Replication Data Management,needs and solutions: an initial evaluation of conceptual approaches for integrating heterogeneous replication study data

Replication Data Management (RDM) aims at enabling the use of data collections from several iterations of an experiment. However, there are several major challenges to RDM from integrating data models and data from empirical study infrastructures that were not designed to cooperate, e.g., data model variation of local data sources. [Objective] In this paper we analyze RDM needs and evaluate conceptual RDM approaches to support replication researchers. [Method] We adapted the ATAM evaluation process to (a) analyze RDM use cases and needs of empirical replication study research groups and (b) compare three conceptual approaches to address these RDM needs: central data repositories with a fixed data model, heterogeneous local repositories, and an empirical ecosystem. [Results] While the central and local approaches have major issues that are hard to resolve in practice, the empirical ecosystem allows bridging current gaps in RDM from heterogeneous data sources. [Conclusions] The empirical ecosystem approach should be explored in diverse empirical environments.

Proceso metodológico para optimizar la toma de decisiones en el proyecto de envolventes arquitectónicas multicapa = Methodological process for the optimization of the decision making in multilayer building envelope projects

La presente tesis doctoral se enmarca dentro del concepto de la sistematización del conocimiento en arquitectura, más concretamente en el campo de las construcciones arquitectónicas y la toma de decisiones en la fase de proyecto de envolventes arquitectónicas multicapa. Por tanto, el objetivo principal es el establecimiento de las bases para una toma de decisiones informadas durante el proyecto de una envolvente multicapa con el fin de colaborar en su optimización. Del mismo modo que la historia de la arquitectura está relacionada con la historia de la innovación en construcción, la construcción está sujeta a cambios como respuesta a los fracasos anteriores. En base a esto, se identifica la toma de decisiones en la fase de proyecto como el estadio inicial para establecer un punto estratégico de reflexión y de control sobre los procesos constructivos. La presente investigación, conceptualmente, define los parámetros intervinientes en el proyecto de envolventes arquitectónicas multicapa a partir de una clasificación y sistematización de todos los componentes (elementos, unidades y sistemas constructivos) utilizados en las fachadas multicapa. Dicha sistematización se materializa en una hoja matriz de datos en la que, dentro de una organización a modo de árbol, se puede acceder a la consulta de cada componente y de su caracterización. Dicha matriz permite la incorporación futura de cualquier componente o sistema nuevo que aparezca en el mercado, relacionándolo con aquellos con los que comparta ubicación, tipo de material, etc. Con base en esa matriz de datos, se diseña la sistematización de la toma de decisiones en la fase de proyecto de una envolvente arquitectónica, en concreto, en el caso de una fachada. Operativamente, el resultado se presenta como una herramienta que permite al arquitecto o proyectista reflexionar y seleccionar el sistema constructivo más adecuado, al enfrentarse con las distintas decisiones o elecciones posibles. La herramienta se basa en las elecciones iniciales tomadas por el proyectista y se estructura, a continuación y sucesivamente, en distintas aproximaciones, criterios, subcriterios y posibilidades que responden a los distintos avances en la definición del sistema constructivo. Se proponen una serie de fichas operativas de comprobación que informan sobre el estadio de decisión y de definición de proyecto alcanzados en cada caso. Asimismo, el sistema permite la conexión con otros sistemas de revisión de proyectos para fomentar la reflexión sobre la normalización de los riesgos asociados tanto al proprio sistema como a su proceso constructivo y comportamiento futuros. La herramienta proporciona un sistema de ayuda para ser utilizado en el proceso de toma de decisiones en la fase de diseño de una fachada multicapa, minimizando la arbitrariedad y ofreciendo una cualificación previa a la cuantificación que supondrá la elaboración del detalle constructivo y de su medición en las sucesivas fases del proyecto. Al mismo tiempo, la sistematización de dicha toma de decisiones en la fase del proyecto puede constituirse como un sistema de comprobación en las diferentes fases del proceso de decisión proyectual y de definición de la envolvente de un edificio. ABSTRACT The central issue of this doctoral Thesis is founded on the framework of the concept of the systematization of knowledge in architecture, in particular, in respect of the field of building construction and the decision making in the design stage of multilayer building envelope projects. Therefore, the main objective is to establish the bases for knowledgeable decision making during a multilayer building envelope design process, in order to collaborate with its optimization. Just as the history of architecture is connected to the history of innovation in construction, construction itself is subject to changes as a response to previous failures. On this basis, the decisions made during the project design phase are identified as the initial state to establish an strategic point for reflection and control, referred to the constructive processes. Conceptually, this research defines the parameters involving the multilayer building envelope projects, on the basis of a classification and systematization for all the components (elements, constructive units and constructive systems) used in multilayer façades. The mentioned systematization is materialized into a data matrix sheet in which, following a tree‐like organization, the access to every single component and its characterization is possible. The above data matrix allows the future inclusion of any new component or system that may appear in the construction market. That new component or system can be put into a relationship with another, which it shares location, type of material,… with. Based on the data matrix, the systematization of the decision making process for a building envelope design stage is designed, more particularly in the case of a façade. Putting this into practice, it is represented as a tool which allows the architect or the designer, to reflect and to select the appropriate building system when facing the different elections or the different options. The tool is based on the initial elections taken by the designer. Then and successively, it is shaped on the form of different operative steps, criteria, sub‐criteria and possibilities which respond to a different progress in the definition of the building construction system. In order to inform about the stage of the decision and the definition reached by the project in every particular case, a range of operative sheets are proposed. Additionally, the system allows the connection with other reviewing methods for building projects. The aim of this last possibility is to encourage the reflection on standardization of the associated risks to the building system itself and its future performance. The tool provides a helping system to be used during the decision making process for a multilayer façade design. It minimizes the arbitrariness and offers a qualification previous to the quantification that will be done with the development of the construction details and their bill of quantities, that in subsequent project stages will be executed. At the same time, the systematization of the mentioned decision making during the design phase, can be found as a checking system in the different stages of the decision making design process and in the different stages of the building envelope definition.

