Parallel Computation of 3D Morse-Smale Complexes

The Morse-Smale complex is a topological structure that captures the behavior of the gradient of a scalar function on a manifold. This paper discusses scalable techniques to compute the Morse-Smale complex of scalar functions defined on large three-dimensional structured grids. Computing the Morse-Smale complex of three-dimensional domains is challenging as compared to two-dimensional domains because of the non-trivial structure introduced by the two types of saddle criticalities. We present a parallel shared-memory algorithm to compute the Morse-Smale complex based on Forman's discrete Morse theory. The algorithm achieves scalability via synergistic use of the CPU and the GPU. We first prove that the discrete gradient on the domain can be computed independently for each cell and hence can be implemented on the GPU. Second, we describe a two-step graph traversal algorithm to compute the 1-saddle-2-saddle connections efficiently and in parallel on the CPU. Simultaneously, the extremasaddle connections are computed using a tree traversal algorithm on the GPU.

Understanding the role of domain-domain linkers in the spatial orientation of domains in multi-domain proteins

Inter-domain linkers (IDLs)' bridge flanking domains and support inter-domain communication in multi-domain proteins. Their sequence and conformational preferences enable them to carry out varied functions. They also provide sufficient flexibility to facilitate domain motions and, in conjunction with the interacting interfaces, they also regulate the inter-domain geometry (IDG). In spite of the basic intuitive understanding of the inter-domain orientations with respect to linker conformations and interfaces, we still do not entirely understand the precise relationship among the three. We show that IDG is evolutionarily well conserved and is constrained by the domain-domain interface interactions. The IDLs modulate the interactions by varying their lengths, conformations and local structure, thereby affecting the overall IDG. Results of our analysis provide guidelines in modelling of multi-domain proteins from the tertiary structures of constituent domain components.

Timer-Based Distributed Node Selection Scheme Exploiting Power Control and Capture

Opportunistic selection in multi-node wireless systems improves system performance by selecting the ``best'' node and by using it for data transmission. In these systems, each node has a real-valued local metric, which is a measure of its ability to improve system performance. Our goal is to identify the best node, which has the largest metric. We propose, analyze, and optimize a new distributed, yet simple, node selection scheme that combines the timer scheme with power control. In it, each node sets a timer and transmit power level as a function of its metric. The power control is designed such that the best node is captured even if. other nodes simultaneously transmit with it. We develop several structural properties about the optimal metric-to-timer-and-power mapping, which maximizes the probability of selecting the best node. These significantly reduce the computational complexity of finding the optimal mapping and yield valuable insights about it. We show that the proposed scheme is scalable and significantly outperforms the conventional timer scheme. We investigate the effect of. and the number of receive power levels. Furthermore, we find that the practical peak power constraint has a negligible impact on the performance of the scheme.

Microorganismos benéficos de montaña como bioestimulantes y probióticos contribuyentes al bienestar animal

Nicaragua a pesar de ser un país agropecuario presenta deficiencias en dicho sector, especialmente en el área de Bioseguridad en granjas porcinas y Bioestimulantes en cerdos, esta problemática se agudiza por la falta de conocimiento de la medicina alternativa, siendo esta la que estudia los microorganismos benéficos de montaña, por lo que se seleccionó la granja porcina UNA-DIPRO para realizar la presente investigación. Los objetivos fueron producir un complemento alimenticio probiótico y bioestimulante de uso veterinario , a través de un sistema artesanal administrado de forma oral, identificar los efectos de los microorganismos y comprobar su viabilidad. La metodología implementada fue un DCA con 5 repeticiones, 2 tratamientos, el período experimental duro 61 días, en donde a uno de estos grupos se le administró los Microorganismos Benéficos de Montaña sustituyéndose este por el 10% de concentrado y el otro no. Las variables evaluadas fueron: peso vivo, GMD, conversión alimenticia y costos en C$/kg. Los resultados obtenidos en base al análisis estadístico fueron que ninguna de las variables evaluadas arrojó diferencias significativas entre los dos grupos aunque la media de los pesos fue mayor a partir del segundo pesaje para el grupo testigo; la relación del consumo de alimento para el segundo mes fue menor para el grupo tratado; en el caso de la GMD el grupo con tratamiento mejoró del primer al segundo mes, la conversión en el primer mes el grupo testigo se comportó mejor que el grupo tratado, pero en el segundo mes fue lo contrario y la relación de costos con respecto al peso fue más barata en el grupo tratado. Se concluyó que es factible la elaboración de un cultivo de Microorganismos Benéficos Montaña de forma artesanal siendo viable en la producción porcina. Identificándose precocidad del libido sexual, se comprobó el efecto probiótico de los Microorganismos Benéficos Montaña y no hubo diferencias significativas en los análisis estadísticos en las variables.

