Eine Ode Wolf Heidenheims aus dem Jahre 1795

L. Lewinsky

Mus Hs 1913b - Prends cette rose aimable comme toi : ode de Ronsard ; Wien, im März 1869

J. St.

Georg Friedrich Händel nach dem Stich aus dem Originaldruck seiner Cäcilien-Ode "Das Alexanderfest" 1738

Signatur des Originals: S 36/F08743

Ludwig van Beethoven, Brustbild - Liedanfang: Ludwig van Beethoven: Ode an die Freude

Signatur des Originals: S 36/F12355

Ode Sr. des Königs von Sachsen Friedrich August des Ersten Majestät : am Ersten Neujahrstage nach Seiner Erhebung zur Königswürde

allunterthänigst überreicht von den Aeltesten und Deputirten im Namen der Israelitischen Gemeinde allhier

Ode dem verehrten Ober-Büchsenmeister Anastasius : am 27. Februar 1820

ehrfurchtsvoll geweiht von Wigand

Retrospective assesment of the levonorgestrel intrauterine device to treat complex atypical hyperplasia and early endometrioid endometrial cancer

Objective: The primary objective of this project was to describe the efficacy of the Levonorgestrel Intrauterine Device (LIUD) for treatment of Complex Endometrial Cancer (CAH) and Grade 1 Endometrial Cancer (G1EEC) in terms of rate of Complete Response (CR) and Partial Response (PR) after 6 months of therapy. Finally, we assessed if any clinical or pathologic features were associated with response to the LIUD. ^ Methods: This study was a retrospective case series designed to report the response rate of patients with CAH or G1EEC treated with LIUD therapy. In addition, this study has a laboratory component to assess molecular predictors of response to LIUD therapy. Retrospective data already collected from patients diagnosed with CAH or EEC grade 1 and treated with LIUD therapy at MD Anderson Cancer Center (MDACC) were used for this study. Patients from all ethnic and race groups were included. A Complete Response (CR) was defined in patients diagnosed with CAH if pathologic report at 6 months demonstrated either no evidence of hyperplasia or no atypia in the setting of simple or complex hyperplasia. Partial Response (PR) was recorded if disease downgraded to only CAH from G1EEC. No Response (NR) was recorded if pathologic report demonstrates no change (Stable Disease, SD) or progression to cancer (Progressive Disease, PD). We calculated the proportion of patients with complete response to LIUD therapy with 95% confidence interval. We compared the response rates (CR/PR vs NR) by obesity status (Obese if BMI > 40 kg/m2 vs non-obese if BMI <= 40 kg/m2) as well as other clinical and pathologic factors, such as age, uterine size (median size), and presence of exogenous progesterone effect. ^ Results: There were 39 patients diagnosed with either CAH or G1EEC treated with the LIUD. Of 39 patients, 12 did not have pathological results of biopsy at 6months time period. Of 27 evaluable patients, 17 were diagnosed with CAH and 10 with G1EEC. Overall response rate (RR) was 78% (95% CI = 62-94%) at 6 months, 18 patients had CR (4 in G1EEC; 14 in CAH), 3 patients had PR (3 in G1EEC), 3 had SD (1 in CAH; 2 in G1EEC), 3 had PD (2 in CAH; 1 in G1EEC). After histology stratification, RR at 6 months was 82.35% (14/17; 95%CI = 67.4-97.3%) in CAH and 70% (7/10; 95% CI = 41-98.4%) in G1EEC. ^ There was no difference in response (R) and no response (NR) based on BMI (p=0.56). He observed a trend showing association between age with response (p=0.1). There was no association between uterine size and response to therapy (p=0.17). We recorded strong association between exogenous progesterone effect and response. ^ Conclusion: LIUD therapy for the treatment of CAH and G1EEC may be effective and safe. Presence of exogenous progesterone effect may predict the response to LIUD therapy at earlier time points. There is need of further studies with larger sample size to explore the relationship of response with other clinical and pathologic factors^

El Mito de Heracles en Baquílides. Su relevancia para el análisis de Traquinias de Sófocles

El mito de Heracles en los poemas de Baquílides no parece extremadamente profuso. Tradicionalmente se considera al ditirambo 16 como el poema más relevante del autor respecto del mito del héroe, particularmente en relación con Traquinias de Sófocles. Sin embargo, un análisis detenido del resto de las ocurrencias del mito en Baquílides demuestra que la influencia más trascendental del lírico excede los límites establecidos por el ditirambo. Los epinicios 5, 9 y 13, sumados a algunos fragmentos, representan una sorprendente fuente de originalidad, no sólo temática sino también formal. Es la intención del presente trabajo analizar dichos poemas en relación con Traquinias de Sófocles, de manera de determinar su influencia y/o relevancia para esta tragedia.

