Scitable - Learn Science with Nature Education

Scitable is an open online teaching/learning portal combining high quality educational articles authored by editors at NPG with technology-based community features to fuel a global exchange of scientific insights, teaching practices, and study resources. Scitable currently contains articles in the field of genetics, and is intended for college undergraduate faculty and students. Future plans involve extension of Scitable to other fields within the life sciences, as well as to other audiences. Scitable brings together a library of scientific overviews with a worldwide community of scientists, researchers, teachers and students. Nature Education is a new division of Nature Publishing Group devoted to facilitating high quality, innovative, accessible science education in all countries of the world.

El impacto de los clusters basados en tecnología en el desarrollo regional: el caso del tecnopolo Futuroscope de Gran Poitiers

Un gran número de reconocidas ciudades en el mundo han llegado a niveles excepcionalesde desarrollo económico y social apalancadas por innovaciones de punta. Para laregión de Poitou-Charentes, en Francia, la presencia del parque de atracciones Futuroscopeen la ciudad de Poitiers se ha convertido en una importante atracción turística que actualmente propone una incógnita: ¿es esta infraestructura suficiente para considerar elGrand Technopole de Poitiers como un exitoso cluster de alta tecnología?Para conseguir las condiciones que permitan consolidar este cluster de alta tecnología, laregión debe tener la posibilidad de articular, gestionar y gobernar agresivas estrategias deinnovación.Con base en los resultados de un estudio sobre varias ciudades innovadoras de todo elmundo, se identificaron mecanismos básicos que permiten romper con los paradigmas convencionales del crecimiento, por medio de innovaciones revolucionarias que permitentener rendimientos de clase mundial, una marca de prestigio global y el estatus de polo éxitosode innovación tecnológica. Los resultados obtenidos muestran las características delos tecnopolos existentes, que deben de potencializarse para conseguir un posicionamiento de clase mundial para la región.

ARTINTEC S.A.S.: propuestas interactivas con contenido educativo

ArtInTec es una organización creativa que ofrece servicios complementarios de apoyo pedagógico mediante instalaciones artísticas que integran arte y tecnología, unión que permite abarcar tres conceptos fundamentales: interactividad, lograda a través de herramientas tecnológicas convencionales y no convencionales; experiencias cognitivas significativas, mediante la generación de procesos de aprendizaje innovadores que permitan la construcción de saberes de trascendencia, y desarrollo de contenidos de diferentes temáticas que fortalezcan el aprendizaje. En su primera etapa, ArtInTec estará enfocada en el diseño, producción, comercialización, divulgación y venta de servicios transversales de apoyo pedagógico que impliquen la intermediación del arte y la tecnología, partiendo del concepto de instalación artística como género del arte contemporáneo que utiliza directamente el espacio de exposición como escenario para ser transitado por el espectador, logrando así una experiencia interactiva. Los tres servicios comparten características que se constituyen como columna vertebral de su naturaleza: tienen un objetivo altamente pedagógico, las temáticas son desarrolladas previo consenso entre la institución y ArtInTec, su componente artístico es el hilo conductor de la experiencia y se desarrollan en las instalaciones de la institución contratante. A continuación se enuncia cada uno de los servicios ofrecidos: a. Taller asistido por nuevas tecnologías. b. Instalación interactiva en gran formato. c. Instalación interactiva para dispositivos móviles.

A teaching/learning support tool for introductory programming courses

In This work we present a Web-based tool developed with the aim of reinforcing teaching and learning of introductory programming courses. This tool provides support for teaching and learning. From the teacher's perspective the system introduces important gains with respect to the classical teaching methodology. It reinforces lecture and laboratory sessions, makes it possible to give personalized attention to the student, assesses the degree of participation of the students and most importantly, performs a continuous assessment of the student's progress. From the student's perspective it provides a learning framework, consisting in a help environment and a correction environment, which facilitates their personal work. With this tool students are more motivated to do programming