Evaluation of the PV cell operation temperature in the process of fast switching to open-circuit mode

A procedure for measuring the overheating temperature (ΔT ) of a p-n junction area in the structure of photovoltaic (PV) cells converting laser or solar radiations relative to the ambient temperature has been proposed for the conditions of connecting to an electric load. The basis of the procedure is the measurement of the open-circuit voltage (VO C ) during the initial time period after the fast disconnection of the external resistive load. The simultaneous temperature control on an external heated part of a PV module gives the means for determining the value of VO C at ambient temperature. Comparing it with that measured after switching OFF the load makes the calculation of ΔT possible. Calibration data on the VO C = f(T ) dependences for single-junction AlGaAs/GaAs and triple-junction InGaP/GaAs/Ge PV cells are presented. The temperature dynamics in the PV cells has been determined under flash illumination and during fast commutation of the load. Temperature measurements were taken in two cases: converting continuous laser power by single-junction cells and converting solar power by triple-junction cells operating in the concentrator modules.

PROFESSORAS BEM-SUCEDIDAS SÃO PROFESSORAS REFLEXIVAS?! A prática da reflexividade nas ações pedagógicas de professoras nos anos iniciais de escolaridade

O presente estudo consiste numa pesquisa processual, de natureza qualitativa, expresso na modalidade narrativa. Tem como pressuposto que o papel do professor implica uma tal responsabilidade que resulta em exigência de aperfeiçoamento constante, para que este profissional possa apresentar-se capaz de uma ação pedagógica bem-sucedida. Um professor, assim caracterizado, corresponde ao profissional efetivamente engajado na prática docente, manifestando atitude de reflexão sobre esta mesma prática, não apenas antes, em sua preparação, mas durante o seu desenrolar e mesmo depois desta, procurando extrair da própria ação elementos que ajudem a constantemente melhorá-la. Sob tais aspectos, destaco a prática reflexiva de Professoras do Ensino Fundamental, nos anos iniciais de escolaridade, especialmente relativa a suas ações pedagógicas bem-sucedidas em aulas, que busco enfocar como objeto de estudo e de investigação nesta dissertação. A coleta de dados da pesquisa deu-se por meio de 1) entrevistas semi-estruturadas, 2) relatos orais, 3) observação de aulas e 4) notas de campo. A análise dos dados, a discussão dos resultados e os encaminhamentos possíveis para a formação de professores foram construídos e expressos levando em conta princípios e critérios da Investigação Narrativa. Das conclusões, tecidas à luz do que resulta desta investigação, destacam-se as que são assim enunciadas: a) as Professoras realizam práticas reflexivas de tipos e níveis diferentes, contudo, tais reflexões ocorrem visivelmente atreladas às suas dificuldades e aos seus conflitos didático-pedagógicos, cada qual em seu contexto específico de ação; b) As Professoras conseguem realizar reflexões na sua ação, bem como reflexões sobre a sua ação com aproximações à literatura pedagógica, ainda que com ausência de explicitação de aspectos sociológicos, filosóficos, políticos, antropológicos, epistemológicos, enfim, dos aspectos que conferem maior criticidade e critério à reflexão, ou seja, atributos