Drug abuse prevention for the media.

Mode of access: Internet.

Marijuana : what it is and what it does.

Mode of access: Internet.

Drug program report : the National Training System, a year of transition, 1981-1982.

"Written for the Training Division, National Institute on Drug Abuse by the Career Development Center, HCS, Inc., ... under contract number 271-80-4807"--T.p. verso.

Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress

Hepatocellular cancer is the fifth most frequent cancer in men and the eighth in women worldwide. Established risk factors are chronic hepatitis B and C infection, chronic heavy alcohol consumption, obesity and type 2 diabetes, tobacco use, use of oral contraceptives, and aflatoxin-contaminated food. Almost 90% of all hepatocellular carcinomas develop in cirrhotic livers. In Western countries, attributable risks are highest for cirrhosis due to chronic alcohol abuse and viral hepatitis B and C infection. Among those with alcoholic cirrhosis, the annual incidence of hepatocellular cancer is 1-2%. An important mechanism implicated in alcohol-related hepatocarcinogenesis is oxidative stress from alcohol metabolism, inflammation, and increased iron storage. Ethanol-induced cytochrome P-450 2E1 produces various reactive oxygen species, leading to the formation of lipid peroxides such as 4-hydroxy-nonenal. Furthermore, alcohol impairs the antioxidant defense system, resulting in mitochondrial damage and apoptosis. Chronic alcohol exposure elicits hepatocyte hyperregeneration due to the activation of survival factors and interference with retinoid metabolism. Direct DNA damage results from acetaldehyde, which can bind to DNA, inhibit DNA repair systems, and lead to the formation of carcinogenic exocyclic DNA etheno adducts. Finally, chronic alcohol abuse interferes with methyl group transfer and may thereby alter gene expression.

Identification of maltreatment type in children with disabilities using the National Child Abuse and Neglect Data System (NCANDS)

This study was a retrospective design and used secondary data from the National Child Abuse and Neglect Data System (NCANDS), provided by the National Data Archive on Child Abuse and Neglect Family Life Development Center administered by Cornell University. The dataset contained information for the year 2005 on children from birth to 18 years of age. Child abuse and neglect for disabled children, was evaluated in-depth in the present study. Descriptive and statistical analysis was performed using the children with and without disabilities. It was found that children with disabilities have a lower rate of substantiation that likely indicates the interference of reporting due to their handicap. The results of this research demonstrate the important need to teach professionals and laypersons alike on how to recognize and substantiate abuse among disabled children.^

Women & drug abuse : you and your community can help.

"Printed 1994"--P. [12].

Recovery training and self-help : handbook for program administrators /

"Printed 1993"--T.p. verso.

Program development for community AIDS outreach /

Shipping list no.: 92-205-P.

Outreach risk reduction strategies for changing HIV-related risk behaviors among injection drug users : the National AIDS Demonstration Research (NADR) Project.

S/N 017-024-01531-8 (GPO)

Drug abuse prevention for the general population /

"Contract number 271-90-2200"--T.p. verso.

Development of a low cost portable fluorometry technology and quantification of cannabinoids in body fluids. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Audiovisual catalog - NIDA Resource Center.

Issue for 1978 was sent to depository libraries under Item no. 467-A-1.

Training of trainers : 1982 supplement.

G.P.O. sales statement incorrect in publication.

Proceedings /

Proceedings of 7th meeting, held in New York, N.Y., Dec. 4-7, 1979.

Basic management skills : resource manual /

Operated pursuant to contract no. 271-75-4018.