Cuba: evaluacion y ajuste del censo de 1953 y las estadisticas de nacimientos y defunciones entre 1943 y 1958. Tabla de mortalidad por sexo, 1952-1954

Incluye Bibliografía

America Latina: analisis preliminar de la vinculacion entre algunas variables economicas y aspectos de la poblacion, 1950-1960

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Notas para una discusion acerca de la ley de poblacion en Marx

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Cuba: los componentes de la mortalidad entre 1919-1954. Utilidad de la proyeccion de la mortalidad

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El ambiente competitivo de la región Arequipa: una visión panorámica

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Deproteinized bovine bone mineral particles and osseointegration of implants without primary bone contact: An experimental study in dogs

Objectives: To evaluate the influence on osseointegration of Deproteinized bovine bone mineral (DBBM) particles used to fill defects of at least 1 mm around implants having no primary contact with bone. Material and methods: Premolars and first molars were extracted bilaterally from the mandible of six Labrador dogs. After 3 months of healing, mucoperiosteal full-thickness flaps were elevated, and one recipient site was prepared in the molar region of each hemi-mandible to place implants. These were installed with a deliberate circumferential and periapical space to the bone walls of 1.2 mm. All implants were stabilized with passive fixation plates to maintain the implants in situ and without any contact with the implant bed. The control sites were left to be filled with coagulum, while at the test sites, the residual gap was filled with DBBM. After 3 months of submerged healing, the animals were sacrificed. Ground sections were prepared and analyzed histomorphometrically. Results: Mineralized bone-to-implant contact was 4.0% and 3.9% for control and test sites, respectively. The width of the residual defects was 0.48 mm and 0.88 mm at the control and test sites, respectively. The percentage of implant surface covered by a layer of dense connective tissue of 0.12 mm of width on average was 84.9% and 88.5% at the control and test sites, respectively. Conclusion: A minor and not predictable degree of contact or distance osteogenesis was obtained on the implant surface when primary contact of the implant surface with the implant bed had deliberately been avoided. DBBM grafting of the artificial gap did not favor osseointegration. Neither did it enhance the ability to bridge the gap with newly formed bone in an artificial defect wider than 1 mm. © 2013 John Wiley & Sons A/S.

Metodologia para o planejamento da operação de sistemas hidrotérmicos em mercado elétrico competitivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Proyecto para prevenir el embarazo en jóvenes de 11-19 años en los distritos de San Gregorio Poniente, Parque Intercomunal y San Gregorio Oriente de la comuna La Granja

El proyecto tiene como metas contribuir a disminuir la incidencia de embarazos en adolescentes de 11-19 años en los distritos San Gregorio Poniente, Parque Intercomunal y San Gregorio Oriente de la comuna de la Granja. Los principales productos lo constituyen: a) 6 talleres de capacitación sobre sexualidad del adolescente a 30 personas de los programas de planificación familiar; b) formación en sexualidad y manejo de grupo de 350 promotores juveniles (150 de 11-14 años y 200 de 15-19 años en 17 grupos; c) elaboración de material educativo sobre sexualidad y anticoncepción; d) campañas educativas dirigidas a 3.483 jóvenes de 11-19 años de edad; e) formación de 16 clubes de padres; f) formación de 35 grupos juveniles que operen en organizaciones comunitarias; g) propuestas de incorporación de contenidos sobre educación sexual en la currícula de la enseñanza primaria y media.

