Abrupt vegetation change after the Late Quaternary megafaunal extinction in southeastern Australia

A substantial extinction of megafauna occurred in Australia between 50 and 45 kyr ago, a period that coincides with human colonization of Australia. Large shifts in vegetation also occurred around this time, but it is unclear whether the vegetation changes were driven by the human use of fire-and thus contributed to the extinction event-or were a consequence of the loss of megafaunal grazers. Here we reconstruct past vegetation changes in southeastern Australia using the stable carbon isotopic composition of higher plant wax n-alkanes and levels of biomass burning from the accumulation rates of the biomarker levoglucosan from a well-dated sediment core offshore from the Murray-Darling Basin. We find that from 58 to 44 kyr ago, the abundance of plants with the C-4 carbon fixation pathway was generally high-between 60 and 70%. By 43 kyr ago, the abundance of C-4 plants dropped to 30% and biomass burning increased. This transient shift lasted for about 3,000 years and came after the period of human arrival and directly followed megafauna extinction at 48.9-43.6 kyr ago. We conclude that the vegetation shift was not the cause of the megafaunal extinction in this region. Instead, our data are consistent with the hypothesis that vegetation change was the consequence of the extinction of large browsers and led to the build-up of fire-prone vegetation in the Australian landscape.

アラブ首長国連邦の対イラン経済関係と今後の展望

This paper investigates the changes in economic relations between Iran and the UAE, which historically has continued maintaining close economic intercourse with Iran in the Gulf Area, examining the prospects for change in their relationships in the future. By focusing on their trade relations and workers' remittances among the GCC and Iran, this paper discusses changes in their economic linkages. The result of the analysis shows that the economic linkages with the UAE were closer with Iran than other GCC countries during the period 2000 - 2014.

Boards of directors and bank performance in United Arab Emirates

This study presents an empirical analysis about corporate governance of financial institutions in United Arab Emirates (UAE). The purpose of this research is to analyze the influence of the structure of board of directors on the performance of these institutions. To examine the effect of control exerted by particular families on bank management, we estimated models where the dependent variable is return on assets (ROA) and return on equity (ROE), independent variables are board of directors variables, and control variables are bank management variables. Our results show that the control of corporate governance by a ruler's family within a board of directors has a positive effect on bank profitability. Our results indicate that control by a ruler's family through a bank's board of directors compensates for the inadequacy of UAE's corporate governance system.

Validation of the SenseWear armband in circuit resistance training with different loads

The use of the SenseWear™ armband (SWA), an objective monitor of physical activity, is a relatively new device used by researchers to measure energy expenditure. These monitors are practical, relatively inexpensive and easy-to-use. The aim of the present study was to assess the validity of SWAs for the measurement of energy expenditure (EE) in circuit resistance training (CRT) at three different intensities in moderately active, healthy subjects. The study subjects (17 females, 12 males) undertook CRT at 30, 50 and 70% of the 15 repetition maximum for each exercise component wearing an SWA as well as an Oxycon Mobile (OM) portable metabolic system (a gold standard method for measuring EE). The EE rose as exercise intensity increased, but was underestimated by the SWAs. For women, Bland-Altman plots showed a bias of 1.13 ± 1.48 METs and 32.1 ± 34.0 kcal in favour of the OM system, while for men values of 2.33 ± 1.82 METs and 75.8 ± 50.8 kcal were recorded.

