Effects of elevated atmospheric CO2 and O3 on wood density, antomical proerties and decomposition of Northern Hardwoods

Anthropogenic activities continue to drive atmospheric CO2 and O3 concentrations to levels higher than during the pre-industrial era. Accumulating evidence indicates that both elevated CO2 and elevated O3 could modify the quantity and biochemistry of woody plant biomass. Anatomical properties of woody plants are largely influenced by the activity of the cambium and the growth characteristics of wood cells, which are in turn influenced by a range of environmental factors. Hence, alterations in the concentrations of atmospheric CO2 and / or O3 could also impact wood anatomical properties. Many fungi derive their metabolic resources for growth from plant litter, including woody tissue, and therefore modifications in the quantity, biochemistry and anatomical properties of woody plants in response to elevated CO2 and / or O3 could impact the community of wood-decaying fungi and rates of wood decomposition. Consequently carbon and nutrient cycling and productivity of terrestrial ecosystem could also be impacted. Alterations in wood structure and biochemistry of woody plants could also impact wood density and subsequently impact wood quality. This dissertation examined the long term effects of elevated CO2 and / or O3 on wood anatomical properties, wood density, wood-decaying fungi and wood decomposition of northern hardwood tree species at the Aspen Free-Air CO2 and O3 Enrichment (Aspen FACE) project, near Rhinelander, WI, USA. Anatomical properties of wood varied significantly with species and aspen genotypes and radial position within the stem. Elevated CO2 did not have significant effects on wood anatomical properties in trembling aspen, paper birch or sugar maple, except for marginally increasing (P < 0.1) the number of vessels per square millimeter. Elevated O3 marginally or significantly altered vessel lumen diameter, cell wall area and vessel lumen area proportions depending on species and radial position. In line with the modifications in the anatomical properties, elevated CO2 and O3, alone, significantly modified wood density but effects were species and / or genotype specific. However, the effects of elevated CO2 and O3, alone, on wood anatomical properties and density were ameliorated when in combination. Wood species had a much greater impact on the wood-decaying fungal community and initial wood decomposition rate than did growth or decomposition of wood in elevated CO2 and / or O3. Polyporales, Agaricales, and Russulales were the dominant orders of fungi isolated. Based on the current results, future higher levels of CO2 and O3 may have moderate effects on wood quality of northern hardwoods, but for utilization purposes these may not be considered significant. However, wood-decaying fungal community composition and decomposition of northern hardwoods may be altered via shifts in species and / or genotype composition under future higher levels of CO2 and O3.

MITEP: REFLECTIVE JOURNEY

This research looks at the use of the Interactive Student Notebook (ISN) in the math classroom and the impact on student achievement as part of the MiTEP program. A reflective critical analysis of the MiTEP program discusses impact on teacher pedagogy, leadership, and connections to people and resources. The purpose of the study stemmed from the lack of student retention, poor organizational skills, and the students’ inability to demonstrate college readiness skills such as how to study, completing homework, and thinking independently. Motivation also stemmed from teacher frustration. The research was conducted at Linden Grove Middle School in Kalamazoo Michigan in a strategic math class. Twenty-two sixth graders, thirty-two seventh graders, and forty eighth graders were part of the study.Students were given the Strategic Math Inventory (SMI) test in week 1 of the class and again at the end of a 12 week marking period. Students participated in an attitude survey to record their feelings about the use of the ISN in the strategic math classroom. The data compared the control group (the previous year’s [2012-2013] growth data) to the experimental group, the current year’s (2013-2014) growth data. Both groups were statistically similar in that the mean average was about a 4th grade level equivalency and the groups had similar numbers of grade level students. The significant findings were in the amount of growth made using the ISN. The control group started with a mean average of 586.6 and ended with a mean average of 697.1, making about one year’s growth from a 4th to a 5th grade level equivalency. The experimental group started with a mean average of 585.2 and ended with a mean average of 744.2, making about two years growth from a 4th to a 6th grade level equivalency. This is double the growth of the control group. The Cohen’s test resulted in a score of 0.311 which describes that the teaching method, the use of the ISN in the math classroom had a medium impact on student growth.

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia.

