Serotype/serogroup-specific antibiotic non-susceptibility of invasive and non-invasive Streptococcus pneumoniae, Switzerland, 2004 to 2014.

Concurrent analysis of antibiotic resistance of colonising and invasive Streptococcus pneumoniae gives a more accurate picture than looking at either of them separately. Therefore, we analysed 2,129 non-invasive and 10,996 invasive pneumococcal isolates from Switzerland from 2004 to 2014, which spans the time before and after the introduction of the heptavalent (PCV7) and 13-valent (PCV13) conjugated pneumococcal polysaccharide vaccines. Serotype/serogroup information was linked with all antibiotic resistance profiles. During the study period, the proportion of non-susceptible non-invasive and invasive isolates significantly decreased for penicillin, ceftriaxone, erythromycin and trimethoprim/sulfamethoxazole (TMP-SMX). This was most apparent in non-invasive isolates from study subjects younger than five years (penicillin (p = 0.006), erythromycin (p = 0.01) and TMP-SMX (p = 0.002)). Resistant serotypes/serogroups included in PCV7 and/or PCV13 decreased and were replaced by non-PCV13 serotypes (6C and 15B/C). Serotype/serogroup-specific antibiotic resistance rates were comparable between invasive and non-invasive isolates. Adjusted odds ratios of serotype/serogroup-specific penicillin resistance were significantly higher in the west of Switzerland for serotype 6B (1.8; 95% confidence interval (CI): 1.4-4.8), 9V (3.4; 95% CI: 2.0-5.7), 14 (5.3; 95% CI: 3.8-7.5), 19A (2.2; 95% CI: 1.6-3.1) and 19F (3.1; 95% CI: 2.1-4.6), probably due to variations in the antibiotic consumption.

The conquest of death /

Mode of access: Internet.

Causes of death of anesthesiologists from the chloroform era /

"Grant no. R805473-01."

Mars in the house of death;

Mode of access: Internet.

Handbook of death : mechanisms, causes and certification /

Includes index.

Russian dance of death,

Diary of a teacher in Ukraine during the Russian revolution, relating mainly the tribulations of the Dutch settlers. cf. Introd.

United Nations Convention on the Declaration of Death of Missing Persons; a commentary

Mode of access: Internet.

Third Review Conference of the Treaty on the Non-Proliferation of Nuclear Weapons [microform] : hearing before the subcommittees on Arms Control, International Security, and Science and on International Economic Policy and Trade of the Committee on Foreign Affairs, House of Representatives, Ninety-ninth Congress, first session, August 1, 1985.

CIS Microfiche Accession Numbers: CIS 86 H381-49

Relative risk of death for ejected occupants in fatal traffic accidents. Technical report.

Mode of access: Internet.

Manual of the international list of causes of death : based on the 3rd decennial revision of the International Commission, Paris, Octobe 11 to 15, 1920.

At head of title: Department of Commerce and Labor. Bureau of the Census. W.M. Steuart, director.

A note on the non-existence of multivalue A-stable methods of order greater than two /

Bibliography: leaf 3.

The Triumph of Death

Pieter Bruegel the Elder; 3 ft. 10 1/16 in.x 5 ft. 3 25/32 in.; oil on panel