Norito ryakkai /

On double leaves, oriental style, in case.

Opera omnia : seu trutina medica, chirurgica, pharmaceutico-chymica, [etc.] /

Anteportada.

Uiruson to demokurashii /

Includes translation of speeches by President Wilson.

Katsugo shinan

At head of title: Atamagaki kōtei

Digital Classics Outside the Echo-Chamber : Teaching, Knowledge Exchange and Public Engagement /

The international perspectives on these issues are especially valuable in an increasingly connected, but still institutionally and administratively diverse world. The research addressed in several chapters in this volume includes issues around technical standards bodies like EpiDoc and the TEI, engaging with ways these standards are implemented, documented, taught, used in the process of transcribing and annotating texts, and used to generate publications and as the basis for advanced textual or corpus research. Other chapters focus on various aspects of philological research and content creation, including collaborative or community driven efforts, and the issues surrounding editorial oversight, curation, maintenance and sustainability of these resources. Research into the ancient languages and linguistics, in particular Greek, and the language teaching that is a staple of our discipline, are also discussed in several chapters, in particular for ways in which advanced research methods can lead into language technologies and vice versa and ways in which the skills around teaching can be used for public engagement, and vice versa. A common thread through much of the volume is the importance of open access publication or open source development and distribution of texts, materials, tools and standards, both because of the public good provided by such models (circulating materials often already paid for out of the public purse), and the ability to reach non-standard audiences, those who cannot access rich university libraries or afford expensive print volumes. Linked Open Data is another technology that results in wide and free distribution of structured information both within and outside academic circles, and several chapters present academic work that includes ontologies and RDF, either as a direct research output or as essential part of the communication and knowledge representation. Several chapters focus not on the literary and philological side of classics, but on the study of cultural heritage, archaeology, and the material supports on which original textual and artistic material are engraved or otherwise inscribed, addressing both the capture and analysis of artefacts in both 2D and 3D, the representation of data through archaeological standards, and the importance of sharing information and expertise between the several domains both within and without academia that study, record and conserve ancient objects. Almost without exception, the authors reflect on the issues of interdisciplinarity and collaboration, the relationship between their research practice and teaching and/or communication with a wider public, and the importance of the role of the academic researcher in contemporary society and in the context of cutting edge technologies. How research is communicated in a world of instant- access blogging and 140-character micromessaging, and how our expectations of the media affect not only how we publish but how we conduct our research, are questions about which all scholars need to be aware and self-critical.

Cardiac chymase: pathophysiological role and therapeutic potential of chymase inhibitors

On release from cardiac mast cells, alpha-chymase converts angiotensin I (Ang I) to Ang II. In addition to Ang II formation, alpha-chymase is capable of activating TGF-beta 1 and IL-1 beta, forming endothelins consisting of 31 amino acids, degrading endothelin-1, altering lipid metabolism, and degrading the extracellular matrix. Under physiological conditions the role of chymase in the mast cells of the heart is uncertain. In pathological situations, chymase may be secreted and have important effects on the heart. Thus, in animal models of cardiomyopathy, pressure overload, and myocardial infarction, there are increases in both chymase mRNA levels and chymase activity in the heart. In human diseased heart homogenates, alterations in chymase activity have also been reported. These findings have raised the possibility that inhibition of chymase may have a role in the therapy of cardiac disease. The selective chymase inhibitors developed to date include TY-51076, SUN-C8257, BCEAB, NK320, and TEI-E548. These have yet to be tested in humans, but promising results have been obtained in animal models of myocardial infarction, cardiomyopathy, and tachycardia-induced heart failure. It seems likely that orally active inhibitors of chymase could have a place in the treatment of cardiac diseases where injury-induced mast cell degranulation contributes to the pathology.

Herpetofauna associada à bromélia rupícola, encholirium spectabile, no semiárido brasileiro: revisão da literatura, ecologia das espécies e comportamento de psychosaura agmosticha (squamata: mabuyidae)