A pivotal mediator of actin dynamics is the protein cofilin, which promotes filament severing and depolymerization, facilitating the breakdown of existing filaments, and the enhancement of filament growth from newly created barbed ends. It does so in concert with actin interacting protein 1 (Aip1), which serves to accelerate cofilin's activity. While progress has been made in understanding its biochemical functions, the physiologic processes the cofilin/Aip1 complex regulates, particularly in higher organisms, are yet to be determined. We have generated an allelic series for WD40 repeat protein 1 (Wdr1), the mammalian homolog of Aip1, and report that reductions in Wdr1 function produce a dramatic phenotype gradient. While severe loss of function at the Wdr1 locus causes embryonic lethality, macrothrombocytopenia and autoinflammatory disease develop in mice carrying hypomorphic alleles. Macrothrombocytopenia is the result of megakaryocyte maturation defects, which lead to a failure of normal platelet shedding. Autoinflammatory disease, which is bone marrow-derived yet nonlymphoid in origin, is characterized by a massive infiltration of neutrophils into inflammatory lesions. Cytoskeletal responses are impaired in Wdr1 mutant neutrophils. These studies establish an essential requirement for Wdr1 in megakaryocytes and neutrophils, indicating that cofilin-mediated actin dynamics are critically important to the development and function of both cell types.

Virus-like particle-mediated intracellular delivery of mRNA cap analog with in vivo activity against hepatocellular carcinoma.

UNLABELLED Adenovirus dodecahedron (Dd), a nanoparticulate proteinaceous biodegradable virus-like particle (VLP), was used as a vector for delivery of an oncogene inhibitor to hepatocellular carcinoma (HCC) rat orthotopic model. Initiation factor eIF4E is an oncogene with elevated expression in human cancers. Cell-impermeant eIF4E inhibitor, cap structure analog (cap) and anti-cancer antibiotic doxorubicin (Dox) were delivered as Dd conjugates. Dd-cap and Dd-dox inhibited cancer cell culture proliferation up to 50 and 84%, respectively, while with free Dox similar results could be obtained only at a 5 times higher concentration. In animal HCC model the combination treatment of Dd-cap/Dd-dox caused 40% inhibition of tumor growth. Importantly, the level of two pro-oncogenes, eIF4E and c-myc, was significantly diminished in tumor sections of treated rats. Attachment to Dd, a virus-like particle, permitted the first demonstration of cap analog intracellular delivery and resulted in improved doxorubicin delivery leading to statistically significant inhibition of HCC tumor growth. FROM THE CLINICAL EDITOR Adenovirus dodecahedron, a nanoparticulate proteinaceous biodegradable virus-like particle was used in this study as a vector for the concomitant delivery of cap structure analog and doxorubicine to hepatocellular carcinoma in a rat model, resulting in significant inhibition of tumor growth.

The sleeper effect: Artifact or phenomenon—A brief comment on Bell et al. (2013)

OBJECTIVE: Bell, Marcus, and Goodlad (2013) recently conducted a meta-analysis of randomized controlled additive trials and found that adding an additional component to an existing treatment vis-à-vis the existing treatment produced larger effect sizes on targeted outcomes at 6-months follow-up than at termination, an effect they labeled as a sleeper effect. One of the limitations with Bell et al.'s detection of the sleeper effect was that they did not conduct a statistical test of the size of the effect at follow-up versus termination. METHOD: To statistically test if the differences of effect sizes between the additive conditions and the control conditions at follow-up differed from those at termination, we used a restricted maximum-likelihood random-effect model with known variances to conduct a multilevel longitudinal meta-analysis (k = 30). RESULTS: Although the small effects at termination detected by Bell et al. were replicated (ds = 0.17-0.23), none of the analyses of growth from termination to follow-up produced statistically significant effects (ds < 0.08; p > .20), and when asymmetry was considered using trim-and-fill procedure or the studies after 2000 were analyzed, magnitude of the sleeper effect was negligible (d = 0.00). CONCLUSION: There is no empirical evidence to support the sleeper effect.

The effects of benefit finding on athletes’ quality of adjustment to career termination

Retirement from elite sports requires athletes to cope with adjustments on an occupational, financial, physical, social or emotional level. Research on critical life events (e.g., Filipp & Aymanns, 2010) suggests that benefit finding, defined as “the process of deriving positive growth from adversity” (Cassidy et al., 2014), may have a positive impact on this transition. The present study examined the effects of benefit finding on the quality of adjustment to career termination in the short, middle and long term. Former Swiss elite athletes (N = 290) completed a written survey collecting information on a) their emotional reaction to career termination, b) the amount of adjustment in various respects, c) situational characteristics of their career termination, d) the duration and quality of the transition, and e) their subjective well-being. Using Latent Variable Modelling, finding benefit in career termination was found to have both a direct and an indirect effect on long-term well-being (γ=.18). It predicts favorable emotional reactions to career termination (γ = .53) and less adjustment (γ = -.38) which in turn shortens the transition duration (β = -.15 and β = .55, respectively) and quality (β = -.15), and finally augments well-being (β = .41). The data suggest that a focus on benefit finding in both crisis-prevention and crisis-coping interventions may prove useful to prevent crisis transitions.