An automatic correction tool for relational database schemas

A Web-based tool developed to automatically correct relational database schemas is presented. This tool has been integrated into a more general e-learning platform and is used to reinforce teaching and learning on database courses. This platform assigns to each student a set of database problems selected from a common repository. The student has to design a relational database schema and enter it into the system through a user friendly interface specifically designed for it. The correction tool corrects the design and shows detected errors. The student has the chance to correct them and send a new solution. These steps can be repeated as many times as required until a correct solution is obtained. Currently, this system is being used in different introductory database courses at the University of Girona with very promising results

Key competences in the new ventures: a model for evaluating

This research studies from an internal view based on the Competency-Based Perspective (CBP), key organizational competencies developed for small new business. CBP is chosen in an attempt to explain the differences characterizing the closed companies from the consolidated ones. The main contribution of this paper is the definition of a set of key organizational competencies for new ventures from services and low technology based sectors. Using the classification proposed by [1] and a review of the entrepreneurship literature, the main competencies were defined and classified as: managerial, input-based, transformation-based, and output-based competencies. The proposed model for evaluating new ventures organizational competence is tested by means of Structural Equation

Integració 3D de detectors de píxels híbrids

La miniaturització de la industria microelectrònica és un fet del tot inqüestionables i la tecnologia CMOS no n'és una excepció. En conseqüència la comunitat científica s'ha plantejat dos grans reptes: En primer lloc portar la tecnologia CMOS el més lluny possible ('Beyond CMOS') tot desenvolupant sistemes d'altes prestacions com microprocessadors, micro - nanosistemes o bé sistemes de píxels. I en segon lloc encetar una nova generació electrònica basada en tecnologies totalment diferents dins l'àmbit de les Nanotecnologies. Tots aquests avanços exigeixen una recerca i innovació constant en la resta d'àrees complementaries com són les d'encapsulat. L'encapsulat ha de satisfer bàsicament tres funcions: Interfície elèctrica del sistema amb l'exterior, Proporcionar un suport mecànic al sistema i Proporcionar un camí de dissipació de calor. Per tant, si tenim en compte que la majoria d'aquests dispositius d'altes prestacions demanden un alt nombre d'entrades i sortides, els mòduls multixip (MCMs) i la tecnologia flip chip es presenten com una solució molt interessant per aquests tipus de dispositiu. L'objectiu d'aquesta tesi és la de desenvolupar una tecnologia de mòduls multixip basada en interconnexions flip chip per a la integració de detectors de píxels híbrids, que inclou: 1) El desenvolupament d'una tecnologia de bumping basada en bumps de soldadura Sn/Ag eutèctics dipositats per electrodeposició amb un pitch de 50µm, i 2) El desenvolupament d'una tecnologia de vies d'or en silici que permet interconnectar i apilar xips verticalment (3D packaging) amb un pitch de 100µm. Finalment aquesta alta capacitat d'interconnexió dels encapsulats flip chip ha permès que sistemes de píxels tradicionalment monolítics puguin evolucionar cap a sistemes híbrids més compactes i complexes, i que en aquesta tesi s'ha vist reflectit transferint la tecnologia desenvolupada al camp de la física d'altes energies, en concret implantant el sistema de bump bonding d'un mamògraf digital. Addicionalment s'ha implantat també un dispositiu detector híbrid modular per a la reconstrucció d'imatges 3D en temps real, que ha donat lloc a una patent.

SME’s Alliance Dynamics in the Mobile Marketing Industry

This paper presents a case study of the two similar sized, new, technology-based firms acting as alliance partners in the Mobile commerce industry. The analysis describes how the alliance dynamics in our case study relate to seminal research in the field of business alliance formation. Contrary to the established predictions we find that the negative influence on alliance performance described as a consequence of the dissolved routinized alliance pattern by seminal authors is not present. At the same time, the case study shows that internalization of complementary assets does not by necessity result in dissolution of the business alliance as argued from a resource and competence based perspective.

