A lei aplicável à sociedade anónima europeia (societas europaea)

The possibility of creating a European Company is a reality about ten years. However, there are issues related to the determination of the law applicable to companies of national law with several years of discussion. It is this link between companies under national law of many Member States of the European Union and the possibility of creating a European company which denotes the importance of determining the seat of commercial companies in defining the law applicable to societas europaea; Are we facing an endless web of corporate seats.

The long-term effect of active immunization against inhibin in goats

This experiment addresses the long-term effect of active immunization of goats against a recombinant ovine inhibin alpha subunit (roIHN-alpha). In late anestrus 100 mu g of roINH-alpha was administered to 40 pluriparous Boer goat does, followed, 4 weeks later, by a booster injection. Weekly blood samples were drawn to monitor the inhibin binding capacity with the aid of a radio-tracer binding assay. From the onset until 48 h after the end of each estrus, follicular development and ovulation rate were monitored at 24 h intervals by transrectal ultrasonography. Beginning in August and continuing into January, does were mated at every other estrus, and submitted to transcervical embryo collection. Seven months after the first immunization, the does were mated again and permitted to carry to term. All immunized does produced inhibin antibodies, an elevated titre being first detected 2 weeks after primary immunization. Maximum titres were reached after 6 weeks, i.e. 2 weeks after the booster injection. Thereafter, in the course of the following 32 weeks, the titre subsided gradually. The does started cycling by mid-August. At that stage the average number of follicles more than 4 mm in diameter, ovulations and total embryos and ova recovered were 14.7 (+/- 2.3), 5.3 (+/- 0.7) and 4.4 (+/- 1.0), respectively. A steady decline followed and in January the corresponding means were: 5.2 (+/- 0.6) follicles, 3.1 (+/- 0.6) ovulations and 1.2 (+/- 0.4) embryos and ova recovered. When mated toward the end of the breeding season, 85% of the does became pregnant to the first mating and 73% went to term. Healthy kids were born, the average litter size being 2.2 (+/- 0.1). In conclusion, immunization of goats against a recombinant inhibin alpha-subunit proved to be a practicable means of producing embryos for transfer purposes. After about half a year, when the inhibin antibody titre has subsided, it is possible to return the does to the breeding flock without risking complications with normal breeding activity. (c) 2009 Elsevier Inc. All rights reserved.

Superovulation and embryo collection in nulliparous Boer goat does immunized against a recombinant ovine alpha-subunit inhibin

With the purpose of eliciting a superovulatory response, 12 adult nulliparous Boer goat does were actively immunized against a recombinant a-subunit of ovine inhibin (roIHN-alpha; two injections of 100 mg 4 weeks apart). Another 12 control Boer goat does were treated with physiological saline and acted as controls. One year later the immunized animals were boostered by the administration of another dose (100 mg) of the immunogen. Following treatment, blood samples were collected twice weekly for the periods of 16 and 12 weeks, respectively, to monitor the inhibin binding ability with the aid of a radio-tracer binding assay. Throughout the experiment, estrus detection was conducted twice daily with the aid of an aproned intact buck. From the first day after treatment to 48 h after standing estrus, ovarian activity was monitored daily by transrectal ultrasonography. On alternate estrous cycles, does were mated and 6 days later flushed transcervically to recover embryos. All goats treated with the roIHN-alpha produced antibodies reactive to the native bovine inhibin tracer-the titre increasing from 2.9 +/- 0.4 to a maximum of 21.9 +/- 2.9% binding after the second injection. The antibody titre gradually subsided over the next 16 weeks. The booster injection restored an elevated antibody titre (11.7 +/- 0.4%), which was maintained until the end of the sampling period 12 weeks later. In the control goats only trace amounts of antibody were recorded throughout the trial. In the roIHN-alpha-immunized goats the number of follicles reaching a diameter of > 4 mm was 14.6 +/- 1.2 per doe. A positive correlation was recorded between the follicle number and antibody titre (r=0.61; P < 0.01). The number of follicles ovulating per doe (6.9 +/- 0.7) followed the same tendency-however, the proportion decreased with increasing follicle numbers. A relatively weak correlation was recorded between the inhibin binding ability and number of ovulations (r=0.27; P < 0.05). In the control goats the majority (92%) of follicles exceeding 4 mm in diameter ovulated (2.5 +/- 0.1 follicles/doe). Embryo collection proved unsatisfactory (42% versus 39% recovery for immunized and control animals, respectively)-presumably because the uterine lumen of the nulliparous does was too narrow to permit effective flushing. In the group of immunized goats the occurrence of short estrous cycles (< 15 days) recorded was 34% versus only 6% in the controls. Overall, immunization of goats against roIHN-alpha led to an almost six-fold increase in number of ovarian follicles, a three-fold increase in ovulations and, despite the low recovery rate, a more than three-fold increase in ova or embryos recovered. It may be concluded that treatment of female goats with roIHN-alpha leads to an inhibin antibody response, accompanied by enhanced ovarian activity. The response was, however, accompanied by a large proportion of retained follicles and a high incidence of short estrous cycles. These problems need to be further investigated before rendering the method fit for application in embryo transfer programs in goats. (C) 2007 Elsevier B.V. All rights reserved.