Parameter Estimation for Hidden Markov Models with Intractable Likelihoods

Approximate Bayesian computation (ABC) is a popular technique for analysing data for complex models where the likelihood function is intractable. It involves using simulation from the model to approximate the likelihood, with this approximate likelihood then being used to construct an approximate posterior. In this paper, we consider methods that estimate the parameters by maximizing the approximate likelihood used in ABC. We give a theoretical analysis of the asymptotic properties of the resulting estimator. In particular, we derive results analogous to those of consistency and asymptotic normality for standard maximum likelihood estimation. We also discuss how sequential Monte Carlo methods provide a natural method for implementing our likelihood-based ABC procedures.

形成人工血栓的Chandler圆环内的流动分析

本文应用流体力学方法对Chandler 圆环内人工血栓形成的流动情况进行了细致分析。结果表明,形成血栓的下弯月面附近是一个既有迴流,又有二次流的区域,而且迴流的中心主流冲击着弯月面,为颗粒的聚集提供了有利的条件。本文对分析与血液流动有关的人工脏器和体内血栓形成的机理有一定的价值。

Recursos no processo penal

Consultoria Legislativa - Área II - Direito Civil e Processual Civil, Direito Penal e Processual Penal, de Família, do Autor, de Sucessões, Internacional Privado.

Dynamic Inefficiency in an Overlapping Generation Economy with Pollution and Health Costs

Revised 2008-08.-- Published as an article in: Journal of Public Economic Theory (2008), 10(4), 563-594.

Labor Market Assimilation of Recent Immigrants in Spain

Revised: 2006-11.-- Published as an article in: British Journal of Industrial Relations, June 2007, vol. 45, issue 2, pp. 257-284.

Internationalisation, multilingualism and English-medium instruction: the teacher's perspective

[EN]In the newEuropean higher education space, Universities in Europe are exhorted to cultivate and develop multilingualism. The European Commission’s 2004–2006 action plan for promoting language learning and diversity speaks of the need to build an environment which is favourable to languages. Yet reality indicates that it is English which reigns supreme and has become the main foreign language used as means of instruction at European universities. Internationalisation has played a key role in this process, becoming one of the main drivers of the linguistic hegemony exerted by English. In this paper we examine the opinions of teaching staff involved in English-medium instruction, from pedagogical ecologyof-language and personal viewpoints. Data were gathered using group discussion. The study was conducted at a multilingual Spanish university where majority (Spanish), minority (Basque) and foreign (English) languages coexist, resulting in some unavoidable linguistic strains. The implications for English-medium instruction are discussed at the end of this paper.

石门揭煤突出过程的数值模拟研究

运用岩石破裂过程分析PFPA2D系统,对急倾斜含瓦斯煤层中的石门揭煤突出过程进行了数值模拟研究。模拟结果再现了含瓦斯岩中裂纹的萌生、扩展、贯通直至煤岩抛出的突出全过程,并通过含瓦斯煤岩变形、破裂过程中的应力场演化说明了地应力、瓦斯压力以及煤体力学性质对诱发突出的综合作用。