Supporting multi-organisational collaborative groups in the public sector

In this paper, the issues that arise in multi-organisational collaborative groups (MOCGs) in the public sector are discussed and how a technology-based group support system (GSS) could assist individuals within these groups. MOCGs are commonly used in the public sector to find solutions to multifaceted social problems. Finding solutions for such problems is difficult because their scope is outside the boundary of a single government agency. The standard approach to solving such problems is collaborative involving a diverse range of stakeholders. Collaborative working can be advantageous but it also introduces its own pressures. Conflicts can arise due to the multiple contexts and goals of group members and the organisations that they represent. Trust, communication and a shared interface are crucial to making any significant progress. A GSS could support these elements.

Using historical lesion volume data in the design of a new phase II clinical trial in acute stroke

Background and Purpose-Clinical research into the treatment of acute stroke is complicated, is costly, and has often been unsuccessful. Developments in imaging technology based on computed tomography and magnetic resonance imaging scans offer opportunities for screening experimental therapies during phase II testing so as to deliver only the most promising interventions to phase III. We discuss the design and the appropriate sample size for phase II studies in stroke based on lesion volume. Methods-Determination of the relation between analyses of lesion volumes and of neurologic outcomes is illustrated using data from placebo trial patients from the Virtual International Stroke Trials Archive. The size of an effect on lesion volume that would lead to a clinically relevant treatment effect in terms of a measure, such as modified Rankin score (mRS), is found. The sample size to detect that magnitude of effect on lesion volume is then calculated. Simulation is used to evaluate different criteria for proceeding from phase II to phase III. Results-The odds ratios for mRS correspond roughly to the square root of odds ratios for lesion volume, implying that for equivalent power specifications, sample sizes based on lesion volumes should be about one fourth of those based on mRS. Relaxation of power requirements, appropriate for phase II, lead to further sample size reductions. For example, a phase III trial comparing a novel treatment with placebo with a total sample size of 1518 patients might be motivated from a phase II trial of 126 patients comparing the same 2 treatment arms. Discussion-Definitive phase III trials in stroke should aim to demonstrate significant effects of treatment on clinical outcomes. However, more direct outcomes such as lesion volume can be useful in phase II for determining whether such phase III trials should be undertaken in the first place. (Stroke. 2009;40:1347-1352.)

Integrated optics for nulling interferometry in the thermal infrared

Modal filtering is based on the capability of single-mode waveguides to transmit only one complex amplitude function to eliminate virtually any perturbation of the interfering wavefronts, thus making very high rejection ratios possible in a nulling interferometer. In the present paper we focus on the progress of Integrated Optics in the thermal infrared [6-20 mu m] range, one of the two candidate technologies for the fabrication of Modal Filters, together with fiber optics. In conclusion of the European Space Agency's (ESA) "Integrated Optics for Darwin" activity, etched layers of clialcogenide material deposited on chalcogenide glass substrates was selected among four candidates as the technology with the best potential to simultaneously meet the filtering efficiency, absolute and spectral transmission, and beam coupling requirements. ESA's new "Integrated Optics" activity started at mid-2007 with the purpose of improving the technology until compliant prototypes can be manufactured and validated, expectedly by the end of 2009. The present paper aims at introducing the project and the components requirements and functions. The selected materials and preliminary designs, as well as the experimental validation logic and test benches are presented. More details are provided on the progress of the main technology: vacuum deposition in the co-evaporation mode and subsequent etching of chalcogenide layers. In addition., preliminary investigations of an alternative technology based on burying a chalcogenide optical fiber core into a chalcogenide substrate are presented. Specific developments of anti-reflective solutions designed for the mitigation of Fresnel losses at the input and output surface of the components are also introduced.

A multi-agent system for pervasive healthcare

Wireless technology based pervasive healthcare has been proposed in many applications such as disease management and accident prevention for cost saving and promoting citizen’s wellbeing. However, the emphasis so far is on the artefacts with limited attentions to guiding the development of an effective and efficient solution for pervasive healthcare. Therefore, this paper aims to propose a framework of multi-agent systems design for pervasive healthcare by adopting the concept of pervasive informatics and using the methods of organisational semiotics. The proposed multi-agent system for pervasive healthcare utilises sensory information to support healthcare professionals for providing appropriate care. The key contributions contain theoretical aspect and practical aspect. In theory, this paper articulates the information interactions between the pervasive healthcare environment and stakeholders by using the methods of organisational semiotics; in practice, the proposed framework improves the healthcare quality by providing appropriate medical attentions when and as needed. In this paper, both systems and functional architecture of the multi-agent system are elaborated with the use of wireless technologies such as RFID and wireless sensor networks. The future study will focus on the implementation of the proposed framework.

