991 resultados para Keto-Tokoi, Petri


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This paper describes a program for the automatic generation of code for Intel's 8051 microcontroller. The code is generated from a place-transition Petri net specification. Our goal is to minimize programming time. The code generated by our program has been observed to exactly match the net model. It has also been observed that no change is needed to be made to the generated code for its compilation to the target architecture. © 2011 IFAC.

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This paper presents a tool that combines two kinds of Petri Net analyses to set the fastest routes to one vehicle in a bounded area of traffic urban. The first analysis consists of the discovery of possible routes in a state space generated from an IOPT Petri net model given the initial marking as the vehicle position. The second analysis receives the routes found in the first analysis and calculates the state equations at incidence matrix created from the High Level Petri net model to define the fastest route for each vehicle that arrive in the roads. It was considered the exchange of information between vehicle and infrastructure (V2I) to get the position and speed of all vehicles and support the analyses. With the results obtained we conclude that is possible optimizing the urban traffic flow if this tool is applied to all vehicles in a bounded urban traffic. © 2012 IEEE.

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This paper presents an application to traffic lights control in congested urban traffic, in real time, taking as input the position and route of the vehicles in the involved areas. This data is obtained from the communication between vehicles and infrastructure (V2I). Due to the great complexity of the possible combination of traffic lights and the short time to get a response, Genetic Algorithm was used to optimize this control. According to test results, the application can reduce the number of vehicles in congested areas, even with the entry of vehicles that previously were not being considered in these roads, such as parked vehicles. © 2012 IEEE.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Knowledge of the effectiveness of prostaglandins in uterine involution process led to the development of protocols with its analogues in postpartum period. However, this hormone mechanism of action is not yet fully elucidated. Thus, the objective of this study was to verify if chloprostenol administration, at early or intermediary puerperium, can induce changes on progesterone, PGFM and oestradiol plasma concentrations. 30 Murrah postpartum buffaloes were randomly divided into three groups: CONT (saline, n = 10); CLO2 (chloprostenol at days 2 and 5 postpartum, n = 10) and; CLO15 (chloprostenol at days 15 and 20 postpartum, n = 10). Blood samples were collected from jugular vein to measure progesterone, PGFM and oestradiol plasma concentrations at days 2, 7, 14, 21 and 28 postpartum. CLO2 group presented lower progesterone and PGFM plasma concentrations in relation to CONT and CLO15 groups (0.23 +/- 0.00 and 0.32 +/- 0.11, 0.19 +/- 0.00 and 0.23 +/- 0.11, 0.23 +/- 0.00 and 0.30 +/- 0.19, for groups CONT, CLO2 and CLO15, respectively; P < 0.05). There was no significant difference in oestradiol plasma concentration between experimental groups (P > 0.05). Prostaglandin synthetic analogue administration induced hormonal changes in postpartum buffaloes, which can partially explain its positive effect under reproductive function of this specie.

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This paper describes a new methodology adopted for urban traffic stream optimization. By using Petri net analysis as fitness function of a Genetic Algorithm, an entire urban road network is controlled in real time. With the advent of new technologies that have been published, particularly focusing on communications among vehicles and roads infrastructures, we consider that vehicles can provide their positions and their destinations to a central server so that it is able to calculate the best route for one of them. Our tests concentrate on comparisons between the proposed approach and other algorithms that are currently used for the same purpose, being possible to conclude that our algorithm optimizes traffic in a relevant manner.

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[ES] Se propone un algoritmo para para paralelizar la simulación de un modelo realizado mediante una red de Petri temporizada con el objeto de disminuir su tiempo de ejecución.

