Six Mile Creek Presbyterian Church, Lancaster County, SC Records - Accession 194 - M86 (110)

The Six Mile Presbyterian Church, Lancaster County, SC Records consist of photocopies of a Six Mile Creek Presbyterian Church ledger, containing minutes of church meetings, registers of pastors, elders and deacons, minutes of the church session, registers of communicants, baptisms and deaths. Six Mile Presbyterian Church was started organized sometime around 1804. Included is a note stating the original ledger was rebound in 1971.

Banks Presbyterian Church History - Accession 195 - M87 (111)

The Banks Presbyterian Church History is a history written by Mrs. Lena P. Kell entitled “The Early History of Banks Presbyterian Church” describing the history of the church from 1870s to 1947. The church is located in Waxhaw, North Carolina near Fort Mill. (Photocopies)

Episcopal Church Home For Children Records - Accession 31

The Episcopal Church Home For Children Records are a valuable source on the Church’s historical effort to extend its services for the social improvement of South Carolina (in this case the Episcopal Diocese’s program for destitute children.) The Episcopal Church Home was established in 1850 in Charleston, S.C. for orphan girls and was chartered by the S.C. General Assembly in 1852. The collection consists of a history, minutes, reports of the annual meetings, general correspondence, superintendent’s records, health records, attendance registers, financial records, newsletters (both bound and unbound), and photographs.

Bethel Baptist Church of Sumter, SC, History - Accession 209 - M93 (119)

The Bethel Baptist Church of Sumter, SC History consists of a short history of Bethel Baptist Church in Sumter, SC from its beginning in 1780 to 1974.

Family and Church Records - Accession 49 - M22 (32-33)

The Family and Church Records consist of photocopies of records compiled by Mrs. W.H. Hamilton, Mrs. Fred C. Laurence and Mrs. L.F. Abernethy for the Catawba Chapter of the Daughters of the American Revolution. The collection includes mostly genealogical information including a history of the Crawford family, Reid family bible records, Roach family bible records, Joseph Palmer Moore obituary, Moore family chart, Andrew Jackson, Sr. and Elizabeth Jackson monument, Commission from Gen. Francis Marion to Captain James Witherspoon, Witherspoon family records, Alexander Love biographical information, and a cemetery list of Bethel Presbyterian Church.

Fishing Creek Presbyterian Church of Chester County Records

The Fishing Creek Presbyterian Church of Chester County Records include an historical statement (1839) on its origin and development by one of its pastors Rev. John B. Davies, and copies of entries for various sessions containing information on how the church handled misconduct of its members.

Second Baptist Church, Kershaw, S.C. Records - Accession 51

The Second Baptist Church, Kershaw, SC Records consist of photocopies of the church’s records including minutes, membership lists, and financial records relating to the day-to-day operation and business of the church.

Church Women United in Columbia Records - Accession 191

The Church Women United In Columbia was founded in 1915 as the Women’s Interdenominational Missionary Union whose purpose was to work for the betterment of social and economic conditions in the city of Columbia, South Carolina. The collection consists of constitutions, bylaws, minutes, correspondence, reports, financial records, newsletters, newspaper clippings, lists, and other records relating to the history and civic activities of the organization.

Celestial Church of Christ in Italia. Percorsi, Spazi e Pratiche Rituali

Il lavoro che presento propone un’analisi di una chiesa africana indipendente in Italia, la Celestial Church Of Christ Worldwide (CCCW), cercando di mettere in luce il nesso tra religione, migrazione e il processo di ‘plunting churches’ (Kooning 2009) nel contesto italiano. Attraverso una ricerca sul campo, sono stati indagati i percorsi personali, familiari e comunitari dei membri di una ‘Celestial Parish’ presente nel comune di Brescia, ‘Ileri Oluwa Parish’, al fine di comprendere la natura dei processi identitari coinvolti nell’organizzazione della CCC in Italia. ‘Ileri Oluwa Parish’, in quanto luogo che denota una ‘chiesa individuale collegata ad una Diocesi’ (CCC Constitution (CCC Constitution, 107 (d) si rivela, nella materialità delle sue forme e dei ‘Devotional Services’ che in essa si svolgono, a ‘field of action’ (Lefebvre, 1991). La storia della chiesa, i fondamenti della sua dottrina e i significati comunicati attraverso le forme rituali e religiose che la stessa promuove, sono stati contestualizzati alla luce delle tensioni e delle strategie di potere che strutturano il campo. Le storie dei membri della parrocchia, percorsi di migrazione e mobilità in itinere, rappresentano la lente attraverso cui si è guardato alle relazioni vissute nel nome dello ‘Spirito’, e alla percezione stessa di ciò che gli stessi Celestians definiscono sacro, santo, puro e impuro. Lo sguardo fisso alla vita ordinaria di una Celestial parish in Italia, esteso nell’ultima parte dell’elaborato alla Celestial parish londinese, è stato fondamentale per capire l’intreccio di relazioni spirituali, reti familiari e mobilità degli individui sul territorio italiano ed europeo, processo che ribalta la condizione diasporica della CCC, trasformando una condizione di dispersione in un valore aggiunto, nella possibilità di nuove traiettorie territoriali e spazi di presenza religiosa e socioeconomica.

