Transport of animals between rooms: A little-noted aspect of laboratory procedure that may interfere with memory

This study investigated the effects of transporting animals from the experimental room to the animal facility in between experimental sessions, a procedure routinely employed in experimental research, on long-term social recognition memory. By using the intruder-resident paradigm, independent groups of Wistar rats exposed to a 2-h encounter with an adult intruder were transported from the experimental room to the animal facility either 0.5 or 6h after the encounter. The following day, residents were exposed to a second encounter with either the same or a different (unfamiliar) intruder. Resident`s social and non-social behaviors were carefully scored and subjected to Principal Component Analysis, thus allowing to parcel out variance and relatedness among these behaviors. Resident rats transported 6h after the first encounter exhibited reduced amount of social investigation towards familiar intruders, but an increase of social investigation when exposed to a different intruder as compared to the first encounter. These effects revealed a consistent long-lasting (24h) social recognition memory in rats. In contrast, resident rats transported 0.5 h after the first encounter did not exhibit social recognition memory. These results indicate that this common, little-noted, laboratory procedure disturbs long-term social recognition memory. (C) 2011 Elsevier B.V. All rights reserved.

New and little-known cheilostomatous Bryozoa from the south and southeastern Brazilian continental shelf and slope

The present paper reports on 22 species collected by the Brazilian Program of Living Resources in the Exclusive Economic Zone (REVIZEE). A new genus and species of Cribrilinidae, Corbuliporina crepida n. gen. et sp., is described, along with seventeen other new species: Chaperia brasiliensis n. sp., Amastigia aviculifera n. sp., Isosecuriflustra pinniformis n. sp., Cellaria subtropicalis n. sp., Melicerita brasiliensis n. sp., Arachnopusia haywardi n. sp., Smittina migottoi n. sp., Hippomenella amaralae n. sp., Rogicka joannae n. sp., Malakosaria atlantica n. sp., Turbicellepora winstonae n. sp., Rhynchozoon coalitum n. sp., Stephanollona angusta n. sp., Stephanollona arborescens n. sp., Aulopocella americana n. sp., Conescharellina cookae n. sp. and Conescharellina bocki n. sp. Chorizopora brongniartii (Audouin, 1826) is recorded for the first time in Brazilian waters and a new combination for Rhynchozoon arborescens Canu & Bassler, 1928 is established. New illustrations and taxonomic remarks are included for two little-known species from Brazil, Rogicka scopae (Canu & Bassler, 1928) and Fenestrulina ampla Canu & Bassler, 1928. A compilation of species recorded from deeper waters of the Brazilian coast is included.

XRCC1 haploinsufficiency in mice has little effect on aging, but adversely modifies exposure-dependent susceptibility

Oxidative DNA damage plays a role in disease development and the aging process. A prominent participant in orchestrating the repair of oxidative DNA damage, particularly single-strand breaks, is the scaffold protein XRCC1. A series of chronological and biological aging parameters in XRCC1 heterozygous (HZ) mice were examined. HZ and wild-type (WT) C57BL/6 mice exhibit a similar median lifespan of similar to 26 months and a nearly identical maximal life expectancy of similar to 37 months. However, a number of HZ animals (7 of 92) showed a propensity for abdominal organ rupture, which may stem from developmental abnormalities given the prominent role of XRCC1 in endoderm and mesoderm formation. For other end-points evaluated-weight, fat composition, blood chemistries, condition of major organs, tissues and relevant cell types, behavior, brain volume and function, and chromosome and telomere integrity-HZ mice exhibited by-and-large a normal phenotype. Treatment of animals with the alkylating agent azoxymethane resulted in both liver toxicity and an increased incidence of precancerous lesions in the colon of HZ mice. Our study indicates that XRCC1 haploinsufficiency in mammals has little effect on chronological longevity and many key biological markers of aging in the absence of environmental challenges, but may adversely affect normal animal development or increase disease susceptibility to a relevant genotoxic exposure.

Five Little Monkeys Jumping on the Bed : En litteraturstudie om hur arbete med sång, rim och ramsor kan främja barns utveckling av engelska som främmande språk i grundskolans tidigare år.

