Mandibular growth and dentoalveolar development in the treatment of Class II, division 1, malocclusion using Balters Bionator according to the skeletal maturation

OBJECTIVE: The purpose of the study was to evaluate the influence of the skeletal maturation in the mandibular and dentoalveolar growth and development during the Class II, division 1, malocclusion correction with Balters bionator. METHODS: Three groups of children with Class II, division 1, malocclusion were evaluated. Two of them were treated for one year with the bionator of Balters appliance in different skeletal ages (Group 1: 6 children, 7 to 8 years old and Group 2: 10 children, 9 to 10 years old) and the other one was followed without treatment (Control Group: 7 children, 8 to 9 years old). Lateral 45 degree cephalometric radiographs were used for the evaluation of the mandibular growth and dentoalveolar development. Tantalum metallic implants were used as fixed and stable references for radiograph superimposition and data acquisition. Student's t test was used in the statistical analysis of the displacement of the points in the condyle, ramus, mandibular base and dental points. Analysis of variance one-fixed criteria was used to evaluate group differences (95% of level of significance). RESULTS: The intragroup evaluation showed that all groups present significant skeletal growth for all points analyzed (1.2 to 3.7 mm), but in an intergroup comparison, the increment of the mandibular growth in the condyle, ramus and mandibular base were not statically different. For the dentoalveolar modifications, the less mature children showed greater labial inclination of the lower incisors (1.86 mm) and the most mature children showed greater first permanent molar extrusion (4.8 mm).

Características físicas, reológicas e sensorial de produtos extrusados de misturas de farinha de maracujá e fécula de mandioca

This research had as objective to evaluate the effect of extrusion temperature and screw speed on physical and rheological properties, as well as, the sensory acceptance of cassava and passion fruit snacks produced in single-screw extruder. A central composite design with 11 treatments was used, considering as dependent variables: expansion index (EI), specific volume (SV), water solubility index (WSI), water absorption index (WAI), color (L*, a*, b*) and pasting properties (RVA). The products were flavored and analyzed for global acceptance. The results showed significant effects of temperature and screw speed on the dependent variables. The chocolate flavored snacks obtained good acceptance.

Cassava and turmeric flour blends as new raw materials to extruded snacks

Short cooking time and ability to blend varieties of food ingredients have made extrusion cooking a medium for low-cost and nutritionally improved food products. The effect of moisture, extrusion temperature and amount of turmeric flour mixed with cassava flour on physical characteristic of puffed snacks was evaluated in this work. Extrusion process was carried out using a single-screw extruder in a factorial central composite design with four factors. Results showed effect of extrusion parameters on dependents variables. High expansion, low browning, low water solubility index, intermediate water absorption index and high crispness desirable characteristics to puffed snacks are obtained in conditions of 12% moisture, 5% turmeric flour, 105º C of temperature and 250 rpm of screw speed. These paper point to the potential still unexplored of the use of flours of cassava and turmeric as raw materials in the development of extruded puffed snacks.

Aspectos reprodutivos, morfologia dos gametas e desenvolvimento embrionário de Astyanax altiparanae Garutti & Britski (Teleostei, Characidae)

Pós-graduação em Aquicultura - FCAV

Degradabilidade ruminal da matéria seca de grãos de milho e de sorgo com alto ou baixo conteúdo de tanino processados

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Recuperação de resíduos plásticos provenientes dos processos de injeção

The competitiveness among global markets, the constant need for reducing manufacturing costs and also the growing environmental commitments are fueling the development of techniques for recovery residual parts generated by industrial processes. Among the various areas of a company, we highlight those that involve the processing of raw materials derived from oil, such as polymers (resins), which may take centuries to decompose in the environment and also present as a economic and environmentally strategic point. Thus, this study would examine the recovery of waste polypropylene, from the injection process of a major multinational in the field of home appliances through the recycling by a process comprising the milling, extrusion and chipping of waste material. Easy to deploy, this proposal aims to reduce levels negligible disposal (scrap) of these residues as well as the reintegration of the production process into pieces no visual and no structural importance, aimed at cutting costs and reducing environmental impacts caused. After the survey data in kilograms of waste material generated in a given period of time, and the study of changes in material properties, it would enable the reuse steadily in the injection process

Processo de fabricação de tarugos pelo método HotTop de ligas de alumínio da série 6XXX e as não conformidades desse processamento