Bromeliads are an important microhabitat for the herpetofauna, for being widely used as refuge from predators and their leaf architecture allows humidity maintenance and relatively constant temperature inside, setting a favorable environment for amphibians and reptiles, especially in areas under hydric stress. However, studies addressing this relationship are still incipient and more concentrated in fitotelmatas bromeliad. For non-fitotelmatas rupicolous bromeliads of the gender Encholirium, which develops into rocky outcrops and contains species of semi-arid regions such as the Caatinga, animal-plant relationships are almost unknown. In this context, this study aimed to know the herpetological fauna inhabitant of macambiras bromeliads, Encholirium spectabile, analyzing occupation and use of these bromeliads by different taxa, and the behavioral ecology of the lizard Psychosaura agmosticha, seeking to identify factors associated with this strict relationship in Caatinga. An extensive review of the world literature on the subject “lizards in bromeliads” subsidized this study from the ecological perspective of this association. The field work was carried out at Fazenda Tanques, municipality of Santa Maria / RN, mesoregion of Agreste Potiguar. The observations and/or data collection in daytime and in the evening was conducted monthly during three consecutive days, from January 2011 to August 2012, totaling 450 hour.man of sampling effort. Sixteen species were registered: six lizards (Mabuyidae, Tropiduridae, Gekkonidae and Phyllodactylidae Families), six snakes (Boidae and Dipsadidae Families) and four of amphibians of Hylidae Family. The effect of the forest edge on the distribution of species along the outcrop was significant, with most species found in outcrop edges. Significant difference was found between some pairs of species concerning use of bromeliads, and almost total niche overlap in the use of microhabitat. 62.5% of the species are nocturnal and use these plants for sheltering, breeding and feeding. Regarding the relations between 4 the lizard Psychosaura agmosticha and macambiras bromeliads, behaviors of thermoregulation and foraging in the dry and wet seasons were recorded. Activity periods were concentrated between 7 and 10 am and between 3 and 5 pm in both seasons, showing a clear bimodal pattern. The species basically used the green leaves and there were no significant differences between males and females in the use of bromeliads. Positive associations were found between body temperature and temperatures of bromeliads and air. This species spent 1.95% ± 3.8 of the time moving (PTM) and moved on average 0:36 ± 2.1 seconds per minute (MPM), with significant differences between the wet and dry to PTM, and between the average time of stop and average duration of movements, being considered a sedentary forager. Psychosaura agmosticha, in the study area, is bromelicolous and uses macambiras primarily for thermoregulation and foraging. The results of this study elevate the rupicolous bromeliads Encholirium spectabile as key elements for the maintenance of amphibians and reptiles associated with it, and a clear advantageous association for the conservation of the groups involved.

Coupled symplectic maps as models for subdiffusive processes in disordered Hamiltonian lattices

Acknowledgements One of us (T. B.) acknowledges many interesting discussions on coupled maps with Professor C. Tsallis. We are also grateful to the anonymous referees for their constructive feedback that helped us improve the manuscript and to the HPCS Laboratory of the TEI of Western Greece for providing the computer facilities where all our simulations were performed. C. G. A. was partially supported by the “EPSRC EP/I032606/1” grant of the University of Aberdeen. This research has been co-financed by the European Union (European Social Fund - ESF) and Greek national funds through the Operational Program “Education and Lifelong Learning” of the National Strategic Reference Framework (NSRF) - Research Funding Program: THALES - Investing in knowledge society through the European Social Fund.

Coupled symplectic maps as models for subdiffusive processes in disordered Hamiltonian lattices

Acknowledgements One of us (T. B.) acknowledges many interesting discussions on coupled maps with Professor C. Tsallis. We are also grateful to the anonymous referees for their constructive feedback that helped us improve the manuscript and to the HPCS Laboratory of the TEI of Western Greece for providing the computer facilities where all our simulations were performed. C. G. A. was partially supported by the “EPSRC EP/I032606/1” grant of the University of Aberdeen. This research has been co-financed by the European Union (European Social Fund - ESF) and Greek national funds through the Operational Program “Education and Lifelong Learning” of the National Strategic Reference Framework (NSRF) - Research Funding Program: THALES - Investing in knowledge society through the European Social Fund.

Las puestas comunales de Hemidactylus boavistensis en la isla de Sal (Archipiélago de Cabo Verde)

[ES]De acuerdo con Pough (1973), los requerimientos metabólicos de un saurio de pequeño tamaño determinan que su dieta deba ser básicamente insectívora. El mismo autor añadía que cuando el lagarto sobrepasa un determinado tamaño esa dieta basada en el consumo exclusivo de artrópodos ya no va a permitirle cubrir sus necesidades energéticas básicas y debe, por eso, buscar alternativas. Aunque en términos generales muchas especies se ajustan bastante bien a estas “reglas” ecofisiológicas, en los últimos 25 años han sido numerosos los trabajos publicados en los que se han recogido ejemplos que contravienen las previsiones de ese modelo, especialmente cuando se trata de lagartos que viven en comunidades insulares (Pérez Mellado & Corti, 1999; Cooper & Vitt, 2002; Espinoza et al., 2004).

