928 resultados para Tratados


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The effects of extracts from Azadirachta indica A. Juss and streptozotocin, in extreme high dilutions in dinamized systems, on hepatocyte morphometry of rats with diabetes mellitus induced by streptozotocin were evaluated. Some parameters presented significant differences among the experimental groups, but the effect of treatments to make better or worse the consequences of diabetes mellitus on liver was not detected using only the hepatocyte morphometry. The morphometric analysis evidenced that the white control group presented the highest mean values for nucleus and cytoplasm parameters, with the exception of the nuclear shape factor. However, this situation did not imply the diabetes mellitus was the cause of drastic reduction in these values, since the literature describes lower measurements for rats from the control group (non-diabetic rats).

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Planteamiento acerca de los elementos a considerar en los planes gubernamentales, respecto a las áreas ocupadas por Estados Unidos que están reincorporándose a la soberanía panameña, teniendo en vista sus efectos demográficos.

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Atherosclerosis is a multifactorial, progressive and slow disease, and hyperlipidaemia is one of the potential factors in the development of atherosclerotic cardiac diseases. The experimental dyslipidaemia carrying out advantages are the production of atheromatous lesions in a short period of time, an adequate dietetic control and environmental factors, the possibility of studies concerning reversibility of atherosclerotic lesions, and pre-clinic experiments with hypolipidaemic substances. This study aims at evaluating tyloxapol analyzing serum lipid levels. Twenty-eight healthy Wistar adults' albino male rats, weighing an average of 200 g were utilized. They were distributed into four experimental groups with seven animals each, as follows: Group I - (control); Group II - treated with tyloxapol at a dose of 500mg/kg of body weight, through intraperitoneal via each 48 hours, for two weeks; Group III - treated with tyloxapol at a dose of 500mg/ kg of body weight, through intraperitoneal via each 48 hours, for three weeks; Group IV - treated with tyloxapol at a dose of 500mg/kg of body weight, through intraperitoneal via each 48 hours, for four weeks. As lipid profile evaluation is concerned, the values of triacylglycerols and HDL have indicated that group III has significantly differed from group I and the values of total cholesterol and LDL have indicated that group I has significantly differed from group II, III and IV. It was concluded that for the studied period the surfactant tyloxapol was effective to inducing hyperlipidaemia.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Ciência e Tecnologia de Materiais - FC

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Ciências Fisiológicas - FOA

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)