Study on indoor thermal environment and air quality of office rooms controlled by personal displacement ventilation using CFD

Three-dimensional computational simulations are performed to examine indoor environment and micro-environment around human bodies in an office in terms of thermal environment and air quality. In this study, personal displacement ventilation (PDV), including two cases with all seats taken and two middle seats taken, is compared with overall displacement ventilation (ODV) of all seats taken under the condition that supply temperature is 24℃ and air change rate is 60 l/s per workstation. When using PDV, temperature stratification, the characteristic of displacement ventilation, is obviously observed at the position of occupant’s head and clearer in the case with all seats taken. Verticalertical ertical temperature temperature temperature temperature temperature differences below height of the head areare under under under 2℃ in two cases in two cases in two cases in two cases in two cases in two cases in two cases in two cases with all seats taken，and the temperature with PDV is higher than that with ODV. Verticalertical ertical temperature temperature temperature temperature temperature temperature difference is under 3 under 3under 3 under 3℃ in the case in the case in the case in the case in the case in the case in the case with two middle seats taken. CO2 concentration is lower th is lower th is lower this lower this lower than 2 g/man 2 g/m an 2 g/man 2 g/man 2 g/man 2 g/m 3 in the breath zone. in the breath zone. in the breath zone. in the breath zone. in the breath zone. in the breath zone. in the breath zone. in the breath zone. in the breath zone. The results indicate that PDV can be used in the room with big change of occupants’ number to satisfy the need of thermal comfort and air quality. When not all seats are taken, designers should increase supply air requirement or reduce its temperature for thermal comfort. INDEX TERMS

Gender diversity and board performance: women's experiences and perspectives

Despite considerable progress that organizations have made during the past 20 years to increase the representation of women at board level, they still hold few board seats. Drawing on a qualitative study involving 30 companies with women directors in the United Kingdom, the United States, and Ghana, we investigate how the relationship between gender in the boardroom and corporate governance operates. The fi ndings indicate that the presence of a minority of women on the board has an insignifi cant effect on board performance. Yet the chairperson’s role is vital in leading the change for recruiting and evaluating candidates and their commitment to the board with diversity and governance in mind. Our study also sheds light on the multifaceted reasons why women directors appear to be resisting the discourse of gender quotas.