Intervención judicial y contexto socio cultural : la puesta en marcha de un trabajo interdisciplinario "in situ"

Partiendo de una noción de acceso a la justicia, que no se restringe únicamente al acceso formal de los ciudadanos al sistema judicial y al adecuado ejercicio de derechos ante los Tribunales de Justicia, sino que también abarca la Prevención y Promoción de Derechos, la Solución Colaborativa de Conflictos, la Revisión y Propuesta de las Actuaciones Públicas mediante Acciones de Interés Público y Propuestas Legislativas; se implementaron, desde la Institución Judicial (Juzgado de Familia de Tupungato), acciones en el marco de buenas prácticas que se sustentas en tres ejes: Construcción de Ciudadanía, Desarrollo Humano Sustentable y Redes Sociales. Las mismas tienden a fortalecer las conexiones entre estructuras formales e informales de la comunidad, a fin de proveer efectivamente el Acceso a la Justicia a grupos que de otra manera podrían estar excluidos de ella y a la vez favorecer el empoderamiento de los grupos vulnerables en la búsqueda de soluciones a situaciones injustas en el ámbito de los procesos tramitan por ante los Juzgados de Familia. En dicho marco, el Juzgado referido puso en marcha un Juzgado Móvil que plantea una metodología de abordaje interdisciplinario, donde la intervención del Trabajador Social resulta relevante.

(Table 1) Stabile isotopes at DSDP Leg 55 Holes

Deep sea drilling on four seamounts in the Emperor Seamount chain revealed that Paleogene shallow-water carbonate sediments of the "bryozoan-algal" facies crown the basalt edifices. According to the biofacies model of Schlanger and Konishi (1966, 1975), this bryozoan- algal assemblage suggests that the seamounts formed in cooler, more northerly waters than those presently occupied by the island of Hawaii; i.e., the paleolatitudes of formation were greater than 20 °N. Moving southward toward the youngest member of the seamount chain, a facies gradient indicative of warmer waters was observed. This gradient is interpreted as a reflection of a northward shift in isotherms during the time span in which the seamounts were progressively formed (Savin et al., 1975). On all seamounts, sedimentation at the drilling sites occurred in a high-energy environment with water depths of approximately 20 meters. Early-stage carbonate diagenesis began in the phreatic zone in the presence of meteoric water, but proceeded after subsidence of the seamounts into intermediate sea waters, where the bulk, stable isotopic composition was determined. The subsidence into intermediate waters was rapid, and permitted establishment of an isotopic equilibrium which, like the facies gradient, reflects the northward shift in isotherms during the Paleogene. Calcite and zeolite cements comprise the later-stage diagenesis, and originated from solutions arising from the hydrolysis of the underlying basalt. In conclusion, the results of this study of the shallow-water carbonate sediments are not inconsistent with a paleolatitude of formation for Suiko Seamount (Site 433) of 26.9 ±3.5 °N, as determined by paleomagnetic measurements (Kono, 1980).

Respuesta al déficit hídrico en el crecimiento de forestales del bosque urbano de Mendoza : análisis comparativo en árboles jóvenes

El objetivo del trabajo fue evaluar la respuesta de plantas jóvenes de cuatro especies forestales urbanas a diferentes niveles de déficit hídrico. El ensayo se realizó en vivero, durante tres ciclos vegetativos, con plantas de Platanus x hispanica cv. acerifolia (plátano), Morus alba (morera), Fraxinus americana (fresno americano) y Acacia visco (visco). Los tratamientos de riego fueron: control (reposición del 100% transpirado); riego deficitario moderado (reposición del 66% transpirado) y riego deficitario severo (reposición del 33% transpirado). Las variables de respuesta evaluadas fueron altura, diámetro de tallos, área foliar y ancho de anillos de crecimiento. Las plantas bajo riego deficitario severo presentaron disminuciones en todos los parámetros de crecimiento considerados. Acacia visco resultó con crecimientos comparables al control, bajo riego deficitario equivalente al 66% del agua transpirada, con lo cual puede ser considerada especie de interés para forestaciones en condiciones de estrés hídrico moderado.

