Concerto no. 3 in G major, Köchel no. 216 for violin & pianoforte. [music] /

Acc. originally for orchestra.

Traité pratique de l'art des accouchemens : accompagné de 216 figures gravées sur bois intercalées dans le texte /

Mode of access: Internet.

Boy's fun book of things to make and do; 216 ways to have fun, 470 how-to-do-it illustrations.

Mode of access: Internet.

Tower AB-216/U, tower section set AB-298/U, guy kit MK-99/U, accessory kit MK-100/U, guy kit MK-101/U.

"June 1956."

Field and depot maintenance manual : propelling unit, marine outboard, diesel driven, 165 hp, design 9002 (Murray & Tregurtha Harbormaster model OA6(TC)) serial numbers 216 thru 305, FSN 2010-278-0793.

"February 1962."

Operators, unit, intermediate (DS) and intermediate (GS) maintenance manual for engine, diesel, Caterpillar, model 3508, NSN 2815-01-216-0938.

"25 July 1986."

Operator's, unit, intermediate (DS), and intermediate (GS) maintenance manual for engine, diesel, Cummins model NTA-855-L4, NSN 2815-01-216-0939.

"25 July 1986."

Direct support and general support maintenance repair parts and special tools lists : crane, truck, warehouse, 10,000 lb. capacity, GED, pneumatic tires Army model MHE 216, NSN 3950-00-197-4935, Pettibone model 10FM.

Includes indexes.

Organizational maintenance repair parts and special tools lists : crane, truck, warehouse, 10,000 lb. capacity, GED, pneumatic tires, Army model MHE 216, NSN 3950-00-197-4935, Pettibone model 10FM.

Includes index.

Operator and organizational maintenance manual : crane, truck, warehouse, 10,000 lb. capacity, GED, PT Pettibone model 10FM, Army model MHE 216, FSN 3950-197-4935.

"July 1971."

Yunnan tong zhi gao : 216 juan, juan shou 3 juan /

Mu ke ben. Kuang : 21.8 cm x 16 cm.

Role of glutamic acid 216 in cytochrome P450 2D6 substrate binding and catalysis

Human cytochrome P450 (P450) 2D6 is an important enzyme involved in the metabolism of drugs, many of which are amines or contain other basic nitrogen atoms. Asp301 has generally been considered to be involved in electrostatic docking with the basic substrates, on the basis of previous modeling studies and site-directed mutagenesis. Substitution of Glu216 with a residue other than Asp strongly attenuated the binding of quinidine, bufuralol, and several other P450 2D6 ligands. Catalytic activity with the substrates bufuralol and 4-methoxyphenethylamine was strongly inhibited by neutral or basic mutations at Glu216 (>95%), to the same extent as the substitution of Asn at Asp301. Unlike the Asp301 mutants, the Gln216 mutant (E216Q) retained 40% enzyme efficiency with the substrate spirosulfonamide, devoid of basic nitrogen, suggesting that the substitutions at Glu216 affect binding of amine substrates more than other catalytic steps. Attempts to induce catalytic specificity toward new substrates by substitutions at Asp301 and Glu216 were unsuccessful. Collectively, the results provide evidence for electrostatic interaction of amine substrates with Glu216, and we propose that both of these acidic residues plus at least another residue(s) is (are) involved in binding the repertoire of P450 2D6 ligands.

Lei 10.216

O objetivo deste recurso é apresentar, construir um novo estatuto social para o doente mental, que lhe garanta cidadania.

Sistema limpo em linha para extração em fase sólida de contaminantes emergentes em águas naturais

A solid-phase in-line extraction system for water samples containing low levels of emerging contaminants is described. The system was specially developed for large volume samples (up to 4 L) using commercial solid-phase extraction (SPE) cartridges. Four sets containing PTFE-made connectors, brass adapters and ball valves were used to fit SPE cartridges and sample bottles to a 4-port manifold attached to a 20 L carboy. A lab-made vacuum device was connected to the manifold cap. The apparatus is robust and less expensive than the typical available system. Its also provides less experimental handling, avoiding cross contamination and sample losses.

Uso de redes neurais artificiais na identificação de vocalização de suínos

Animal welfare has been an important research topic in animal production mainly in its ways of assessment. Vocalization is found to be an interesting tool for evaluating welfare as it provides data in a non-invasive way as well as it allows easy automation of process. The present research had as objective the implementation of an algorithm based on artificial neural network that had the potential of identifying vocalization related to welfare pattern indicatives. The research was done in two parts, the first was the development of the algorithm, and the second its validation with data from the field. Previous records allowed the development of the algorithm from behaviors observed in sows housed in farrowing cages. Matlab® software was used for implementing the network. It was selected a retropropagation gradient algorithm for training the network with the following stop criteria: maximum of 5,000 interactions or error quadratic addition smaller than 0.1. Validation was done with sows and piglets housed in commercial farm. Among the usual behaviors the ones that deserved enhancement were: the feed dispute at farrowing and the eventual risk of involuntary aggression between the piglets or between those and the sow. The algorithm was able to identify through the noise intensity the inherent risk situation of piglets welfare reduction.