Differential effects of formaldehyde exposure on the cell influx and vascular permeability in a rat model of allergic lung inflammation

Exposure to air pollutants such as formaldehyde (FA) leads to inflammation, oxidative stress and immune-modulation in the airways and is associated with airway inflammatory disorders such as asthma. The purpose of our study was to investigate the effects of exposure to FA on the allergic lung inflammation. The hypothesized link between reactive oxygen species and the effects of FA was also studied. To do so, male Wistar rats were exposed to FA inhalation (1%, 90 min daily) for 3 days. and subsequently sensitized with ovalbumin (OVA)-alum by subcutaneous route One week later the rats received another OVA-alum injection by the same route (booster). Two weeks later the rats were challenged with aerosolized OVA. The OVA challenge of rats upon FA exposure induced an elevated release of LTB(4). TXB(2), IL-1 beta, IL-6 and VEGF in lung cells, increased phagocytosis and lung vascular permeability, whereas the cell recruitment into lung was reduced. FA inhalation induced the oxidative burst and the nitration of proteins in the lung Vitamins C, E and apocynin reduced the levels of LTB(4) in BAL-cultured cells of the FA and FA/OVA groups, but Increased the cell influx into the lung of the FA/OVA rats. In OVA-challenged rats, the exposure to FA was associated to a reduced lung endothelial cells expression of intercellular cell adhesion molecule 1 (ICAM-1) In conclusion, our findings suggest that FA down regulate the cellular migration into the lungs after an allergic challenge and increase the ability of resident lung cells likely macrophages to generate inflammatory mediators, explaining the increased lung vascular permeability Our data are indicative that the actions of FA involve mechanisms related to endothelium-leukocyte interactions and oxidative stress, as far as the deleterious effects of this air pollutant on airways are concerned. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

CD8(+) T cell adjuvant effects of Salmonella FliCd flagellin in live vaccine vectors or as purified protein

Salmonella flagellin, the flagellum structural subunit, has received particular interest as a vaccine adjuvant conferring enhanced immunogenity to soluble proteins or peptides, both for activation of antibody and cellular immune responses. In the present study, we evaluated the Salmonella enterica FliCd flagellin as a T cell vaccine adjuvant using as model the 9-mer (SYVPSAEQI) synthetic H2(d)-restricted CD8(+) T cell-specific epitope (CS(280-288)) derived from the Plasmodium yoelii circumsporozoite (G) protein. The FliCd adjuvant effects were determined under two different conditions: (i) as recombinant flagella, expressed by orally delivered live S. Dublin vaccine strains expressing the target CS(280-288) peptide fused at the central hypervariable domain, and (ii) as purified protein in acellular vaccines in which flagellin was administered to mice either as a recombinant protein fused or admixed with the target CS(280-288) peptide. The results showed that CS(280-288)-specific cytotoxic CD8(+) T cells were primed when BALB/c mice were orally inoculated with the expressing the CS280-288 epitope S. Dublin vaccine strain. In contrast, mice immunized with purified FliCd admixed with the CS280-288 peptide and, to a lesser extent, fused with the target peptide developed specific cytotoxic CD8(+) T cell responses without the need of a heterologous booster immunization. The CD8(+) T cell adjuvant effects of flagellin, either fused or not with the target peptide, correlated with the in vivo activation of CD11c(+) dendritic cells. Taken together, the present results demonstrate that Salmonella flagellins are flexible adjuvant and induce adaptative immune responses when administered by different routes or vaccine formulations. (C) 2009 Elsevier Ltd. All rights reserved.

Classroom of students watching demonstration of closed-circuit TV

Students watch monitors that show a voltage meter being filmed in the Automotive Dept by department head William C. H. Meyer as part of a demonstration of a new technique in closed-circuit television. This is one of a series of photographs accompanying a press release about the development and demonstration of the new technique at the New York Trade School. Original caption reads, "In a classroom on another floor, students all have "front row" seats for the demonstration. Camera concentrates on close-up of a meter, where readings show the result of the voltage-regulator check. Instructor (standing at microphone) is Arthur Richards." Black and white photograph with accompanying caption.

As atividades culturais no eixo da Avenida Paulista

A Avenida Paulista ocupa uma importância central na cidade de São Paulo sob muitos pontos de vista: pela concentração das sedes do poder econômico - particularmente do capital financeiro -, manifestações políticas, comemorações, etc. Além dessas dimensões, a avenida também figura na condição de importante pólo cultural, representado pelo MASP, bem como por uma série de atividades promovidas por federações, instituições bancárias ou novas galerias, a maioria envolvidas com o marketing cultural. A organização interna dessas instituições e a composição do público freqüentador são aqui analisados numa perspectiva sociológica.