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Questa tesi descrive e approfondisce l'algebra di processo Multi-CCS, le fornisce una semantica basata sulle reti di Petri non limitate - a correzione e miglioramento della precedente - e una dimostrazione dettagliata della sua correttezza, ovvero della bisimilitudine tra la marcatura ottenuta dalla uova semantica e da un generico processo Multi-CCS e lo stesso processo nella semantica di default definita sugli LTS

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Questa tesi si basa su una serie di lavori precedenti, volti ad analizzare la correlazione tra i modelli AUML e le reti di Petri, per riuscire a fornire una metodologia di traduzione dai primi alle seconde. Questa traduzione permetterà di applicare tecniche di model checking alle reti così create, al fine di stabilire le proprietà necessarie al sistema per poter essere realizzato effettivamente. Verrà poi discussa un'implementazione di tale algoritmo sviluppata in tuProlog ed un primo approccio al model checking utilizzando il programma Maude. Con piccole modifiche all'algoritmo utilizzato per la conversione dei diagrammi AUML in reti di Petri, è stato possibile, inoltre, realizzare un sistema di implementazione automatica dei protocolli precedentemente analizzati, verso due piattaforme per la realizzazione di sistemi multiagente: Jason e TuCSoN. Verranno quindi presentate tre implementazioni diverse: la prima per la piattaforma Jason, che utilizza degli agenti BDI per realizzare il protocollo di interazione; la seconda per la piattaforma TuCSoN, che utilizza il modello A&A per rendersi compatibile ad un ambiente distribuito, ma che ricalca la struttura dell'implementazione precedente; la terza ancora per TuCSoN, che sfrutta gli strumenti forniti dalle reazioni ReSpecT per generare degli artefatti in grado di fornire una infrastruttura in grado di garantire la realizzazione del protocollo di interazione agli agenti partecipanti. Infine, verranno discusse le caratteristiche di queste tre differenti implementazioni su un caso di studio reale, analizzandone i punti chiave.

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BACKGROUND: The role of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) in the regulation of energy metabolism and immune system by locally reactivating glucocorticoids has been extensively studied. Experiments determining initial rates of enzyme activity revealed that 11beta-HSD1 can catalyze both the reductase and the dehydrogenase reaction in cell lysates, whereas it predominantly catalyzes the reduction of cortisone to cortisol in intact cells that also express hexose-6-phosphate dehydrogenase (H6PDH), which provides cofactor NADPH. Besides its role in glucocorticoid metabolism, there is evidence that 11beta-HSD1 is involved in the metabolism of 7-keto- and 7-hydroxy-steroids; however the impact of H6PDH on this alternative function of 11beta-HSD1 has not been assessed. METHODOLOGY: We investigated the 11beta-HSD1-dependent metabolism of the neurosteroids 7-keto-, 7alpha-hydroxy- and 7beta-hydroxy-dehydroepiandrosterone (DHEA) and 7-keto- and 7beta-hydroxy-pregnenolone, respectively, in the absence or presence of H6PDH in intact cells. 3D-structural modeling was applied to study the binding of ligands in 11beta-HSD1. PRINCIPAL FINDINGS: We demonstrated that 11beta-HSD1 functions in a reversible way and efficiently catalyzed the interconversion of these 7-keto- and 7-hydroxy-neurosteroids in intact cells. In the presence of H6PDH, 11beta-HSD1 predominantly converted 7-keto-DHEA and 7-ketopregnenolone into their corresponding 7beta-hydroxy metabolites, indicating a role for H6PDH and 11beta-HSD1 in the local generation of 7beta-hydroxy-neurosteroids. 3D-structural modeling offered an explanation for the preferred formation of 7beta-hydroxy-neurosteroids. CONCLUSIONS: Our results from experiments determining the steady state concentrations of glucocorticoids or 7-oxygenated neurosteroids suggested that the equilibrium between cortisone and cortisol and between 7-keto- and 7-hydroxy-neurosteroids is regulated by 11beta-HSD1 and greatly depends on the coexpression with H6PDH. Thus, the impact of H6PDH on 11beta-HSD1 activity has to be considered for understanding both glucocorticoid and neurosteroid action in different tissues.