Stellenwert der prä- und intraoperativen Diagnostik bei malignen Tumoren der Schilddrüse

Magdeburg, Univ., Medizin. Fak., Diss., 2004

Technologien im Produktentwicklungsprozess : mit Fokus auf Produkte der biomedizinischen Technik

Biomedical Technology, Product Development, Rapid Prototyping, Master in Mechanical Engineering, Tertiary Education

Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort

Background: The maternal cardiovascular system undergoes progressive adaptations throughout pregnancy, causing blood pressure fluctuations. However, no consensus has been established on its normal variation in uncomplicated pregnancies. Objective: To describe the variation in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels during pregnancy according to early pregnancy body mass index (BMI). Methods: SBP and DBP were measured during the first, second and third trimesters and at 30-45 days postpartum in a prospective cohort of 189 women aged 20-40 years. BMI (kg/m2) was measured up to the 13th gestational week and classified as normal-weight (<25.0) or excessive weight (≥25.0). Longitudinal linear mixed-effects models were used for statistical analysis. Results: A decrease in SBP and DBP was observed from the first to the second trimester (βSBP=-0.394; 95%CI: -0.600- -0.188 and βDBP=-0.617; 95%CI: -0.780- -0.454), as was an increase in SBP and DBP up to 30-45 postpartum days (βSBP=0.010; 95%CI: 0.006-0.014 and βDBP=0.015; 95%CI: 0.012-0.018). Women with excessive weight at early pregnancy showed higher mean SBP in all gestational trimesters, and higher mean DBP in the first and third trimesters. Excessive early pregnancy BMI was positively associated with prospective changes in SBP (βSBP=7.055; 95%CI: 4.499-9.610) and in DBP (βDBP=3.201; 95%CI: 1.136-5.266). Conclusion: SBP and DBP decreased from the first to the second trimester and then increased up to the postpartum period. Women with excessive early pregnancy BMI had higher SBP and DBP than their normal-weight counterparts throughout pregnancy, but not in the postpartum period.

Speed in early visual processing

Vision, Speed, Electroencephalogram, Gamma Band Activity

Funktionelle und morphologische Analyse der Läsionsplastizität nach transienter zerebraler Ischämie

Thallium-autometallographie, electrophysiology in vivo,ischemia, neurogenesis, microglia

Incidence and Predictors of Cardiovascular Complications and Death after Vascular Surgery

AbstractBackground:Patients undergoing arterial vascular surgery are considered at increased risk for post-operative complications.Objective:To assess the incidence and predictors of complications and death, as well as the performance of two models of risk stratification, in vascular surgery.Methods:This study determined the incidence of cardiovascular complications and deaths within 30 days from surgery in adults. Univariate comparison and logistic regression assessed the risk factors associated with the outcomes, and the receiver operating characteristic (ROC) curve assessed the discriminatory capacity of the revised cardiac risk index (RCRI) and vascular study group of New England cardiac risk index (VSG-CRI).Results:141 patients (mean age, 66 years; 65% men) underwent the following surgeries: carotid (15); lower limbs (65); abdominal aorta (56); and others (5). Cardiovascular complications and death occurred within 30 days in 28 (19.9%) and 20 (14.2%) patients, respectively. The risk predictors were: age, obesity, stroke, poor functional capacity, altered scintigraphy, surgery of the aorta, and troponin change. The scores RCRI and VSG-CRI had area under the curve of 0.635 and 0.639 for early cardiovascular complications, and 0.562 and 0.610 for death in 30 days.Conclusion:In this small and selected group of patients undergoing arterial vascular surgery, the incidence of adverse events was elevated. The risk assessment indices RCRI and VSG-CRI did not perform well for complications within 30 days.

Charakterisierung eines Bindungspartners von CHL1 und Analyse der Morphologie und des Verhaltens bei CHL1-defizienten, NrCAM-defizienten und CHL1/NrCAM-doppeldefizienten Mäusen

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2008

Einfluss des Hitzeschockproteins Hsc70 und des Raf Kinase Inhibitor Proteins RKIP auf den zellulären Transport und die Aktivität des [my]-Opioidrezeptors

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2008

Modulation des kanonischen Wnt/[Beta]-Catenin-Signalweges in der Helicobacter pylori-Infektion

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2010

Rolle des Vaskulären Endothelialen Wachstumsfaktors in der Meniskusheilung : eine experimentelle Studie am Tiermodell

Magdeburg, Univ., Medizin. Fakultät, Diss., 2004

Akzeptanz kosmetischer Körperkorrekturen und Prävalenz Körperdysmorpher Störungen bei Internetnutzern

Magdeburg, Univ., Med. Fak., Diss., 2010

Hörscreening von Neugeborenen : Ergebnisse der Früherfassung kindlicher Hörstörungen in den Jahren 2001-2007 am Krankenhaus Halberstadt

Magdeburg, Univ., Medizin. Fakultät, Diss., 2009

Vergleichende Untersuchungen zur Krafteinleitung in das proximale Femur bei Hüftendoprothesen mit unterschiedlichem Design

Magdeburg, Univ., Medizin. Fakultät, Diss., 2008

Charakterisierung einer inhibitor-insensitiven Trypsinaktivität bei experimenteller akuter Pankreatitis der Maus

Magdeburg, Univ., Medizin. Fakultät, Diss., 2010

Port-Katheter-Systeme in der Gynäkologie : eine Langzeituntersuchung zu Komplikationen und Risikofaktoren, Patientenzufriedenheit und Spülintervallen

Magdeburg, Univ., Med. Fak., Diss., 2011