CARACTERÍSTICAS PSICOSSOCIAIS E DE PERSONALIDADE DE ADOLESCENTES INFRATORES EM CUMPRIMENTO DE MEDIDA SOCIOEDUCATIVA

Para atingir os objetivos propostos, ou seja, levantar e descrever indicadores socioculturais de uma amostra de adolescentes em cumprimento de medida socioeducativa, e descrever características psicológicas e de personalidade dos adolescentes infratores, num estudo que pesquisou adolescentes em cumprimento de medida socioeducativa. O trabalho foi realizado em duas as etapas: na primeira, os 47 adolescentes participaram de uma entrevista semidirigida; na segunda, dez desses adolescentes foram selecionados e submetidos a um instrumento projetivo para investigação de aspectos da personalidade: o “desenho da Figura Humana” de Machower, adaptado por Van Kolck (1956; 1984). A discussão teórica dos resultados baseou-se numa abordagem psicanalítica pós-freudiana para a compreensão da adolescência tanto como fase do desenvolvimento humano como dos comportamentos antissociais. Os resultados do estudo corroboraram a teoria advinda da literatura psicológica que aborda padrões comuns no período da adolescência, fase em que ocorre um complexo de fatores individuais da maturidade biológica associados ao meio social/cultural e que, por sua vez, estabelecem relações com as instâncias psicológicas ou psíquicas do sujeito junto com as características específicas de cada indivíduo. Na busca da compreensão desses padrões comuns da amostra dos adolescentes infratores utilizados no presente estudo, foram levantados dados do perfil psicossocial, cultural e demográfico; dos aspectos psicossociais e aspectos psicodinâmicos e de características de personalidade. A título de conclusão, o estudo destacou a problemática do adolescente em conflito com a lei, associada às questões sociais, de saúde mental, além do desenvolvimento psíquico, sinalizando a necessidade de ações psicoprofiláticas voltadas para população infantil, jovem, agrupamentos familiares e para a comunidade que representa seu entorno.

Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site

The Pointed (PNT) domain and an adjacent mitogen-activated protein (MAP) kinase phosphorylation site are defined by sequence conservation among a subset of ets transcription factors and are implicated in two regulatory strategies, protein interactions and posttranslational modifications, respectively. By using NMR, we have determined the structure of a 110-residue fragment of murine Ets-1 that includes the PNT domain and MAP kinase site. The Ets-1 PNT domain forms a monomeric five-helix bundle. The architecture is distinct from that of any known DNA- or protein-binding module, including the helix-loop-helix fold proposed for the PNT domain of the ets protein TEL. The MAP kinase site is in a highly flexible region of both the unphosphorylated and phosphorylated forms of the Ets-1 fragment. Phosphorylation alters neither the structure nor monomeric state of the PNT domain. These results suggest that the Ets-1 PNT domain functions in heterotypic protein interactions and support the possibility that target recognition is coupled to structuring of the MAP kinase site.

Yeast microarrays for genome wide parallel genetic and gene expression analysis

We have developed high-density DNA microarrays of yeast ORFs. These microarrays can monitor hybridization to ORFs for applications such as quantitative differential gene expression analysis and screening for sequence polymorphisms. Automated scripts retrieved sequence information from public databases to locate predicted ORFs and select appropriate primers for amplification. The primers were used to amplify yeast ORFs in 96-well plates, and the resulting products were arrayed using an automated micro arraying device. Arrays containing up to 2,479 yeast ORFs were printed on a single slide. The hybridization of fluorescently labeled samples to the array were detected and quantitated with a laser confocal scanning microscope. Applications of the microarrays are shown for genetic and gene expression analysis at the whole genome level.

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

Although transcription and pre-mRNA processing are colocalized in eukaryotic nuclei, molecules linking these processes have not previously been described. We have identified four novel rat proteins by their ability to interact with the repetitive C-terminal domain (CTD) of RNA polymerase II in a yeast two-hybrid assay. A yeast homolog of one of the rat proteins has also been shown to interact with the CTD. These CTD-binding proteins are all similar to the SR (serine/arginine-rich) family of proteins that have been shown to be involved in constitutive and regulated splicing. In addition to alternating Ser-Arg domains, these proteins each contain discrete N-terminal or C-terminal CTD-binding domains. We have identified SR-related proteins in a complex that can be immunoprecipitated from nuclear extracts with antibodies directed against RNA polymerase II. In addition, in vitro splicing is inhibited either by an antibody directed against the CTD or by wild-type but not mutant CTD peptides. Thus, these results suggest that the CTD and a set of CTD-binding proteins may act to physically and functionally link transcription and pre-mRNA processing.