Geochemistry of DSDP Hole 83-504B minerals

Leg 83 of the Deep Sea Drilling Project has deepened Hole 504B to over 1 km into basement, 1350 m below the seafloor (BSF). The hole previously extended through 274.5 m of sediment and 561.5 m of pillow basalts altered at low temperature (< 100°C), to 836 m BSF. Leg 83 drilling penetrated an additional 10 m of pillows, a 209-m transition zone, and 295 m into a sheeted dike complex. Leg 83 basalts (836-1350 m BSF) generally contain superimposed greenschist and zeolite-facies mineral parageneses. Alteration of pillows and dikes from 836 to 898 m BSF occurred under reducing conditions at low water/rock ratios, and at temperatures probably greater than 100°C. Evolution of fluid composition resulted in the formation of (1) clay minerals, followed by (2) zeolites, anhydrite, and calcite. Alteration of basalts in the transition zone and dike sections (898-1350 m BSF) occurred in three basic stages, defined by the opening of fractures and the formation of characteristic secondary minerals. (1) Chlorite, actinolite, pyrite, albite, sphene, and minor quartz formed in veins and host basalts from partially reacted seawater (Mg-bearing, locally metal-and Si-enriched) at temperatures of at least 200-250°C. (2) Quartz, epidote, and sulfides formed in veins at temperatures of up to 380°C, from more evolved (Mg-depleted, metal-, Si-, and 18O-enriched) fluids. (3) The last stage is characterized by zeolite formation: (a) analcite and stilbite formed locally, possibly at temperatures less than 200°C followed by (b) formation of laumontite, heulàndite, scolecite, calcite, and prehnite from solutions depleted in Mg and enriched in Ca and 18O, at temperatures of up to 250°C. The presence of small amounts of anhydrite locally may be due to ingress of relatively unaltered seawater into the system during Stage 3. Alteration was controlled by the permeability of the crust and is characterized by generally incomplete recrystallization and replacement reactions among secondary minerals. Secondary mineralogy in the host basalts is strongly controlled by primary mineralogy. The alteration of Leg 83 basalts can be interpreted in terms of an evolving hydrothermal system, with (a) changes in solution composition because of reaction of seawater fluids with basalts at high temperatures; (b) variations in permeability caused by several stages of sealing and reopening of cracks; and (c) a general cooling of the system, caused either by the cooling of a magma chamber beneath the spreading center and/or the movement of the crust away from the heat source. The relationship of the high-temperature alteration in the transition zone and dike sections to the low-temperature alteration in the overlying pillow section remains uncertain.

Geochemistry of altered smectites

In basalts and volcanogenic sediments from the Indian Ocean, the successive stages of submarine alteration of volcanic rocks and glasses give rise to the incorporation or the relative increase of iron in smectite lattices. During the first stage, the Mg-smectites are the most abundant; they are occasionally associated with Al-smectites. Afterwards, they are gradually replaced by iron-rich smectites. The REE distribution follows the same trend as the mineralogical changes. During the f'trst stage of alteration, REE distribution in clay minerals is the same as in the fresh glasses but, when the iron-rich smectites increase, the Ce has a specific behaviour. The Ce shows a positive anomaly in iron-rich smectites formed early in palagonitized glasses, and a negative one in authigenic smectites formed later from solutions in equilibrium with seawater.

How has financial deepening affected poverty reduction in India? : empirical analysis using state-level panel data

This paper examines empirically whether financial deepening has contributed to poverty reduction in India. Using unbalanced panel data for 28 states and union territories between 1973 and 2004, we estimate models in which the poverty ratio is explained by financial deepening, controlling for international openness, inflation rate, and economic growth. From the dynamic generalised method of moments (GMM) estimation, we find that financial deepening and economic growth alleviate poverty, while international openness and the inflation rate have the opposite effect. These results are robust to changes in the poverty ratios in rural areas, urban areas, and the whole economy.

Public support for the deployment of next generation access networks-Common themes, methodological caveats and further research

Next generation telecommunications infrastructures are considered as a principal example of a new technology for sustainable economic growth. From their deployment it is expected that a wealth of innovations – hopefully converted into economic growth – new sources of employment and improved quality of life will result. In line with these prospects, public administrations at supranational, national, regional and local levels have encouraged the development of these new infrastructures. Moreover, in times of economic crisis, public assistance to deploy such networks encompasses the promise of placing a weak economy on the road to prosperity. However, such arguments and political claims clearly require rigorous assessment. In particular, any such assessment must adequately address the appropriate form of modelling that best captures key elements for identifiable progress from next generation access networks (NGAN).

