Solvent-Free Enantioselective Friedländer Condensation with Wet 1,1′-Binaphthalene-2,2′-diamine-Derived Prolinamides as Organocatalysts

Wet unsupported and supported 1,1′-binaphthalene-2,2′-diamine (BINAM) derived prolinamides are efficient organocatalysts under solvent-free conditions at room temperature to perform the synthesis of chiral tacrine analogues in good yields (up to 93%) and excellent enantioselectivies (up to 96%). The Friedländer reaction involved in this process takes place with several cyclohexanone derivatives and 2-aminoaromatic aldehydes, and it is compatible with the presence of either electron-withdrawing or electron-donating groups at the aromatic ring of the 2-aminoaryl aldehyde derivatives used as electrophiles. The reaction can be extended to cyclopentanone derivatives, affording a regioisomeric but separable mixture of products. The use of the wet silica gel supported organocatalyst, under solvent-free conditions, for this process led to the expected product (up to 87% enantiomeric excess), with its reuse being possible at least up to five times.

Effect of water vapour condensation on the radon content in subsurface air in a hypogeal inactive-volcanic environment in Galdar cave, Spain

Fluctuations of trace gas activity as a response to variations in weather and microclimate conditions were monitored over a year in a shallow volcanic cave (Painted Cave, Galdar, Canary Islands, Spain). 222Rn concentration was used due to its greater sensitivity to hygrothermal variations than CO2 concentration. Radon concentration in the cave increases as effective vapour condensation within the porous system of the rock surfaces inside the cave increases due to humidity levels of more than 70%. Condensed water content in pores was assessed and linked to a reduction in the direct passage of trace gases. Fluctuations in radon activity as a response to variations in weather and microclimate conditions were statistically identified by clustering entropy changes on the radon signal and parameterised to predict radon concentration anomalies. This raises important implications for other research fields, including the surveillance of shallow volcanic and seismic activity, preventive conservation of cultural heritage in indoor spaces, indoor air quality control and studies to improve understanding of the role of subterranean terrestrial ecosystems as reservoirs and/or temporary sources of trace gases.

Computer planning for efficient solid waste collection : [a condensation] /

"Condensation of Mathematical Analysis of Solid Waste Collection by David H. Marks and Jon C. Liebman."

A study of solid waste collection systems comparing one-man with multi-man crews : a condensation /

"This condensation (SW-9c. 1)--is based on the Ralph Stone and Company, Inc., report by the same title."

Recherches sur la chaleur développée dans la combustion et dans la condensation des vapours;

Mode of access: Internet.

Economical flue gas desulfurization resulting in valuable fertilizer : supplemental condensation of report /

Supplemental condensation of the author's Valuable fertilizer products from high sulfur coal stack gas.

The Mayflower pilgrims, being a condensation in the original wording and spelling of the story written by Gov. William Bradford of their privations and trials, and the voyage of the Mayflower and settlement at Plymouth in the year 1620.

"This condensation of the first part of Governor William Bradford's History of Plymouth plantation covers the period in the history of the English 'Separatists' sect from 1608-1621."--Pref.

Die condensation des acetons mit alkalien.

Thesis (Ph. D.)--Bonn.

Ueber die condensation aromatischer ketone.

Thesis (doctoral)--

Condensation of vapor as induced by nuclei and ions.

"The contemporaneous variations of the nucleation and the ionization of the atmosphere of Providence, by Lulu B. Joslin": p. 123-154.

Ueber die condensation von isovaleraldehyd mit glutarsaure.

Thesis (doctoral)--

Recherches sur quelques derives du 2, 4-dinitro-1-naphtol et sur les derives d'azonium obtenus par condensation de l'acide [beta]-naphtoquinone-4-sulfonique avec la phenylorthophenylenediamine /

Thesis (doctoral)--Universitate de Geneve, 1897.

Uber die condensation von benzylcyanid mit opiansaure sowie mit...

Thesis (doctoral)--

Recherches sur le produit de condensation de l'aldehyde formiqu...

Thesis (doctoral)--

Ueber condensation von dekamethylendiamin mit aldehyden und ket...

Thesis (doctoral)--