de reflexividade. Em função disso, ressalto a importância do progresso da escola em consonância com o progresso e a profissionalização do trabalho docente, através da consideração de cada contexto específico num movimento de busca de sentido para o ensino e para a aprendizagem. Nas considerações finais, propugno para o professor reflexivo compromissos evidentes com o futuro, no presente de suas salas de aula, para que possa ter maior capacidade de resposta pedagógica às necessidades educativas dos seus alunos, que se inserem e vivem na complexa sociedade deste século XXI.

PROFESSORAS BEM-SUCEDIDAS SÃO PROFESSORAS REFLEXIVAS?! A prática da reflexividade nas ações pedagógicas de professoras nos anos iniciais de escolaridade

O presente estudo consiste numa pesquisa processual, de natureza qualitativa, expresso na modalidade narrativa. Tem como pressuposto que o papel do professor implica uma tal responsabilidade que resulta em exigência de aperfeiçoamento constante, para que este profissional possa apresentar-se capaz de uma ação pedagógica bem-sucedida. Um professor, assim caracterizado, corresponde ao profissional efetivamente engajado na prática docente, manifestando atitude de reflexão sobre esta mesma prática, não apenas antes, em sua preparação, mas durante o seu desenrolar e mesmo depois desta, procurando extrair da própria ação elementos que ajudem a constantemente melhorá-la. Sob tais aspectos, destaco a prática reflexiva de Professoras do Ensino Fundamental, nos anos iniciais de escolaridade, especialmente relativa a suas ações pedagógicas bem-sucedidas em aulas, que busco enfocar como objeto de estudo e de investigação nesta dissertação. A coleta de dados da pesquisa deu-se por meio de 1) entrevistas semi-estruturadas, 2) relatos orais, 3) observação de aulas e 4) notas de campo. A análise dos dados, a discussão dos resultados e os encaminhamentos possíveis para a formação de professores foram construídos e expressos levando em conta princípios e critérios da Investigação Narrativa. Das conclusões, tecidas à luz do que resulta desta investigação, destacam-se as que são assim enunciadas: a) as Professoras realizam práticas reflexivas de tipos e níveis diferentes, contudo, tais reflexões ocorrem visivelmente atreladas às suas dificuldades e aos seus conflitos didático-pedagógicos, cada qual em seu contexto específico de ação; b) As Professoras conseguem realizar reflexões na sua ação, bem como reflexões sobre a sua ação com aproximações à literatura pedagógica, ainda que com ausência de explicitação de aspectos sociológicos, filosóficos, políticos, antropológicos, epistemológicos, enfim, dos aspectos que conferem maior criticidade e critério à reflexão, ou seja, atributos de reflexividade. Em função disso, ressalto a importância do progresso da escola em consonância com o progresso e a profissionalização do trabalho docente, através da consideração de cada contexto específico num movimento de busca de sentido para o ensino e para a aprendizagem. Nas considerações finais, propugno para o professor reflexivo compromissos evidentes com o futuro, no presente de suas salas de aula, para que possa ter maior capacidade de resposta pedagógica às necessidades educativas dos seus alunos, que se inserem e vivem na complexa sociedade deste século XXI.

Blockade of action potential activity alters initial arborization of thalamic axons within cortical layer 4.