Effects of diet and exercise on metabolic syndrome and the underlying factors = Efectos de la dieta y el ejercicio sobre el síndrome metabólico y sus factores

Introducción. El número de personas que padecen síndrome metabólico ha incrementado a nivel mundial durante las últimas dos décadas. Existen numerosos estudios que tratan de comparar prevalencias según los diferentes criterios y estimaciones del riesgo metabólico. De ellos se puede concluir que el principal hallazgo ha sido recalcar la necesidad de una definición estándar universal. A pesar de estas discrepancias no hay lugar a duda sobre el problema de salud pública que esto conlleva. Se necesitan medidas y estrategias urgentes para prevenir y controlar esta emergente epidemia global y para ello se debe prestar especial atención a los cambios en el estilo de vida, fundamentalmente dieta y ejercicio. A pesar de todo, existe a día de hoy una importante controversia sobre el tipo de ejercicio más efectivo y su combinación con la dieta para conseguir mejoras en la salud. Objetivos. Estudiar los índices de riesgo metabólico empleados en la literatura científica y las terapias basadas en dieta y ejercicio para el tratamiento de los factores del síndrome metabólico en adultos con sobrepeso. Diseño de investigación. Los datos empleados en el análisis de esta tesis son, primeramente un estudio piloto, y posteriormente parte del estudio “Programas de Nutrición y Actividad Física para el tratamiento de la obesidad” (PRONAF). El estudio PRONAF es un proyecto consistente en un estudio clínico sobre programas de nutrición y actividad física para el sobrepeso y la obesidad, desarrollado en España durante varios años de intervenciones. Fue diseñado, en parte, para tratar de comparar protocolos de entrenamiento de resistencia, cargas y combinado en igualdad de volumen e intensidad, con el objetivo de evaluar su impacto en los factores de riesgo y la prevalencia del síndrome metabólico en personas con sobrepeso y obesidad. El diseño experimental es un control aleatorio y el protocolo incluye 3 modos de ejercicio (entrenamiento de resistencia, con cargas y combinado) y restricción dietética sobre diversas variables determinantes del estado de salud. Las principales variables para la investigación que comprende esta tesis fueron: actividad física habitual, marcadores de grasa corporal, niveles de insulina, glucosa, triglicéridos, colesterol total, colesterol HDL, colesterol LDL, presión arterial y parámetros relacionados con el ejercicio. Conclusiones. A) Los índices de riesgo metabólico estudiados presentan resultados contradictorios en relación al riesgo metabólico en un individuo, dependiendo de los métodos matemáticos empleados para el cálculo y de las variables introducidas, tanto en mujeres sanas como en adultos en sobrepeso. B) El protocolo de entrenamiento combinado (de cargas y de resistencia) junto con la dieta equilibrada propuesto en este estudio fue la mejor estrategia para la mejora del riesgo de síndrome metabólico en adultos con sobrepeso. C) Los protocolos de entrenamiento supervisado de resistencia, con cargas y combinado junto con la restricción nutricional, no obtuvieron mejoras sobre el perfil lipídico, más allá de los cambios conseguidos con el protocolo de dieta y recomendaciones generales de actividad física habitual en clínica, en adultos con sobrepeso. Background. Over the past two decades, a striking increase in the number of people with the MetS worldwide has taken place. Many studies compare prevalences using different criteria and metabolic risk estimation formulas, and perhaps their main achievement is to reinforce the need for a standardized international definition. Although these discrepancies, there is no doubt it is a public health problem. There is urgent need for strategies to prevent and manage the emerging global epidemic, special consideration should be given to behavioral and lifestyle, mainly diet and exercise. However, there is still controversy about the most effective type of exercise and diet combination to achieve improvements. Objectives. To study the metabolic risk scores used in the literature and the diet and exercise therapies for the treatment of the MetS factors in overweight adults. Research design. The data used in the analysis was collected firstly in a pilot study and lately, as a part of the “Programas de Nutrición y Actividad física para el tratamiento de la obesidad” study (PRONAF). The PRONAF Study is a clinical research project in nutrition and physical activity programs for overweight and obesity, carried out in Spain (2008-2011). Was designed, in part, to attempt to match the volume and intensity of endurance, strength and combined training protocols in order to evaluate their impact on risk factors and MetS prevalence in overweight and obese people. The design and protocol included three exercise modes (endurance, strength and combined training) and diet restriction, in a randomized controlled trial concerning diverse health status variables. The main variables under investigation were habitual physical activity, markers of body fat, fasting serum levels of insulin, glucose, triglycerides, total, LDL and HDL cholesterol, blood pressure and diet and exercise parameters. Main outcomes. A) The metabolic risk scores studied presented contradictory results in relation to the metabolic risk of an individual, depending on the mathematical method used and the variables included, both in healthy women and overweight adults. B) The protocol proposed for combination of strength and endurance training combined with a balance diet was the optimal strategy for the improvement of MetS risk in overweight adults. C) The intervention program of endurance, strength or combined supervised training protocol with diet restriction did not achieved further improvements in lipid profile than a habitual clinical practice protocol including dietary advice and standard physical activity recommendations, in overweight adults.