The goal of this work is to report some problems that occur in the in the production of aluminum billets (series 6XXX) produced by the hot top process in the Alcoa aluminum Inc. The aluminum fabrication process is described from its first stage, since the mining until the reduction, smelting and treatment of the metal. One of the plant’s final product, are billets for clients that produce profiles by extrusion. The product’s final quality highly depends on the whole production process. Therefore it’s necessary to use good practices in the treatment of the metal, follow up its fabrication and control its thermal treatment, in order to meet the required standards to satisfy the clients. The billet’s production method and its variables will be detailed through temperature and casting speed, cone of water flow, cooling rate, duration of thermal treatment, degassing and metal “in line “filtering, in other words when it’s still found in its liquid state. The non-conformities of the process were studied by metallographic analysis, both macrostutural and microstructural that will be described and discussed in this work

Otimização de custo no processo de fabricação de mangueira hidráulica

A large part of hydraulic hoses is produced on a mandrel. The mandrel has longer length and circular profile being produced by extrusion of polyamide polymer, which in this case is imported, then the process is depending on the import process, which entails high shipping costs and fees. This work studies the production of recycled mandrel, using the mandrel that is out of dimensional to produce hoses. After the production of recycled mandrel mechanical tensile and hardness were performed both in the natural and recycled mandrel to compare them. It was observed that recycled mandrel presents the tensile properties and hardness superior to natural mandrel. Thus, this work will directly impact the company`s business ultimately reducing costs, reducing waste and reducing environmental impacts

Avaliação da integração de implantes de silicone com superfícies lisa, texturizada e de poliuretano em cavidades anoftálmicas evisceradas de coelhos

Pós-graduação em Bases Gerais da Cirurgia - FMB

Estudos de permeação e liberação de peptídeos antimicrobianos estruturalmente derivados da toxina CCDB

O uso de peptídeos sintéticos para o desenvolvimento de novas drogas é uma estratégia promissora no campo da biotecnologia. Peptídeos derivados de toxinas bacterianas intracelulares, produzidas por sistemas de morte pós-segregacional (PKS) tais como CcdB e ParE são exemplos dessa estratégia. Porém, moléculas com estrutura peptídica derivadas de toxinas bacterianas apresentam sérios problemas na aplicação terapêutica por apresentarem baixa solubilidade e difícil permeabilidade em membranas bacterianas. O objetivo desse estudo consistiu no desenvolvimento e aprimoramento de sistemas nanoestruturados (lipossomas) que permita a imobilização de análogos peptídicos da toxina CcdB e sua consequente translocação no citosol bacteriano, permitindo que os mesmos atinjam seus alvos celulares, enzimas DNA girase e Topoisomerase IV. Lipossomas do tipo SUV (small unilamellar vesicles), foram preparados pela técnica de extrusão-evaporação variando-se suas formulações. Desta forma, pretendeu-se avaliar a eficiência de encapsulação dos peptídeos através de técnicas de cromatografia líquida de alta eficiência (CLAE) e espectroscopia de UV-Vis e fluorescência. Após testes de eficiência de encapsulação, os lipossomas contendo os análogos peptídicos encapsulados, foram submetidos a ensaio de inibição de crescimento em meio líquido para duas espécies bacterianas: Staphylococcus aureus e Escherichia coli. Resultados demonstraram que a utilização de sistemas nanoestruturados é de grande importância para viabilizar a aplicação desta classe de biomoléculas em estudos terapêuticos, permitindo assim, que tais peptídeos possam ser utilizados como antibióticos promissores, se associados a sistemas de transporte e liberação controlada de moléculas peptídicas.

Síntese e estudos de sistemas de bioencapsulação associados a peptídeos antimicrobianos miméticos da toxina natural CcdB

Pós-graduação em Biotecnologia - IQ

Avaliação das alterações dentárias e esqueléticas induzidas pelo uso do aparelho de Herbst no tratamento da classe II na dentadura mista: Revisão sistemática