In the formation of connections during the development of the nervous system, it is generally accepted that there is an early phase not requiring neural activity and a later activity-dependent phase. The initial processes of axonal pathfinding and target selection are not thought to require neural activity, whereas the later fine-tuning of connections into their final adult patterns does. We report an apparent exception to this rule in which action potential activity seems to be required very early in development for thalamic axons to form appropriate patterns of terminal arborizations with their ultimate target neurons in layer 4 of the cerebral cortex. Blockade of sodium action potentials during the 2-week fetal period when visual thalamic axons initially grow into the primary visual cortex in cats prevents the normally occurring branching of lateral geniculate nucleus axons within layer 4. This observation implies a role for action-potential activity in cerebral cortical development far earlier than previously suspected, weeks before eye-opening and the onset of the well-known process of activity-dependent reorganization of axonal terminal arbors that leads to the formation of ocular dominance columns.

Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor.

Two endocytic receptors, the low density lipoprotein (LDL) receptor (LDLR) and the LDLR-related protein (LRP), are thought to act in concert in the hepatic uptake of partially metabolized dietary lipoproteins, the chylomicron remnants. We have evaluated the role of these two receptors in the hepatic metabolism of chylomicron remnants in normal mice and in LDLR-deficient [LDLR (-/-)] mice. The rate of chylomicron remnant removal by the liver was normal up to 30 min after intravenous injection of chylomicrons into LDLR (-/-) mice and was unaffected by receptor-associated protein (RAP), a potent inhibitor of ligand binding to LRP. In contrast, endocytosis of the remnants by the hepatocytes, measured by their accumulation in the endosomal fraction and by the rate of hydrolysis of component cholesteryl esters, was dramatically reduced in the absence of the LDLR. Coadministration of RAP prevented the continuing hepatic removal of chylomicron remnants in LDL (-/-) mice after 30 min, consistent with blockade of the slow endocytosis by a RAP-sensitive process. Taken together with previous studies, our results are consistent with a model in which the initial hepatic removal of chylomicron remnants is primarily mediated by mechanisms that do not include LDLR or LRP, possibly involving glycosaminoglycan-bound hepatic lipase and apolipoprotein E. After the remnants bind to these alternative sites on the hepatocyte surface, endocytosis is predominantly mediated by the LDLR and also by a slower and less efficient backup process that is RAP sensitive and therefore most likely involves LRP.

Mathematical modeling of drying process of unripe banana slices

Unripe banana flour (UBF) production employs bananas not submitted to maturation process, is an interesting alternative to minimize the fruit loss reduction related to inappropriate handling or fast ripening. The UBF is considered as a functional ingredient improving glycemic and plasma insulin levels in blood, have also shown efficacy on the control of satiety, insulin resistance. The aim of this work was to study the drying process of unripe banana slabs (Musa cavendishii, Nanicão) developing a transient drying model through mathematical modeling with simultaneous moisture and heat transfer. The raw material characterization was performed and afterwards the drying process was conducted at 40 ºC, 50 ºC e 60 ºC, the product temperature was recorded using thermocouples, the air velocity inside the chamber was 4 m·s-1. With the experimental data was possible to validate the diffusion model based on the Fick\'s second law and Fourier. For this purpose, the sorption isotherms were measured and fitted to the GAB model estimating the equilibrium moisture content (Xe), 1.76 [g H2O/100g d.b.] at 60 ºC and 10 % of relative humidity (RH), the thermophysical properties (k, Cp, ?) were also measured to be used in the model. Five cases were contemplated: i) Constant thermophysical properties; ii) Variable properties; iii) Mass (hm), heat transfer (h) coefficient and effective diffusivity (De) estimation 134 W·m-2·K-1, 4.91x10-5 m-2·s-1 and 3.278?10-10 m·s-2 at 60 ºC, respectively; iv) Variable De, it presented a third order polynomial behavior as function of moisture content; v) The shrinkage had an effect on the mathematical model, especially in the 3 first hours of process, the thickness experienced a contraction of about (30.34 ± 1.29) % out of the initial thickness, finding two decreasing drying rate periods (DDR I and DDR II), 3.28x10-10 m·s-2 and 1.77x10-10 m·s-2, respectively. COMSOL Multiphysics simulations were possible to perform through the heat and mass transfer coefficient estimated by the mathematical modeling.