The search for Multiple Myeloma Stem cells: molecular characterization and self-renewal mechanisms involved in the disease persistence

The existence of Multiple Myeloma Stem cells (MMSCs)is supposed to be one of the major causes of MM drug-resistance. However, very little is known about the molecular characteristics of MMSCs, even if some studies suggested that these cells resembles the memory B cells. In order to molecularly characterize MMSCs, we isolated the 138+138- population. For each cell fraction we performed a VDJ rearrangement analysis. The complete set of aberrations were performed by SNP Array 6.0 and HG-U133 Plus 2.0 microarray analyses (Affymetrix). The VDJ rearrangement analyses confirmed the clonal relationship between the 138+ clone and the immature clone. Both BM and PBL 138+ clones showed exactly the same genomic macroalterations. In the BM and PBL 138-19+27+ cell fractions several micro-alterations (range: 1-350 Kb) unique of the memory B cells clone were highlighted. Any micro-alterations detected were located out of any genomic variants region and are presumably associated to the MM pathogenesis, as confirmed by the presence of KRAS, WWOX and XIAP genes among the amplified regions. To get insight into the biology of the clonotypic B cell population, we compared the gene expression profile of 8 MM B cells samples 5 donor B cells vs, thus showing a differential expression of 11480 probes (p-value: <0,05). Among the self-renewal mechanisms, we observed the down-regulation of Hedgehog pathway and the iperactivation of Notch and Wnt signaling. Moreover, these immature cells showed a particular phenotype correlated to resistance to proteasome inhibitors (IRE1α-XBP1: -18.0; -19.96. P<0,05). Data suggested that the MM 138+ clone might resume the end of the complex process of myelomagenesis, whereas the memory B cells have some intriguing micro-alterations and a specific transcriptional program, supporting the idea that these post germinal center cells might be involved in the transforming event that originate and sustain the neoplastic clone.

Città e architettura a Faenza nel Rinascimento. Progetti e strategie di rinnovamento urbano nell'età di Carlo II Manfredi (1468-77)

La tesi ha come oggetto il rinnovamento urbano che fu realizzato a Faenza per opera del suo signore Carlo II Manfredi tra il 1468 e il 1477, d’accordo con il fratello, il vescovo Federico. La prima opera realizzata da Carlo fu il portico a due livelli che dotò di una nuova facciata il suo palazzo di residenza, di origini medievali. Questa architettura sarebbe stata il preludio di un riordino generale della piazza principale della città, probabilmente allo scopo di ricreare un foro all’antica, come prescritto dai trattati di Vitruvio e di Alberti. L’aspetto originale del loggiato rinascimentale, desumibile da documentazione archivistica e iconografica, permette di attribuirlo con una certa probabilità a Giuliano da Maiano. Oltre alla piazza, Carlo riformò profondamente il tessuto urbano, demolendo molti portici lignei di origine medievale, rettificando le principali strade, completando la cerchia muraria. Federico Manfredi nel 1474 diede inizio alla fabbrica della Cattedrale, ricostruita dalle fondamenta su progetto dello stesso Giuliano da Maiano. L’architettura della chiesa ha uno stile largamente debitore all’architettura sacra di Brunelleschi, ma con significative differenze (come la navata definita da un’alternanza tra pilastri e colonne, o la copertura composta da volte a vela). L’abside della cattedrale, estranea al progetto maianesco, fu realizzata nel 1491-92 e mostra alcuni dettagli riconducibili alla coeva architettura di Bramante. A Faenza si realizza in un periodo di tempo brevissimo una profonda trasformazione del volto della città: loggiato, riforma della piazza, riordino delle strade, una nuova cattedrale, tutto contribuisce a dare lustro ai Manfredi e a fare di Faenza una città moderna e in cui si mettono in pratica, forse per la prima volta nell’Italia settentrionale, i dettami di Vitruvio e di Alberti.