus (TOSV) is evolving with climate change, and pathogenicity may be higher in nonexposed populations outside areas of current prevalence (Mediterranean Basin). To characterize genetic diversity of TOSV, we determined the coding sequences of isolates from Spain and France. TOSV is more diverse than other well-studied phleboviruses (e.g.,Rift Valley fever virus).

Lymphocytic choriomeningitis virus-associated meningitis, southern Spain.

Lymphocytic choriomeningitis virus (LCMV) was detected in 2 patients with acute meningitis in southern Spain within a 3-year period. Although the prevalence of LCMV infection was low (2 [1.3%] of 159 meningitis patients), it represents 2.9% of all pathogens detected. LCMV is a noteworthy agent of neurologic illness in immunocompetent persons.

Jose María Paras, criador, padre y valetudinario

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Sermón que en la festividad con que celebró la cofradía de nuestra señora Santa María de Guadalupe de la ciudad de Querétaro, la aparición prodigiosa de su santisima patrona el día 14 de diciembre de 1816

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Glorias de Querétaro en la fundación y admirables progresos de la muy I. y ven. congregación eclesiástica de presbíteros seculares de María Santísima de Guadalupe de México...

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Cervantes y sus obras ; artículos por d. José Ma. Asensio

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La novela en el teatro : Cartas del señor D. José M. de Pereda con aclaraciones y comentarios de Luis Ruíz y Contreras

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Pensamientos filosóficos del Canciller Bacon; tr. por José MaríaTorner.

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Protesta del Episcopado Mexicano, dirigida a los Exmos. S. S. Regentes, Generales D. Juan N. Almonte y D. José Mariano Salas, con motivo delas circulares espedidas en 9 de noviembre y 16 de diciembre de 1863.

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Las siete palabras de María, pequeño poema bíblico en ocho cantos

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Theologica de inmaculata conneptione B.V. Maríae dissertatio auctore Josepho María Diez de Sollano.

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