Objective: evaluate the immediate dental and skeletal changes induced by the Herbst appliance on early treatment of Angle´s Class II malocclusion. Material and Method: several electronic databases such as Scopus, Pub Med, Medline, Cochrane Library, Lilacs and Scielo were searched. The abstracts that fullfilled the selection criteria were selected and those that did not provide enough information about these criteria were selected but the final decision of including them or not on the research, was taken after the complete reading of the article. The selection criteria were: clinical studies with Class II individuals, both male and female, with initial age of 7 to 10 years, treated with the Herbst appliance that analysed the dental and/or skeletal changes evaluated on lateral cephalometric radiographs; researches where the treatment performed did not involve extractions or surgical interventions; studies that included patients without syndromes or health concerns and articles published in English or Portuguese. Results and Conclusions: five articles were selected. The articles showed that significant changes happened in the mandibular sagittal lenght, on facial convexity angle, on maxillo-mandibular relationship, on retroclination of the upper incisors and on distal movement of the upper molars, on proclination of the lower incisors and on extrusion of the lower molars. The appliance exerted a limited effect on the anterior relocation of the maxillary complex and on facial heights. However, more studies about the performance of the Herbst appliance on early treatment of Class II are needed.

Mielografia e tomografia computadorizada de afecções compressivas da medula espinhal em cães

Pós-graduação em Cirurgia Veterinária - FCAV

Double-setting alpha-tricalcium phosphate cement provided with interconection channels in rabbits after enucleation: a potential implant for the anophthalmic socket

The purpose of this study was to evaluate the macroscopy and microstructure of a double setting alpha-tricalcium phosphate bone cement sphere provided with interconnection channels (alpha-TCP-i), as well as the integration of the implant with the rabbits' orbital tissue, through macroscopic analysis and histopathology. The external and internal surfaces of the alpha-TCP-i were evaluated macroscopically and by electron microscopy. Twelve New Zealand rabbits received 12mm implants of alpha-TCP-i following enucleation of the left eye. The clinical assessment was undertaken daily during the first 15 days, followed by fortnightly assessment until the end of the study period. For the morphological analysis, exenteration was performed in 3 animals per experimental period (15, 45, 90 and 180 days). The external and internal surfaces of the implant appeared solid, smooth and compact, with six channels which interconnected centrally. The micro-architecture was characterized by the formation of columns of hexagonal crystals. No signs of infection, exposure, dehiscence of sutures or extrusion of the implant were noted in any of the animals during the entire period of the study. The morphological evaluation demonstrated the presence of a thin capsule around the implant, from whence appeared fibro-vascular projections, which penetrated it through the interconnecting channels. In the first days after the insertion of the implant, an intense inflammatory reaction was noted. At 180 days, however, there were no signs of inflammation. The alpha-tricalcium phosphate cement implant was well tolerated in this rabbit model and appeared to be relatively inert with some fibrovascular ingrowth through the large channels.

Site and extent of amino acid digestion in dairy cattle fed with corn and its byproducts

The study was conducted to evaluated the site and extent of dry matter (DM), crude protein (CP), methionine (Met), lysine (Lys), and threonine (Thr) digestion of corn and byproducts obtained from corn germ mixed with different amounts of extruded or non-extruded ether extract (EE) in dairy cattle. Treatments consisted in eight types of feed and two processing in a 4 x 2 factorial design. There were four feeds: corn grain cracked (Corn), corn germ meal with 1% EE (CG1), corn germ meal with 7% EE (CG7), and corn germ meal with 10% EE (CG10). The feeds were processed in one of two ways: extruded (Ex) and not extruded. In situ techniques were used to determine DM, CP, Met, Lys, and Thr partial and total tract digestion. A basic diet was compounded of corn germ meal, soybean meal and coastcross hay in a 70: 30 roughage to concentrate ratio. There was no interaction (P>0.05) between feeds and processing method. Extrusion improved (P<0.05) total tract digestibility of corn DM but not CP. Intestinal digestibility was similar (P>0.05) for corn and corn germ meal mixed with 7 and 10% EE, regardless of EE processing method. The CP total tract digestibility of corn germ meal with 1% non-extruded EE was 16.62% higher (P<0.05) than that of the extruded form. The best total CP digestibility was obtained for corn germ meal with 7% EE, independently of the processing method. The effects of EE processing method on partial and total digestibility differed between amino acid. Corn and corn byproduct extrusion may improve dry matter digestibility, but do not necessarily influence crude protein digestion. Ruminal and intestinal digestibility of Met, Lys, and Thr depends on both feed type and processing method. Therefore, amino acid availability should be considered individually.