U-M Softball Team, 1997

Front Row: Sara Griffin, Kellyn Tate, Jessica Lang (captain), Kelly Holmes, Jen Smith, Tracy Taylor, Jen McKittrick, Lisa Kelley.

Back Row: Cathy Davie, Traci Conrad, Stacey Judd, Jamie Gillies, Melissa Gentile, Karmen Lappo, Pam Kosanke, Tammy Mika, Lisa Beard.

Not Pictured: Mary Adams.

U-M Softball Team, 1998

Back Row: Melissa Taylor, Christine Garza, Courtney Murdock, Melissa Gentile, Rebecca Tune, Marie Barda, Kim Bugel

Middle Row: Stacey Judd, Karmen Lappo, Traci Conrad, Tammy Mika, Cathy Davie, Pam Kosanke, Jamie Gillies

Front Row: Sara Griffin, Jennifer McKittrick (captain), Lisa Kelley, Kellyn Tate (captain) Blanc LeBron (manager)

U-M Softball Team, 1999

Front Row: Pam Kosanke, Blanca LeBron (mgr.), Traci Conrad (captain), Catherine Davie, Tammy Mika (captain), Carrie Silver (mgr.).

Middle Row: Rebecca Tune, Marie Barda, Melissa Gentile, Jamie Gillies, Courtney Murdock, Kate Eiland, Karmen Lappo.

Back Row: Kristen Hunter, Stefanie Volpe, Mary Conner, Kelsey Kollen, Chrissy Garza, Melissa Taylor, Lisa Beard, Kim Bugel.

U-M Softball Team, 2000

Front Row: Karmen Lappo, Jamie Gillies, Melissa Gentile (co-captain), Pam Kosanke (co-captain),

Second Row: Kate Eiland, Marissa Young, Courtney Murdock, Melinda Moulden, Meghan Doe, Marie Barda, Mary Conner.

Third Row: Liz Elsner, Chrissy Garza, Rebecca Tune, Kelsey Kollen, Stefanie Volpe,

Top Row: Melissa Taylor, Lisa Mack, Kim Bugel.

UM Men's Swimming Team, 1979 UM Swimming

Front Row: Michael W. Darland, Thomas W. Pederson, Eric A. Peper, C. Matthew Chelich, Fernando J. Canales, Robert F. Murray, Kevin V. Williamson

2nd Row: Richard L. Carter, Paul W. Griffith, Scott D. Weir, Kenneth J. Vigiletti, Jonathan K. Menegay, Kevin A. Morgan, David L. Price, Bill Mills, James F. Derks

3rd Row: swimming coach Gus Stager, Jon Beach, Kevin Machemer, Brent Campbell, Lance Weissmann, Matt Kanzler, Tom D. Dudley, Jr., R. Scott Crowder, III., Walter H. Gage, III, diving coach Dick Kimball

Back Row: Rich D. Hitt, Jr., Jamie Gentile, John L. Spaid, Mark McMann, Mike Wilson, Michael W. Dauw, John E. Slykhouse, Eric Yamauchi, Andy Griffith, Thomas D. Ernsting, Bruce Temme

Four piano compositions [op. 7] / by Ethelbert Nevin.

Valzer gentile -- Slumber song -- Intermezzo -- Song of the brook.

Dante e l'Italia : nel VI centenario della morte del poeta, 1921.

Includes bibliographical references.

Teoria generale dello spirito come atto puro.

Mode of access: Internet.

Gentilis de febribus cu[m] receptis suis positis ad capitula propia nouissime recognitus, infinitisq[ue] erroribus castigatus ; Addito eleganti repertorio nouiter excogitato, quod omnes principales questiones mirifice complectitur.

Incluye la fen primera del libro IV del Canon de Avicena, según la versión latina de Gerardo de Cremona.

Domini Gentilis Fulginatis ... Singulare consilium contra pestilentiam ; eiusdem questio perutilis de resistentijs seu de contra operantijs.

Ruiz Fidalgo