Governança corporativa: a formação de mecanismos por investidores institucionais, o caso PREVI

O objetivo geral deste trabalho de dissertação de mestrado é identificar e analisar os principais fatores históricos e institucionais que contribuíram para a formação dos atuais mecanismos de govemança corporativa adotados pela Caixa de Previdência dos Funcionários do Banco do Brasil (PREVI) em relação às empresas em que detém participação acionária relevante. Tendo como foco da investigação o centenário e maior fundo de pensão da América Latina, com investimentos totais da ordem de US$ 20 bilhões, o estudo visa a resgatar e registrar a evolução de processo extremamente importante no campo da govemança corporativa no Brasil e no próprio desenvolvimento do mercado de capitais no País. A identificação dos primeiros elementos característicos de atuação da Entidade, ou de sua manifesta influência no estabelecimento de políticas e estratégias de companhias em que participa, marca o começo da investigação, no início da década de 90 do século passado. Adotou-se como limite temporal do estudo o ano de 2003, na medida em que ali ocorre a efetiva implantação do Modelo Previ de Govemança Corporativa, concebido e desenvolvido ao longo dos três anos anteriores. A formação de mecanismos de govemança corporativa pela PREVI deu-se de maneira gradual, estimulada pelo aumento do volume de participações e pelo crescimento do número de assentos em conselhos de administração e fiscal que atingiria 367, entre titulares e suplentes, distribuídos em 95 empresas, em fins de 2003. o trabalho, enquadrado com base na taxonomia de Yin (2002) como um Estudo de Caso Único, adotou, como fonte de evidências, documentos, registros em arquivos e entrevistas, buscando conduzir pesquisa longitudinal com cortes transversais, captando a evolução do assunto ao longo do tempo por meio de recuperação de dados em momentos de significância destacada. O trabalho procura ainda alcançar aspectos motivacionais para a atuação da Instituição, buscando referência em estudos já desenvolvidos sobre o tema.

História, memória e patrimônio da Escola Militar do Realengo

Esta dissertação analisa a influência das instituições militares, particularmente a Escola Militar, no período de 1912 a 1944, na configuração urbana de Realengo, bairro localizado no subúrbio do município do Rio de Janeiro. Tendo como principal corpus documental os relatórios do Ministério da Guerra e a legislação pertinente, são estabelecidos marcos históricos para análise do processo de transformação da antiga zona rural do município em uma área militar, enfatizando os impactos que incidiram sobre a região em decorrência da transferência da sede da Escola Militar do Brazil, da Praia Vermelha para o Realengo. Preliminarmente, são identificadas as primeiras unidades militares que ocuparam a região, estabelecendo conexões entre o funcionamento dessas organizações, a constituição do seu patrimônio e o desenvolvimento urbano de Realengo. Para contextualização, também são apresentadas as sedes ocupadas pela Escola Militar ao longo do século XIX e as circunstâncias que motivaram sua saída da Praia Vermelha no início do século XX. O recorte temporal se inicia no período compreendido entre o início do século XIX, quando as chamadas terras realengas foram doadas à Câmara da cidade do Rio de Janeiro por D. João VI; atravessa o século XX, quando se consolidaram o patrimônio da Escola Militar em Realengo e a urbanização do bairro; e chega aos dias atuais, quando, após a extinção da escola, a decadência e o abandono são as marcas das antigas edificações militares do bairro. Também são assinalados o funcionamento da Fábrica de Cartuchos e a criação de duas grandes áreas militares, a Vila Militar de Deodoro e o Campo dos Afonsos. Por fim, são levantadas as perspectivas e ações do Exército Brasileiro e de outros órgãos da sociedade na preservação do patrimônio e da memória da antiga escola.