Análise do potencial mutagênico dos esteroides anabólicos androgênicos (EAA) e da l-carnitina mediante o teste do micronúcleo em eritrócitos policromáticos

INTRODUCTION: Anabolic androgenic steroids (AAS) are frequently used by people whose aim to increase muscle mass to obtain a better performance in sports or improve physical appearance. AAS are synthetic derivatives of testosterone, able to promote muscle fibers hypertrophy, increasing intracellular protein synthesis. L-carnitine is a food supplement used to increase energetic production by means of fat acids oxidation. Although there are several works about physiological properties of these drugs, there are few studies about their mutagenic potential. OBJECTIVES: This work evaluated the clastogenicity and genotoxicity of nandrolone decanoate, testosterone decanoate and L-carnitine, in different treatments through the micronucleus test in polychromatic erythrocytes of Wistar rats. METHODS: The animals were submitted to different concentrations and associations of AAS. The positive control received cyclophosphamide 50 mg/kg by intraperitoneal injection and negative control, one ml of saline solution by gavage. The rats were sacrificed after 36 hours of latest application, having the femurs removed and the bone marrow extracted. Material was homogenized and centrifuged. Button cell was pipetted and transferred to slides, which were stained by Giemsa. 1,000 polychromatic erythrocytes were counted per animal, noting the frequency of micronuclei. RESULTS: The Kruskal-Wallis test was performed, with a significance level of 5%, which demonstrated that nandrolone decanoate - three doses of 0,2 mg/kg and 0,6 mg/kg, eight doses of 7,5 mg/kg, L-carnitine - seven doses of 0,4 ml/250 g and 1,5 ml/250 g, testosterone decanoate - 28 doses of 0,075 mg/kg, nandrolone decanoate - eight doses of 7,5 mg/kg associated to L-carnitine and 1 mL and nandrolone decanoate - eight doses of 7,5 mg/kg associated to testosterone decanoate - eight doses of 7,5 mg/kg, showed mutagenic potential. CONCLUSION: The treatments proved to be clastogenic, not being indicated like ergogenic aid.

Reformas estruturais no Brasil na década de 1990 e seu impacto sobre o emprego

O país passou por um período de grandes transformações no último quarto do século XX, os quais afetaram em grande medida a esfera social, política e econômica da sociedade. Dado o enfraquecimento do Estado de Bem Estar Social, e a ascensão do pensamento neoliberal nos anos 1970, houve a revisão do papel do Estado em todo o globo. As reformas neoliberais durante a década de 1990 tiveram um impacto significativo sobre os níveis do produto, e refletiram na redução do emprego até o fim da década, além do surgimento de novas formas de precarização do trabalho. Este trabalho tem como principal objetivo elucidar o impacto destas reformas estruturais sobre o emprego e seus desdobramentos na sociedade

Comparación de la conductancia hidráulica dentinaria, de acuerdo al tiempo de aplicación de desensibilizantes con base de oxalatos

ABSTRACT. Introduction: an in vitro model was used to measure the hydraulic conductance in human dentin discs treated with oxalic acid for 15, 30 or 60 s maintaining the occlusive effect and measuring 7 and 14 days after application. Methods: 45 dentin discs measuring 1 mm thick were obtained from human third molars which were free of caries and in no occlusion; the samples were obtained from patients aged 16 to 30 years. Discs were sorted out into three study groups (n = 15) depending on the time of application of a commercial solution of oxalate-based dentin desensitizer (DD) (BisBlock®) which contains ˂ 5% oxalic acid of 1.5-1.8 pH: in group A the agent was applied for 15 s, in group B it was applied for 30 s, and in group C for 60 s. The hydraulic conductance of each disc was calculated after acid etching, which corresponds to the maximum permeability of discs (100%) after immediate application of oxalic acid, as well as seven and fourteen days of storage in saline solution. The statistical analysis was done with ANOVA test and post-hoc Games-Howell test. Results: 35,46 ± 23.41% in Group A, 36.34 ± 15.88% in Group B and 24.99 ± 14.99% in Group C, showing that the use of DD for 15, 30 or 60 s decreased permeability in a statistically significant manner (p <0.05). Conclusions: DD was effective in reducing hydraulic conductance regardless of application time, but this reduction was temporary only, since after seven days permeability returns to values close to those of baseline.