Medición de los niveles de actividad física en personas con discapacidad física mediante acelerometría y cuestionario

Objetivo: Analizar la relación entre el nivel de actividad física registrada y el percibido en población con discapacidad física mediante acelerometría y cuestionario, así como estudiar las diferencias evaluadas con ambos instrumentos según nivel de actividad física personal y otras variables como el género o uso de la silla de ruedas. Metodología: La muestra la componen 37 sujetos con discapacidad física (28 hombres y 9 mujeres), con una edad media de 38 ±10,9 años. Se dividió a la muestra en tres grupos en función del número de horas de actividad física semanal: sedentarios (S, n = 8), practicantes habituales (PH, n = 13) y practicantes de alto rendimiento (AR, n = 16). Los sujetos llevaron un monitor metabólico de actividad física SenseWear Pro Armband (SWA) durante siete días, las 24 horas. Una vez retirado, se administró el cuestionario Physical Activity Scale for Individuals with Physical Disabilities (Escala de Actividad Física para Personas con Discapacidades Físicas) para medir la actividad física percibida, recogiéndose también datos antropo-métricos y personales. Resultados: La correlación de Pearson (n = 37) mostró relación entre el PASIPD y las variables METS promedio (r=0,52; p<0,01), gasto energético en activo (r=0,35; p<0,05) y duración de la actividad física (r=0,53; p<0,01). El PASIPD (en MET hr/día) arrojó los siguientes valores según grupo: S 8,55 ±4,35; PH 12,99 ±5,88; AR 27,41 ±19,66. Según grupos, el SWA registró, entre otras variables, los METs promedio (S 1,35 ±0,26; PH 1,46 ±0,19; AR 1,70 ±0,18) y la duración de la actividad física (S 10:33:07 ±07:47:42; PH 12:59:32 ±07:21:38; AR 22:22:26 ±07:58:58). El ANOVA mostró diferencias (p<0,05) entre grupos para el PASIPD y las citadas variables del SWA. Conclusiones: Este estudio confirma la idoneidad de utilizar de forma combinada un cuestionario y un monitor metabólico de actividad física en población con discapacidad física para la evaluación del nivel de actividad física en esta población

Conformational transitions monitored for single molecules in solution.

Phenomena that can be observed for a large number of molecules may not be understood if it is not possible to observe the events on the single-molecule level. We measured the fluorescence lifetimes of individual tetramethylrhodamine molecules, linked to an 18-mer deoxyribonucleotide sequence specific for M13 DNA, by time-resolved, single-photon counting in a confocal fluorescence microscope during Brownian motion in solution. When many molecules were observed, a biexponential fluorescence decay was observed with equal amplitudes. However, on the single-molecule level, the fraction of one of the amplitudes spanned from 0 to unity for a collection of single-molecule detections. Further analysis by fluorescence correlation spectroscopy made on many molecules revealed a process that obeys a stretched exponential relaxation law. These facts, combined with previous evidence of the quenching effect of guanosine on rhodamines, indicate that the tetramethylrhodamine molecule senses conformational transitions as it associates and dissociates to a guanosine-rich area. Thus, our results reveal conformational transitions in a single molecule in solution under conditions that are relevant for biological processes.