The executive toolbox: building legislative support in a multiparty presidential regime

How do presidents win legislative support under conditions of extreme multipartism? Comparative presidential research has offered two parallel answers, one relying on distributive politics and the other claiming that legislative success is a function of coalition formation. We merge these insights in an integrated approach to executive-legislative relations, also adding contextual factors related to dynamism and bargaining conditions. We find that the two presidential “tools” – pork and coalition goods – are substitutable resources, with pork functioning as a fine-tuning instrument that interacts reciprocally with legislative support. Pork expenditures also depend upon a president’s bargaining leverage and the distribution of legislative seats.

Educação para a igualdade na perspectiva de gênero

Este trabalho tem como principal objetivo refletir sobre as questões de gênero e diversidade nas políticas públicas de educação no Brasil. O propósito foi analisar o esforço investido em mudanças no processo de formação básica, que buscam tornar a escola um lugar mais igualitário, preparado para cumprir seu papel na formação de sujeitos para o exercício da cidadania. Também foi finalidade da pesquisa captar a percepção dos educadores em face desse esforço. Como estudo de caso, foi tomado o curso piloto do projeto Gênero e Diversidade na Escola (GDE), que propõe, através de formação complementar, uma discussão com educadores sobre assuntos da diversidade, gênero, sexualidade e relações étnico-raciais. O curso GDE, realizado no ano de 2006, ofertou 1200 vagas para professores do ensino fundamental de seis municípios das cinco regiões brasileiras: Dourados/MS, Niterói e Nova Iguaçu/RJ, Maringá/PR, Porto Velho/RO e Salvador/BA. Para viabilizar a pesquisa foram analisados 60 memoriais, desenvolvidos como parte da avaliação final dos professores que participaram do projeto.

Conselheiros municipais e vereadores : luta por reconhecimento na esfera pública

O objetivo desta pesquisa foi analisar como conselheiros municipais e vereadores do Recife reconhecem o direito à participação na gestão pública e o direito à representação eleitoral e às funções daí decorrentes. Deste modo, podem-se observar os impactos ocasionados pela instância de participação em uma instituição tradicional de representação política, de modo a aperfeiçoar o modelo de Gestão Social. A análise foi realizada à luz da teoria do reconhecimento, especificamente as ideias de Axel Honneth. Para tanto, foram aplicados questionários e realizadas entrevistas com conselheiros e vereadores do Município, assim como foram analisados documentos da Câmara. Observou-se que ambos os grupos mostram-se favoráveis ao diálogo entre as instâncias, apesar dos conflitos que ainda precisam ser vencidos. Vereadores têm assento nos conselhos, apesar de que a participação não acontece na prática. Concluiu-se que o reconhecimento não ocorre em sua integralidade, sendo uma luta em construção.

Executivo e legislativo no âmbito municipal: a formação de gabinetes no município de São Paulo (1989-2012)

O desenho político-institucional dos municípios brasileiros segue a lógica da esfera federal. Tal sistema tem por características gerais o termo de duração fixa e próprio, tanto para o Executivo quanto para o Legislativo, ou seja, ambos são eleitos diretamente – eleições majoritárias e proporcionais, respectivamente – sem estarem sujeitos à confiança mútua como no sistema parlamentarista. Dada a separação de poderes e o conflito que a literatura ressalta no âmbito federal entre Legislativo e Executivo, o estudo examina a estrutura da dinâmica dessa relação no âmbito municipal. Nesse sentido, o escopo tange as estratégias adotadas na formação dos gabinetes no município de São Paulo de 1989 a 2012, ou seja, contempla 6 (seis) diferentes gestões paulistanas. Para isso foi investigado o perfil político-partidário do secretariado e a correspondência em termos de cadeiras no Legislativo paulistano, bem como os resultados acerca da aprovação de proposituras de iniciativa do Executivo. Os resultados encontrados destacam que a distribuição de pastas não acarreta em um suporte da maioria do parlamento, como no caso federal. Entretanto, apesar da ausência desse apoio, praticamente todos os projetos do Executivo que chegaram ao Plenário foram aprovados. Assim, o estudo aponta que o compartilhamento de poder através da nomeação de secretários partidários é uma ferramenta importante do Executivo, porém pode não ser a única garantidora de uma coalizão majoritária que explique o sucesso legislativo do prefeito.