Development of a Mechanism and Process to Continuously Produce Spherical, Torrefied Biomass

Thesis (Master, Mechanical and Materials Engineering) -- Queen's University, 2016-06-17 02:15:25.215

From the initial interest in ‘Why do people often communicate in very "strange" ways on Social Media?’ to a research project on CMC

This presentation is about the inside story of the PhD project El malagueño real, mental y virtual. Configuración de los significados sociales de una variedad urbana in Hispanic Linguistics. That is, the production and perception of the Spanish spoken in the city of Malaga and used on the social network sites Facebook and Tuenti by users from Malaga is analysed. Actually, the southern Spanish variety in question is quite distinct from the national standard in terms of its phonetic features, its prestige, and the attitudes to it. Thus, the project started with the initial interest in «Why do people often communicate in very “strange” ways on social media» which then slightly changed to the final research interest in «What do the different non-standard variants mean in virtual (and real) malagueño?». This long – sometimes hazardous, yet mostly fun – process is exposed in more detail by looking at the research questions, the methods and results. Lastly, the presentation concludes with some lessons learnt and an outlook on possibilities and necessities for further investigation.

Inter-organisational networks, value creation and the process of technology integration in research and development

Traditional methods of R&D management are no longer sufficient for embracing innovations and leveraging complex new technologies to fully integrated positions in established systems. This paper presents the view that the technology integration process is a result of fundamental interactions embedded in inter-organisational activities. Emerging industries, high technology companies and knowledge intensive organisations owe a large part of their viability to complex networks of inter-organisational interactions and relationships. R&D organisations are the gatekeepers in the technology integration process with their initial sanction and motivation to develop technologies providing the first point of entry. Networks rely on the activities of stakeholders to provide the foundations of collaborative R&D activities, business-to-business marketing and strategic alliances. Such complex inter-organisational interactions and relationships influence value creation and organisational goals as stakeholders seek to gain investment opportunities. A theoretical model is developed here that contributes to our understanding of technology integration (adoption) as a dynamic process, which is simultaneously structured and enacted through the activities of stakeholders and organisations in complex inter-organisational networks of sanction and integration.

Accessing chain length dependent termination rate coefficients of methyl methacrylate (MMA) via the reversible addition fragmentation chain transfer (RAFT) process

The RAFT-CLD-T methodology is demonstrated to be not only applicable to 1-substituted monomers such as styrene and acrylates, but also to 1,1-disubstituted monomers such as MMA. The chain length of the terminating macromolecules is controlled by CPDB in MMA bulk free radical polymerization at 80 degrees C. The evolution of the chain length dependent termination rate coefficient, k(t)(i,i), was constructed in a step-wise fashion, since the MMA/CPDB system displays hybrid behavior (between conventional and living free radical polymerization) resulting in initial high molecular weight polymers formed at low RAFT agent concentrations. The obtained CLD of k(t) in MMA polymerizations is compatible with the composite model for chain length dependent termination. For the initial chain-length regime, up to a degree of polymerization of 100, k(t) decreases with alpha (in the expression k(t)(i,i) = k(t)(0) . i(-alpha)) being close to 0.65 at 80 degrees C. At chain lengths exceeding 100, the decrease is less pronounced (affording an alpha of 0.15 at 80 degrees C). However, the data are best represented by a continuously decreasing nonlinear functionality implying a chain length dependent alpha.

Development of a non-intrusive heat transfer coefficient gauge and its application to high pressure die casting Effect of the process parameters

A heat transfer coefficient gauge has been built, obeying particular rules in order to ensure the relevance and accuracy of the collected information. The gauge body is made out of the same materials as the die casting die (H13). It is equipped with six thermocouples located at different depths in the body and with a sapphire light pipe. The light pipe is linked to an optic fibre, which is connected to a monochromatic pyrometer. Thermocouples and pyrometer measurements are recorded with a data logger. A high pressure die casting die was instrumented with one such gauge. A set of 150 castings was done and the data recorded. During the casting, some process parameters have been modified such as piston velocity, intensification pressure, delay before switch to the intensification stage, temperature of the alloy, etc.... The data was treated with an inverse method in order to transform temperature measurements into heat flux density and heat transfer coefficient plots. The piston velocity and the initial temperature of the die seem to be the process parameters that have the greatest influence on the heat transfer. (c) 2005 Elsevier B.V. All rights reserved.

