The articles which all that belong to the private meeting instituted at Harvard College, 1719, assent unto, January 10, 1723

This one-page document contains the handwritten laws of an unnamed Harvard College religious society. The document is dated January 10, 1723 and includes the signatures of twenty-six students in the Harvard Classes of 1724 through 1728.

Some account of a paper call'd the Telltale, begun in colledge Sept 1721

The small leather-bound volume holds two sections, a manuscript student periodical, and written tête-bêche, an exchange on smallpox inoculation followed by notes on the rules and activities of a Harvard College student club. The volume begins with thirteen numbered manuscript issues, written in one hand, of the Tell-Tale running from September 9, 1721 to November 1, 1721. Prefaced, "This paper was entitl'd the Telltale or Criticisms on the Conversation & Beheavour of Scholars to promote right reasoning & good manner," the work is modeled after literary periodicals of the time, including the "Spectator," and is considered the oldest student publication at Harvard. The periodical appears to have circulated in manuscript form. The content varies in format and includes letters between Telltale and correspondents, short essays, and advertisements. Topics discussed include conversation, detraction, and flattery. While not specifically about Harvard it does provide some information about the College including evidence of various student activities and organizations at Harvard in the 1720s. The entry explaining the rules of the Telltale Club is heavily faded and nearly illegible. The Telltale records multiple dreams, which are populated by various characters, such as “beautiful” Kate, two “learned Physicians” debating inoculation, “four Fellows” “pushing and shoving one another,” and a “person of a very Dark & swarthy complexion in a Slovenly Dress with 7 patches & 5 sparks on his Face.”

Commonplace book of Benjamin Penhallow, 1721-1724

This leather-bound volume contains excerpts copied by Benjamin Penhallow from books he read while he was a student at Harvard in the 1720s. The volume contains extracts from two texts: Johanis Henrici Alstedii's (John Henry Alsted / Johann Heinrich Alsted) Geometria Domini, and the anonymous text "The Legacy of a dying Father; bequeath'd to his Beloved Children, or Sundry Directions in Order unto a well Regulated Conversation," from 1724 (originally published in 1693-4). The last page of text in the volume contains the hymn "The Sacred Content of Praise" first published in 1734, and added after Penhallow's death.

Miscellaneous letters addressed to Delia Tudor,

One letter, signature illegible; one letter from William C. Workman regarding a note of introduction from a Lady Percival; one letter in French from a Mr. Chauriteau in Havana.

Atividade antibacteriana de sementes de açaí (Euterpe oleracea Mart.)

O presente trabalho teve como objetivo avaliar a atividade antibacteriana de um extrato aquoso de sementes de açaí (Euterpe oleracea Mart.), proveniente do Brasil, em isolados clínicos. O extrato revelou atividade antibacteriana em todos os isolados clínicos testados com a exceção de Escherichia coli e de Klebsiella pneumoniae. Os melhores valores de CMIs (concentrações mínimas inibitórias) foram observados para Staphylococcus aureus resistente à meticilina (MRSA) (0,25 mg/mL), Staphylococcus aureus sensível à meticilina (MSSA), Enterococcus faecalis e Streptococcus agalactiae com um valor de 0,5 mg/mL. O extrato testado parece ser uma opção a explorar no combate de bactérias resistentes.

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

Kinetochores assemble on distinct 'centrochromatin' containing the histone H3 variant CENP-A and interspersed nucleosomes dimethylated on H3K4 (H3K4me2). Little is known about how the chromatin environment at active centromeres governs centromeric structure and function. Here, we report that centrochromatin resembles K4-K36 domains found in the body of some actively transcribed housekeeping genes. By tethering the lysine-specific demethylase 1 (LSD1), we specifically depleted H3K4me2, a modification thought to have a role in transcriptional memory, from the kinetochore of a synthetic human artificial chromosome (HAC). H3K4me2 depletion caused kinetochores to suffer a rapid loss of transcription of the underlying α-satellite DNA and to no longer efficiently recruit HJURP, the CENP-A chaperone. Kinetochores depleted of H3K4me2 remained functional in the short term, but were defective in incorporation of CENP-A, and were gradually inactivated. Our data provide a functional link between the centromeric chromatin, α-satellite transcription, maintenance of CENP-A levels and kinetochore stability.

Scio Township and Ann Arbor Township (Mich.) residences and business, ca. 1874

Left to right: Res. of J.T. Sullivan Esq., Sec. 27, Scio Tp., Mich.; Res. of Wm. C. Foster, Sec. 26, Scio Tp. Mich.; Res. of L.C. Risdon, Dealer in Hardware, No. 81 South Main St., Ann Arbor, Mich.; Res. of Dr. D.B. Kellogg, Ann Arbor, Mich.; Ann Arbor, Mich.; Res. of David Mowerson, Sec. 14, Ann Arbor Tp. Mich. Publication information: Chicago, Ill. : Everts & Stewart, 1874

South College

South Wing, also called South College, built in 1849; demolished in 1950. Male person in image. On verso: Evidently the old South Wing of "South College" taken prior to 1871. The view, in the opinion of William C. Hood, who studied the shadows, from the northwest. Wm. Shaw, 11/30/37

Procedures for estimating dry weather pollutant deposition in sewerage systems /

Mode of access: Internet.

Comparison of numerical and physical hydraulic models, Masonboro Inlet, North Carolina : Appendix 1, fixed-bed hydraulic model results /

"June 1977."

Supplementary tests of Masonboro Inlet fixed-bed model : hydraulic model investigation /

"General investigation of tidal inlets; a program of research conducted jointly by U.S. Army Coastal Engineering Research Center, Fort Belvoir, Virginia [and] U.S. Army Engineer Waterways Experiment Station, Vicksburg, Mississippi."

The government of New Hampshire,

"Primary ballots" (2 folded leaves), "Official ballot" (folded leaf), "Map of New Hampshire" (folded leaf), "Chart of New Hampshire government" (folded leaf), "New Hampshire state flag" (plate) in pocket.