El Mito de Heracles en Baquílides. Su relevancia para el análisis de Traquinias de Sófocles

El mito de Heracles en los poemas de Baquílides no parece extremadamente profuso. Tradicionalmente se considera al ditirambo 16 como el poema más relevante del autor respecto del mito del héroe, particularmente en relación con Traquinias de Sófocles. Sin embargo, un análisis detenido del resto de las ocurrencias del mito en Baquílides demuestra que la influencia más trascendental del lírico excede los límites establecidos por el ditirambo. Los epinicios 5, 9 y 13, sumados a algunos fragmentos, representan una sorprendente fuente de originalidad, no sólo temática sino también formal. Es la intención del presente trabajo analizar dichos poemas en relación con Traquinias de Sófocles, de manera de determinar su influencia y/o relevancia para esta tragedia.

El Mito de Heracles en Baquílides. Su relevancia para el análisis de Traquinias de Sófocles

El mito de Heracles en los poemas de Baquílides no parece extremadamente profuso. Tradicionalmente se considera al ditirambo 16 como el poema más relevante del autor respecto del mito del héroe, particularmente en relación con Traquinias de Sófocles. Sin embargo, un análisis detenido del resto de las ocurrencias del mito en Baquílides demuestra que la influencia más trascendental del lírico excede los límites establecidos por el ditirambo. Los epinicios 5, 9 y 13, sumados a algunos fragmentos, representan una sorprendente fuente de originalidad, no sólo temática sino también formal. Es la intención del presente trabajo analizar dichos poemas en relación con Traquinias de Sófocles, de manera de determinar su influencia y/o relevancia para esta tragedia.

The atypical codon usage of the plant psbA gene may be the remnant of an ancestral bias

The psbA gene of the chloroplast genome has a codon usage that is unusual for plant chloroplast genes. In the present study the evolutionary status of this codon usage is tested by reconstructing putative ancestral psbA sequences to determine the pattern of change in codon bias during angiosperm divergence. It is shown that the codon biases of the ancestral genes are much stronger than all extant flowering plant psbA genes. This is related to previous work that demonstrated a significant increase in synonymous substitution in psbA relative to other chloroplast genes. It is suggested, based on the two lines of evidence, that the codon bias of this gene currently is not being maintained by selection. Rather, the atypical codon bias simply may be a remnant of an ancestral codon bias that now is being degraded by the mutation bias of the chloroplast genome, in other words, that the psbA gene is not at equilibrium. A model for the evolution of selective pressure on the codon usage of plant chloroplast genes is discussed.

Chloroplast small heat shock proteins: Evidence for atypical evolution of an organelle-localized protein

Knowledge of the origin and evolution of gene families is critical to our understanding of the evolution of protein function. To gain a detailed understanding of the evolution of the small heat shock proteins (sHSPs) in plants, we have examined the evolutionary history of the chloroplast (CP)-localized sHSPs. Previously, these nuclear-encoded CP proteins had been identified only from angiosperms. This study reveals the presence of the CP sHSPs in a moss, Funaria hygrometrica. Two clones for CP sHSPs were isolated from a F. hygrometrica heat shock cDNA library that represent two distinct CP sHSP genes. Our analysis of the CP sHSPs reveals unexpected evolutionary relationships and patterns of sequence conservation. Phylogenetic analysis of the CP sHSPs with other plant CP sHSPs and eukaryotic, archaeal, and bacterial sHSPs shows that the CP sHSPs are not closely related to the cyanobacterial sHSPs. Thus, they most likely evolved via gene duplication from a nuclear-encoded cytosolic sHSP and not via gene transfer from the CP endosymbiont. Previous sequence analysis had shown that all angiosperm CP sHSPs possess a methionine-rich region in the N-terminal domain. The primary sequence of this region is not highly conserved in the F. hygrometrica CP sHSPs. This lack of sequence conservation indicates that sometime in land plant evolution, after the divergence of mosses from the common ancestor of angiosperms but before the monocot–dicot divergence, there was a change in the selective constraints acting on the CP sHSPs.