972 resultados para Traveling exhibit


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In the present study, interleukin-6 (IL-6)-deficient mice were infected with Giardia lamblia clone GS/M-83-H7. Murine IL-6 deficiency did not affect the synthesis of parasite-specific intestinal immunoglobulin A. However, in contrast to wild-type mice, IL-6-deficient animals were not able to control the acute phase of parasite infection. Reverse transcription-PCR-based quantitation of cytokine mRNA levels in peripheral lymph node cells exhibited a short-term up-regulation of IL-4 expression in IL-6-deficient mice that seemed to be associated with failure in controlling the parasite population. This observation suggests a further elucidation of IL-4-dependent, Th2-type regulatory processes regarding their potential to influence the course of G. lamblia infection in the experimental murine host.

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Reproduced from typewritten copy.

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Disbound Original Held in Oak Street Library Facility.

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Public Health Service, Bethesda, Md.

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Mode of access: Internet.

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"Supported in part jointly by the Atomic Energy Commission and the Advanced Research Projects Agency (ARPA) under AEC Contract AT(11-1)-1018."

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"Contract No. AF33(616)-3220 Project No. 6(7-4600) Task 40572 Wright Air Development Center"