Syftet med litteraturstudien är att undersöka hur arbete med sång, rim och ramsor kan främja yngre elevers språkutveckling i engelska som främmande språk. Detta görs genom att fokusera på främjandet av barns språkinlärning, hur lärare bör arbeta med sång, rim och ramsor inom engelska som främmande språk, samt lärares attityder till ett sådant arbetssätt. Arbetet genomfördes som en systematisk litteraturstudie innehållande en bakgrund med relevant teori, samt analys av fem vetenskapliga studier rörande ämnet. Dessa gav möjlighet till en bred bild av området, då länder och perspektiv varierade. Studierna valdes ut genom sökning i databaser efter relevans och tillförlitlighet. I studiernas resultat framgick att majoriteten av tillfrågade lärare och elever var positivt inställda till arbete med sång och ramsor i engelskundervisning, och den språkutveckling dessa metoder innebar. Genom arbete med läraren som förebild motiverades eleverna. Dock fanns en avsaknad av material och kunskap för att kunna genomföra och bedöma undervisning innehållande sång och ramsor. En avsaknad av rim i de studier som analyserats berörs även i studien, likaså en brist på svenska studier. Sammanfattningsvis verkar sång och ramsor enligt de granskade studierna ha ett värde i engelskundervisning. Dock finns det behov av mer forskning och kunskap för att få starkare underlag för användning av dessa metoder i undervisning.

Slavoj Zizek: a little piece of the real

Contents: Introduction : locating Zizek as critical theorist -- 1. On Zizek's expanded notion of ideology -- 2. Western (European) modernity and its discontents -- 3. Lack in the other -- 4. Zizek's ticklish subject -- 5. Does Zizek have a critical social theory of contemporary capitalism? -- 6. Taking sides : what is left in Zizek? (the abyss of freedom?)

Some care, little responsibility? Promoting directors'and managers' legal accountability for Occupational Health and Safety in the workplace

Health and safety at work remains a serious and under-recognised problem in Australia. This paper argues for the importance of increasing the individual responsibility and accountability of senior managers and directors of corporations for the development and maintenance of occupational health and safety (OHS) standards in the workplace. In order to do so, the paper first sets out the range of statutory and general law duties and liabilities to which directors and senior managers are subject, considers to what extent these obligations have relevance in the OHS area and argues for the extension of these duties and liabilities in some circumstances. The paper then goes on to argue for a better legislative model for the legal responsibility of managers and officers, supported by the increased prosecution of individuals in appropriate circumstances, as well as acknowledging the benefits of a broader range of non-legal strategies to improve board level commitment to OHS that will influence corporate compliance overall.

The power of rhythm and words : from little things big things grow

Primary literacy teacher educators need to re-conceptualise the ways in which they work together to model effective interdisciplinary practice. This paper reports on such practice in a team teaching unit for postgraduate students undertaking the Bachelor of Teaching (Primary/Secondary) at Deakin University, Melbourne. The interdisciplinary (Social Education, Language and Music) unit, a first in the Faculty of Education was conceptualised to challenge both lecturer and student (local and international) to 'rethink' their understandings of pedagogy, multi-literacies and teacher preparedness. For the purpose of this paper, the authors reflect on a particular team teaching experience whereby a text (song) was used to teach both the elements of music and literacy pedagogy. It opened up new possibilities for students to engage and participate with each discipline as well as how one area can inform and further deepen the understanding for learners of the other. For example, musical notation and score was used to explain and use the 4 resource model (Luke and Freebody, 1990). The authors contend that crossdisciplinary work cannot be reduced to simple cooperation among disciplines but that primary literacy teacher educators need to develop new conceptual frameworks for learning that will enhance their understandings of pedagogy and assist in preparing teachers in a challenging world.

So much to do, so little time: multicultural practices and Australian school music

In this paper, the authors are concerned with the challenges, dilemmas and choices that teachers face when teaching multicultural music in classrooms in Australia in an already overcrowded curriculum. This paper considers the notion of changing and shifting cultures, looking at how teachers can break out of the familiar paradigms in which they were trained. There will be a consideration of the notion of cultural ownership questioning whose music is to be taught, how is it to be taught, and by whom. A discussion of how music is embedded in the culture that creates it is undertaken in relation to the concepts of authenticity and transmission. The authors contend that the exploration of other cultures enables the making of connections within and without the classroom and beyond the school into the local, national and global arenas. It is our position that teachers should not hesitate to explore other musics and cultures. It is noted that teachers need support to do this which can only enhance both their teaching and the learning of their students even though there is so much to do in so little time.