Pensioners' Post, Summer 2002

IPERS is prefunded, which means that while members are working they contribute to IPERS for their own future retirements. Contributions from employees and their employers, plus investment income, must be enough to cover the costs of future benefits that IPERS promises to pay.

Pensioners' Post, Summer 2003

IPERS is prefunded, which means that while members are working they contribute to IPERS for their own future retirements. Contributions from employees and their employers, plus investment income, must be enough to cover the costs of future benefits that IPERS promises to pay.

Pensioners' Post, Summer 2004

IPERS is prefunded, which means that while members are working they contribute to IPERS for their own future retirements. Contributions from employees and their employers, plus investment income, must be enough to cover the costs of future benefits that IPERS promises to pay.

Iowa EHDI News, Summer 2009

The purpose of the newsletter is to communicate with parents and professionals about newborn hearing screening and follow up in Iowa. We will share information about: Hearing screenings Early intervention, including communication opportunities Resources available for parents and professionals “Best practices” by hospitals, Area Education Agencies (AEAs), private practice audiology offi ces or other health and education providers working with children who are deaf or hard of hearing National research Iowa EHDI program goals EHDI program progress, system development, evaluation Family stories Highlights from the EHDI Advisory Committee

Iowa EHDI News, Summer 2010

The purpose of the newsletter is to communicate with parents and professionals about newborn hearing screening and follow up in Iowa. We will share information about: Hearing screenings Early intervention, including communication opportunities Resources available for parents and professionals “Best practices” by hospitals, Area Education Agencies (AEAs), private practice audiology offi ces or other health and education providers working with children who are deaf or hard of hearing National research Iowa EHDI program goals EHDI program progress, system development, evaluation Family stories Highlights from the EHDI Advisory Committee

Iowa EHDI News, Summer 2011

The purpose of the newsletter is to communicate with parents and professionals about newborn hearing screening and follow up in Iowa. We will share information about: Hearing screenings Early intervention, including communication opportunities Resources available for parents and professionals “Best practices” by hospitals, Area Education Agencies (AEAs), private practice audiology offi ces or other health and education providers working with children who are deaf or hard of hearing National research Iowa EHDI program goals EHDI program progress, system development, evaluation Family stories Highlights from the EHDI Advisory Committee

The Latest Word, Summer 2012

Newsletter by IPERS about Iowa Public Employees’ Retirement System news for retirees.

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice.

Epoxyeicosatrienoic acids (EETs) are small molecules produced by cytochrome P450 epoxygenases. They are lipid mediators that act as autocrine or paracrine factors to regulate inflammation and vascular tone. As a result, drugs that raise EET levels are in clinical trials for the treatment of hypertension and many other diseases. However, despite their pleiotropic effects on cells, little is known about the role of these epoxyeicosanoids in cancer. Here, using genetic and pharmacological manipulation of endogenous EET levels, we demonstrate that EETs are critical for primary tumor growth and metastasis in a variety of mouse models of cancer. Remarkably, we found that EETs stimulated extensive multiorgan metastasis and escape from tumor dormancy in several tumor models. This systemic metastasis was not caused by excessive primary tumor growth but depended on endothelium-derived EETs at the site of metastasis. Administration of synthetic EETs recapitulated these results, while EET antagonists suppressed tumor growth and metastasis, demonstrating in vivo that pharmacological modulation of EETs can affect cancer growth. Furthermore, inhibitors of soluble epoxide hydrolase (sEH), the enzyme that metabolizes EETs, elevated endogenous EET levels and promoted primary tumor growth and metastasis. Thus, our data indicate a central role for EETs in tumorigenesis, offering a mechanistic link between lipid signaling and cancer and emphasizing the critical importance of considering possible effects of EET-modulating drugs on cancer.

Immunization Update, Summer 2013

Monthly newsletter for the Iowa Department of Public Health

IRENE newsletter. Volume 1, number 1 (Spring/Summer 2007)

IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.

IRENE newsletter. Volume 2, number 1 (Spring/Summer 2008). University of Iowa

IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.

IRENE newsletter. Volume 4, number 1 (Spring/Summer 2010)

IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.

IRENE newsletter. Volume 2, number 1 (Spring/Summer 2008)

IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.

IRENE newsletter. Volume 3, number 1 (Spring/Summer 2009)

IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.

IRENE newsletter. Volume 5, number 1 (Spring/Summer 2010)

IRENE’s mission is to improve the health and well-being of Iowans through collaboration in practice-based research on questions important to primary care physicians and their patients. IRENE’s purpose is to create and foster a network of research collaboration between the academic medical center and primary care physicians through out the state of Iowa with a particular focus on improving rural health.