A metric map of humans: 23,500 loci in 850 bands

High-resolution maps integrated with the enhanced location data base software (ldb+) give improved estimates of genetic parameters and reveal characteristics of cytogenetic bands. Chiasma interference is intermediate between Kosambi and Carter–Falconer levels, as in Drosophila and the mouse. The autosomal genetic map is 2832 and 4348 centimorgans in males and females, respectively. Telomeric T-bands are strikingly associated with male recombination and gene density. Position and centromeric heterochromatin have large effects, but nontelomeric R-bands are not significantly different from G-bands. Several possible reasons are discussed. These regularities validate the maps, despite their high resolution and inevitable local errors. No other approach has been demonstrated to integrate such a large number of loci, which are increasing at about 45% per year. The maps and the data and software from which they are constructed are available through the Internet (http://cedar.genetics.soton.ac.uk/public_html). Successive versions of this location data base may also be accessed on CD-ROM.

Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders.

Aberrations of the long arm of chromosome 11 are among the most common chromosome abnormalities in lymphoproliferative disorders (LPD). Translocations involving BCL1 at 11q13 are strongly associated with mantle cell lymphoma. other nonrandom aberrations, especially deletions and, less frequently, translocations, involving bands 11q21-923 have been identified by chromosome banding analysis. To date, the critical genomic segment and candidate genes involved in these deletions have not been identified. In the present study, we have analyzed tumors from 43 patients with LPD (B-cell chronic lymphocytic leukemia, n = 40; mantle cell lymphoma, n = 3) showing aberrations of bands 11q21-923 by fluorescence in situ hybridization. As probes we used Alu-PCR products from 17 yeast artificial chromosome clones spanning chromosome bands 11q14.3-923.3, including a panel of yeast artificial chromosome clones recognizing a contiguous genomic DNA fragment of approximately 9-10 Mb in bands 11q22.3-923.3. In the 41 tumors exhibiting deletions, we identified a commonly deleted segment in band 11q22.3-923.1; this region is approximately 2-3 Mb in size and contains the genes coding for ATM (ataxia telangiectasia mutated), RDX (radixin), and FDX1 (ferredoxin 1). Furthermore, two translocation break-points were localized to a 1.8-Mb genomic fragment contained within the commonly deleted segment. Thus, we have identified a single critical region of 2-3 Mb in size in which 11q14-923 aberrations in LPD cluster. This provides the basis for the identification of the gene(s) at 11q22.3-923.1 that are involved in the pathogenesis of LPD.

The Star collection of instrumental music; arranged for wind and string instruments, and for the use of small bands and orchestras.

Contains arrangements of songs, selections from operas, dances, etc.

Songs of progress and affection for the people : with the "Songs of health and temperance": being sixty two original and selected melodies arranged for two or four parts, for schools, bands of hope, popular meetings or the home circle.

Music only. "The words to these songs are printed separately."

Plate with figures around a pool, two bands of Naskhi inscription

Shamsuddin al-Hasani Abu Zayd; 1 29/64 in.x 1 ft. 1 55/64 in.x 9 59/64 in.; stone-paste painted over glaze with luster

Nitric oxide bands near 1 [mu] in shockheated air,

"Contract no. DA-30-069-ORD-3443. ARPA no. 253-62."

The first and second positive bands of N2 /

Mode of access: Internet.

Treaty between the United States of America and the western bands of Shoshonee Indians.

"Concluded at Ruby valley, in the territory of Nevada."

The bands of Orion,

Mode of access: Internet.

Treaty between the United States of America and the Chippewas of the Mississippi and the Pillager and Lake Winibigoshish bands of Chippewa Indians in Minnesota. Concluded March 11, 1863. Ratification advised with amendments, by Senate, March 13, 1863. Amendments accepted March 14, 1863. Proclaimed March 19, 1863.

"Concluded at ... Washington ... District of Columbia."

World Percussion Bash UW Percussion Ensemble UW Gamelan Ensemble UW Steel Bands May 25, 2016

Concert Program