Aprendizagem e desenvolvimento organizacional : uma experiência com o modelo da quinta disciplina

A complexidade e pressão que o contexto atual de mudança tem gerado para as organizações, tem exigido delas habilidades diferentes daquelas privilegiadas na era das organizações mecanicistas. A aprendizagem tornou-se uma das habilidades-chave para sobrevivência e desenvolvimento das organizações modernas. Alguns modelos gerenciais apresentam-se visando melhorar as capacidades de aprendizagem das organizações. Alguns tratam da questão estrutural, outros da questão comportamental. Um desses vem recebendo interesse especial, pela sua ênfase no elemento humano nas organizações: o modelo da Quinta Disciplina, de Peter M. Senge e seus colegas do M.I.T. - Massachussets Institute of Technology. Por ter como pressuposto que as organizações são em essência produto do pensar e interagir dos seus membros, sugere que a sua transformação passa por mudanças fundamentais nas formas como as pessoas pensam e interagem. Todavia, observa-se que a prática educacional e experiencial do modelo não tem levado em consideração alguns dos seus aspectos fundamentais. Desta forma, este estudo exploratório pretende descrever e avaliar as reações à aplicação do modelo numa realidade organizacional como forma de obter insights úteis para a prática e pesquisa em organizações, uma vez levando em consideração estes aspectos fundamentais. Como resultado, este trabalho descreve e analisa a experiência à luz das cinco disciplinas, unidades básicas do modelo, dando ênfase especial ao pensamento sistêmico, e descreve e analisa a experiência à luz de algumas variáveis, processos e dimensões-chave do estudo das organizações que apresentaram-se relevantes dentro do trabalho.

Parques e incubadoras de empresas de base tecnológica

The main purpose of this paper is to give a wide vision about science parks, technology parks, incubators and technology based firms and to show the Brazilian experience on these subjects. This kind of enterprises is considered one of the most important local and regional development instruments in the present. They demand actions to strengthen the links between firms, R&D centers, universities and governments, especially, local governments. Furthermore, the venture capital firms have an important role to play in these new approach to further the regional and local development through technological innovations. This paper emphasizes the importance of the venture capital and the strategic alliances to support this new approaches and shows that the lack of these instruments in Brazilian environment is one of the main problem of these technology based enterprises.

Gestão de transferência de inovações tecnológicas para empresas do setor produtivo: complexidade no relacionamento entre organizações de culturas diferentes

The motivation of this study is based on the expectation of understanding, at least in part, the reason why the brazilian academic production ¿ which is among the largest if compared to the developing countries, has not been translated in a useful way into concrete technology transference for the production sector. The supposition that different cultures and subcultures, in terms of values, behavior, practices among organizations and groups of selected actors involved in that process,- which is the central problem of this study, and peculiar to the technology context, has elected that relationship process the object of this research this study theoretical fundaments rely on culture and technology to analyze the subcultures which manifest themselves through the typified groups of researchers, in the public organizations, small scale employers, acting on technology based companies in the private sector (ebts) and mediators. Who also act in the process the preliminary step was the case study. Several qualitative methods an procedures were used. And the investigation has advanced toward interacting interviews, at the end added by the focal group method. The conclusions reject the existence of incompatibility among the subject groups points of view, however, points out some divergent values, the presence of mutual stereotypes and also confirms the supposition that the research platform is strongly influenced by the financial factor. Although, the study reveals that the presence of common objectives which lay behind the cited divergences make possible to present a core of practical suggestions to implement the studied relationships for the benefit of the production sector as well. The peculiarities perceived while dealing with that singular context suggest futures research to clarify possible new and obscure areas in that complex relationships.