Perfil de Aglutininas Anti-leptospira e anti-brucella e condições sanitárias de ovinos da região noroeste do Estado de São Paulo, Brasil

The sheep industry has become increasingly prominent in agribusiness, transforming the stage production of Brazil, and thus contributes more to the socio-economic development of the country. The work aimed to verify the occurrence of brucellosis and leptospirosis in sheep from northwestern São Paulo state. In addition to determining the prevalence of major Leptospira in the region and to trace the diagnosis of sheep breeding in this part of the country. All the 1222 sheep serum samples from 49 properties did not react serologically to evidentiary testing for brucellosis, compared to antigens of B. abortus and B. ovis used in the testing of 2-ME and IDGA, respectively. The Microscopic Agglutination Test (MAT) test revealed that 19.14% (232/1212) of samples were positive for one or more serovars, with titles ranging from 100 to 800. The most frequent serovar was hebdomadis in the region, with Sentot and Sherman (18.10%, 11.64% and 8.62%, respectively). By profiling the system of sheep farming in the region, we found that most herds are composed of more than one race being the main purpose is for the court. According to the scheme adopted immunoprophylactics there is a homogeneous set schedule. It adopts the use of anti-helminth, non-prescription veterinary antibiotic. There is also the presence of diarrhea and abortions and the lack of criteria for los ovinos on management, making it the need for emergency development of programs for disease control, schema immunoprophylactics adequate sanitation and hygienic measures in sheep breeding.

Systematics of the Oswaldoi Complex (Anopheles, Nyssorhynchus) in South America

Abstract Background Effective malaria control relies on accurate identification of those Anopheles mosquitoes responsible for the transmission of Plasmodium parasites. Anopheles oswaldoi s.l. has been incriminated as a malaria vector in Colombia and some localities in Brazil, but not ubiquitously throughout its Neotropical range. This evidence together with variable morphological characters and genetic differences supports that An. oswaldoi s.l. compromises a species complex. The recent fully integrated redescription of An. oswaldoi s.s. provides a solid taxonomic foundation from which to molecularly determine other members of the complex. Methods DNA sequences of the Second Internal Transcribed Spacer (ITS2 - rDNA) (n = 192) and the barcoding region of the Cytochrome Oxidase I gene (COI - mtDNA) (n = 110) were generated from 255 specimens of An. oswaldoi s.l. from 33 localities: Brazil (8 localities, including the lectotype series of An. oswaldoi), Ecuador (4), Colombia (17), Trinidad and Tobago (1), and Peru (3). COI sequences were analyzed employing the Kimura-two-parameter model (K2P), Bayesian analysis (MrBayes), Mixed Yule-Coalescent model (MYC, for delimitation of clusters) and TCS genealogies. Results Separate and combined analysis of the COI and ITS2 data sets unequivocally supported four separate species: two previously determined (An. oswaldoi s.s. and An. oswaldoi B) and two newly designated species in the Oswaldoi Complex (An. oswaldoi A and An. sp. nr. konderi). The COI intra- and inter-specific genetic distances for the four taxa were non-overlapping, averaging 0.012 (0.007 to 0.020) and 0.052 (0.038 to 0.064), respectively. The concurring four clusters delineated by MrBayes and MYC, and four independent TCS networks, strongly confirmed their separate species status. In addition, An. konderi of Sallum should be regarded as unique with respect to the above. Despite initially being included as an outgroup taxon, this species falls well within the examined taxa, suggesting a combined analysis of these taxa would be most appropriate. Conclusions: Through novel data and retrospective comparison of available COI and ITS2 DNA sequences, evidence is shown to support the separate species status of An. oswaldoi s.s., An. oswaldoi A and An. oswaldoi B, and at least two species in the closely related An. konderi complex (An. sp. nr. konderi, An. konderi of Sallum). Although An. oswaldoi s.s. has never been implicated in malaria transmission, An. oswaldoi B is a confirmed vector and the new species An. oswaldoi A and An. sp. nr. konderi are circumstantially implicated, most likely acting as secondary vectors.