Disrupted white matter in language and motor tracts in developmental stuttering

White matter tractsc onnecting areas involved in speech and motor control were examined using diffusion-tensor imagingingin a sample of peoplewhostutter (n=29) who were heterogeneous with respect to age, sex, handedness and stuttering severity. The goals were to replicate previous findings in developmental stuttering and to extend ourknowledge by evaluating the relationship between white matter differences in people who stutter and factors such as age, sex, handedness and stuttering severity. We replicated previous findings that showed reduced integrity in white matter underlying ventral premotorcortex, cerebral peduncles and posteriorcorpus callosum in people who stutter, relative to controls. Tractography analysis additionally revealed significantly reduced white matter integrity in the arcuate fasciculus bilaterally and the left corticospinal tract and significantly reduced connectivity within theleft corticobulbar tract in people who stutter. Region-of-interest analyses revealed reduced white matter integrity in people whostutter in the three pairs ocerebellar peduncles thatcarry the afferent and efferent fibers of the cerebellum. Within thegroup of people who stutter, the higher the stuttering severity index, the lower the white matter integrity in the leftangular gyrus but the greater the white matter connectivity in theleft corticobulbartract. Also,in people who stutter, handedness and age predicted the integrity of the corticospinal tract and peduncles, respectively. Further studies are needed to determine which of these white matter differences relate to the neural basis of stuttering and which reflect experience-dependent plasticity.

Language and thought in bilinguals: the case of grammatical number and nonverbal classification preferences

Recent research shows that speakers of languages with obligatory plural marking (English) preferentially categorize objects based on common shape, whereas speakers of nonplural-marking classifier languages (Yucatec and Japanese) preferentially categorize objects based on common material. The current study extends that investigation to the domain of bilingualism. Japanese and English monolinguals, and Japanese–English bilinguals were asked to match novel objects based on either common shape or color. Results showed that English monolinguals selected shape significantly more than Japanese monolinguals, whereas the bilinguals shifted their cognitive preferences as a function of their second language proficiency. The implications of these findings for conceptual representation and cognitive processing in bilinguals are discussed.

A newly recognized syndrome of marfanoid habitus; Long face; Hypotelorism; Long, thin nose; Long, thin hands and feet; and a specific pattern of language and learning disabilities

Here, we report on a newly recognized syndrome in a Brazilian family with three affected women, who had a Marfanoid habitus; long face; hypotelorism; long, thin nose; long, thin hands and feet; and language and learning disabilities. The disorder is compatible with autosomal dominant inheritance. (C) 2007 Wiley-Liss, Inc.

Linguagem poética e crescimento urbano-industrial / Poetical language and urban-industrial growth

O impacto do crescimento urbano-industrial sobre a lírica moderna é abordado sob o ângulo das dissonâncias ocorridas entre as representações temáticas e os procedimentos expressivos. Assim se confrontam as “respostas” dos poetas europeus à Revolução Industrial e o surgimento das grandes cidades com as dos modernistas brasileiros de 22 face à industrialização de São Paulo. Nestes, ao contrário dos primeiros, os conflitos instauram-se entre a celebração programática da vida moderna e, num primeiro momento, a impossibilidade de adequação de suas formas de expressão ao registro dessa modernidade. Dessa forma se explicam os desequilíbrios temático-expressivos existentes em Paulicéia Desvairada, bem como as adequações conseguidas por obras posteriores. The impact of urban-industrial growth on modern lyrics is approached from the angle of the dissonances which occurred between the thematic representations and the expressive procedures. Thus, the European poets’ responses to the Industrial Revolution and the emergence of the large cities are confronted with those of the 1922 Brazilian Modernists in relation to the industrialization of São Paulo. In the latter, contrary to what happened with ther former ones, the conflicts take place between the programmatic celebration of modern life and, at first, the impossibility of adequating their form of expressions to the record of said modernity. Thus the thematic-expressive disequilibrium in Paulicéia Desvairada, as well as de adequations obtained in later works are explained.