Adaptación a la alimentación natural de Gallotia simonyi (Sauria, Lacertidae) en cautividad

[ES] El lagarto gigante de El Hierro (Gallotia simonyi) es un lacértido endémico seriamente amenazado de extinción, y objeto de un plan de recuperación que consiste en la cría en cautividad y en la futura reintroducción en un nuevo hábitat. G. simonyi es una especie principalmente herbívora cuya dieta en cautividad no guardaba relación con los alimentos presentes en el área propuesta para la reintroducción. Se ha llevado a cabo una experiencia consistente en cambiar los hábitos alimenticios de un grupo de individuos de G. simonyi mantenidos en cautividad en el Centro de Recuperación del Lagarto Gigante de El Hierro. Se estableció un período de adaptación controlado para comprobar si consumían los elementos vegetales existentes en el área susceptible de ser colonizada.

Liberación experimental de dos lagartos gigantes de El Hierro (Gallotia simonyi) criados en cautividad.

[ES] El lagarto gigante de El Hierro (Gallotia simonyi machadoi: Lacertidae) es un endemismo insular en peligro de extinción. Tan sólo se conoce una población de pocos ejemplares en la isla de El Hierro (Islas Canarias). En 1986 se inició la cría en cautividad con fines conservacionistas, pero la ausencia de criterios para su reintroducción ha provocado que, actualmente, los efectivos en cautividad superen el tamaño estimado de la población silvestre. Con el fin de calibrar la viabilidad de un plan de reintroducción basado en la liberación de lagartos criados en cautividad, dos machos adultos, provistos de radiocollares, fueron liberados en un lugar preseleccionado de la isla, dentro del área de distribución histórica de la especie (La Dehesa).

Los fenotipos y subespecies de Gallotia atlantica

[ES] El lagarto atlántico (Gallotia atlantica), el más pequeño de todos los lacértidos que existen en el archipiélago Canario (López-Jurado, 1991), es probablemente también el más polimórfico. Su enorme plasticidad morfológica se manifiesta especialmente en su tamaño y colorido (López-Jurado y Mateo, 1992), y en caracteres folidóticos como el número de poros femorales, o el de escamas en el collar o en el dorso (Bischoff, 1985; Castroviejo et al., 1985).

Predación de Gallotia simonyi por gatos cimarrones

[ES] El lagarto gigante de El Hierro (Gallotia simonyi machadoi) es uno de los reptiles más cercanos a la extinción en todo el mundo (GROOMBRIDGE, 1993). Se conoce una sola población silvestre de este lacértido herbívoro de gran tamaño (MACHADO, 1985b), endémico de la isla de El Hierro (280 km2, 1500 m, Islas Canarias) y cuyos efectivos numéricos en cuanto a adultos y subadultos se cifraron entre 120 y 150 individuos en el verano de 1995 mediante métodos de marcado y recaptura (PÉREZ-MELLADO et al., 1997).

Biologia reprodutiva e ecologia trófica de Thamnodynastes hypoconia (Serpentes: Dipsadidae) em ambientes úmidos subtemperados do extremo sul brasileiro

O estudo teve como objetivo descrever a biologia reprodutiva e a dieta de populações de Thamnodynastes hypoconia em ambientes úmidos subtemperados do extremo sul brasileiro. Para avaliação da reprodução foram feitas análises macroscópicas das gônadas. Para avaliação da ecologia alimentar foram empregadas análises de conteúdo estomacal e de isótopos estáveis (δ13C e δ15N). Os machos apresentaram maior comprimento rostro-cloacal que as fêmeas e atingiram a maturidade sexual com menor tamanho corporal. O ciclo reprodutivo das fêmeas foi sazonal, com vitelogênese secundária ocorrendo entre o inverno e a primavera. Os machos apresentaram ciclo contínuo. Aparentemente a cópula ocorre entre o final da primavera e o início do verão, quando foram detectados embriões nas fêmeas e a parturição ocorreu no verão. Não houve relação entre o tamanho da ninhada e o tamanho da fêmea, e a frequência reprodutiva de 40% foi considerada relativamente baixa. Todavia, por ser uma espécie dominante em banhados subtemperados do extremo sul do Brasil sua estratégia reprodutiva parece ser eficiente. Dessa forma, o ciclo contínuo dos machos, bem como a viviparidade possam potencializar o deslocamento do pico reprodutivo da população de modo a ajustar-se de acordo com os picos de temperatura do ambiente. A análise de conteúdo estomacal mostrou uma dieta predominantemente anurófaga, exceto por um único lagarto. Hylidae foi a família mais representativa, com predomínio de Hypsiboas pulchellus, seguida de Leptodactylidae, onde Leptodactylus latrans teve maior importância. As análises de isótopos estáveis corroboraram a importância dessas espécies na alimentação da serpente. Apesar de ser uma serpente terrestre, T. hypoconia apresentou assinatura isotópica mais próxima das fontes primárias oriundas do ambiente aquático, o que indica a importância das áreas alagáveis para a subsistência de organismos terrestres de habitats adjacentes.