Fast-tracking middle schooling reform: A model for the integrated curriculum

To participate effectively in the post-industrial information societies and knowledge/service economies of the 21st century, individuals must be better-informed, have greater thinking and problem-solving abilities, be self-motivated; have a capacity for cooperative interaction; possess varied and specialised skills; and be more resourceful and adaptable than ever before. This paper reports on one outcome from a national project funded by the Ministerial Council on Education, Employment Training and Youth Affairs, which investigated what practices, processes, strategies and structures best promote lifelong learning and the development of lifelong learners in the middle years of schooling. The investigation linked lifelong learning with middle schooling because there were indications that middle schooling reform practices also lead to the development of lifelong learning attributes, which is regarded as a desirable outcome of schooling in Australia. While this larger project provides depth around these questions, this paper specifically reports on the development of a three-phase model that can guide the sequence in which schools undertaking middle schooling reform attend to particular core component changes. The model is developed from the extensive analysis of 25 innovative schools around the nation, and provides a unique insight into the desirable sequences and time spent achieving reforms, along with typical pitfalls that lead to a regression in the reform process. Importantly, the model confirms that schooling reform takes much more time than planners typically expect or allocate, and there are predictable and identifiable inhibitors to achieving it.

PROFESSORAS BEM-SUCEDIDAS SÃO PROFESSORAS REFLEXIVAS?! A prática da reflexividade nas ações pedagógicas de professoras nos anos iniciais de escolaridade

O presente estudo consiste numa pesquisa processual, de natureza qualitativa, expresso na modalidade narrativa. Tem como pressuposto que o papel do professor implica uma tal responsabilidade que resulta em exigência de aperfeiçoamento constante, para que este profissional possa apresentar-se capaz de uma ação pedagógica bem-sucedida. Um professor, assim caracterizado, corresponde ao profissional efetivamente engajado na prática docente, manifestando atitude de reflexão sobre esta mesma prática, não apenas antes, em sua preparação, mas durante o seu desenrolar e mesmo depois desta, procurando extrair da própria ação elementos que ajudem a constantemente melhorá-la. Sob tais aspectos, destaco a prática reflexiva de Professoras do Ensino Fundamental, nos anos iniciais de escolaridade, especialmente relativa a suas ações pedagógicas bem-sucedidas em aulas, que busco enfocar como objeto de estudo e de investigação nesta dissertação. A coleta de dados da pesquisa deu-se por meio de 1) entrevistas semi-estruturadas, 2) relatos orais, 3) observação de aulas e 4) notas de campo. A análise dos dados, a discussão dos resultados e os encaminhamentos possíveis para a formação de professores foram construídos e expressos levando em conta princípios e critérios da Investigação Narrativa. Das conclusões, tecidas à luz do que resulta desta investigação, destacam-se as que são assim enunciadas: a) as Professoras realizam práticas reflexivas de tipos e níveis diferentes, contudo, tais reflexões ocorrem visivelmente atreladas às suas dificuldades e aos seus conflitos didático-pedagógicos, cada qual em seu contexto específico de ação; b) As Professoras conseguem realizar reflexões na sua ação, bem como reflexões sobre a sua ação com aproximações à literatura pedagógica, ainda que com ausência de explicitação de aspectos sociológicos, filosóficos, políticos, antropológicos, epistemológicos, enfim, dos aspectos que conferem maior criticidade e critério à reflexão, ou seja, atributos de reflexividade. Em função disso, ressalto a importância do progresso da escola em consonância com o progresso e a profissionalização do trabalho docente, através da consideração de cada contexto específico num movimento de busca de sentido para o ensino e para a aprendizagem. Nas considerações finais, propugno para o professor reflexivo compromissos evidentes com o futuro, no presente de suas salas de aula, para que possa ter maior capacidade de resposta pedagógica às necessidades educativas dos seus alunos, que se inserem e vivem na complexa sociedade deste século XXI.