An architectural model for software testing lesson learned systems

Software testing is a key aspect of software reliability and quality assurance in a context where software development constantly has to overcome mammoth challenges in a continuously changing environment. One of the characteristics of software testing is that it has a large intellectual capital component and can thus benefit from the use of the experience gained from past projects. Software testing can, then, potentially benefit from solutions provided by the knowledge management discipline. There are in fact a number of proposals concerning effective knowledge management related to several software engineering processes. Objective: We defend the use of a lesson learned system for software testing. The reason is that such a system is an effective knowledge management resource enabling testers and managers to take advantage of the experience locked away in the brains of the testers. To do this, the experience has to be gathered, disseminated and reused. Method: After analyzing the proposals for managing software testing experience, significant weaknesses have been detected in the current systems of this type. The architectural model proposed here for lesson learned systems is designed to try to avoid these weaknesses. This model (i) defines the structure of the software testing lessons learned; (ii) sets up procedures for lesson learned management; and (iii) supports the design of software tools to manage the lessons learned. Results: A different approach, based on the management of the lessons learned that software testing engineers gather from everyday experience, with two basic goals: usefulness and applicability. Conclusion: The architectural model proposed here lays the groundwork to overcome the obstacles to sharing and reusing experience gained in the software testing and test management. As such, it provides guidance for developing software testing lesson learned systems.

Caracterización de usuario y tráfico en la evolución de la banda ancha en España

El mundo de las telecomunicaciones evoluciona a gran velocidad, acorde con las necesidades de los usuarios. El crecimiento del número de servicios a través de las conexiones que actualmente utilizamos para conectarnos a Internet (Ej. IPTV) con elevados requerimientos de ancho de banda, que junto a los servicios de nuevo nacimiento (ej. OTT), contribuyen tanto al aumento de la necesidad de mayores velocidades de conexión de los usuarios como a la implantación de nuevos modelos de calidad de servicio. Las redes de datos de banda ancha (fija y móvil) actuales deben, por lo tanto, experimentar una profunda transformación para conseguir solventar de una forma eficiente los problemas y las necesidades de tráfico, pudiendo así absorber el progresivo incremento del ancho de banda, dejando las puertas abiertas a futuras mejoras. Y para ello las operadoras se nutrirán con la valiosa información de tráfico y usuario que les lleven a tomar las mejores decisiones de cara a que las transformaciones llevadas a cabo cubran exactamente lo que el usuario demanda de la forma más eficiente posible. Con estas premisas, surgieron las ideas que se plasmaron como objetivos del PFC : La idea de narrar el despliegue de la banda ancha en España desde sus orígenes hasta la actualidad, enfocando su crecimiento desde un punto de vista sociotecnológico. Dando continuidad al punto anterior, se persiguió la idea de conocer las herramientas sociales y tecnológicas a raíz de las cuales se pueda realizar una previsión del tráfico en las redes de las operadoras en un futuro cercano. La pretensión de mostrar las características de los usuarios de banda ancha y del tráfico de datos que generan, que son de carácter crítico para las operadoras en la elaboración de forma adecuada de la planificación de sus redes. La intención de revelar los procedimientos de las operadoras para que, una vez conocidas las características de sus usuarios, se puedan cumplir los requisitos demandados por los mismos: QoS y los indicadores clave de rendimiento (KPIs) Por otro lado, el nivel de detalle dado pretende adecuarse a un público que no tenga profundos conocimientos sobre la materia, y salvo partes bastante concretas, se puede catalogar este trabajo como de abierto al público en general. ABSTRACT. The world of telecommunications is evolving at high speed, according to the needs of users. The growing of services number through the connections that currently have been used to connect to the Internet (eg IPTV ) with high bandwidth requirements, which together with the new birth services (eg OTT ) contribute both to increased the need for higher connection speeds users and the implementation of new models of service quality. Data networks broadband (fixed and mobile ) today must , therefore, undergo a deep transformation to achieve an efficient solving problems and traffic needs, thus being able to absorb the gradual increase of bandwidth, leaving the door open to future improvements. And for that the operators will be nurtured with valuable information and user traffic that lead them to make better decisions in the face of the transformations carried out exactly meet the user demand for the most efficient possible way. With these assumptions, the ideas that emerged were expressed as PFC objectives : The idea of narrating the broadband deployment in Spain from its origins to the present, focusing its growth from a socio-technological approach. Continuing the previous point, it pursued the idea of knowing the social tools and technology as a result of which it can perform a traffic forecast operators networks in the near future. The attempt to show the characteristics of broadband users and data traffic they generate, which are mission critical for operators in developing adequately planning their networks. The intention to disclose procedures for operators, once known the characteristics of their users, it can meet the requirements demanded by them: QoS and key performance indicators (KPI). On the other hand, the level of detail given suit seeks an audience that does not have deep knowledge on the subject, unless quite specific parts, this work can be classified as open to the general public.