Histeroscopia ambulatorial com laser diodo: uma nova modalidade para tratamento de pólipos endometriais

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Análise de fatores de dor intra-operatória na cirurgia ambulatorial no câncer de mama

Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC

Efeitos da dipirona, do meloxicam e da associação dipirona e meloxicam sobre a hemostasia em cães conscientes e sobre o controle da dor pós-operatória em cadelas submetidas à ovariosalpingohisterectomia

Pós-graduação em Cirurgia Veterinária - FCAV

Modulação genética e influência de diferentes atividades físicas na dor lombar crônica: estudo de gêmeos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Anestesia convencional e técnica de tumescência em cadelas submetidas à mastectomia. Avaliação da dor pós-operatória

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaiação da Dor e da Postura em Pacientes com Lombalgia Submetidos a Dois Protocolos de Fortalecimento Abdominal

Introduction: the lumbar spine is the main part of the body responsible for the support of the loads, where approximately half of body weight is in stable balance. This support relates to the action of abdominal muscles, of great importance in the balance of that region. The existence of abdominal muscle weakness, such won’t perform its function, may induce pathological postural attitude, that predispose the pain. Objective: to compare the effects of two abdominal strengthening protocols on pain and postural alignment in individuals with low back pain. Method: participated of the study 21 individuals of both genders, with ages between 19 and 25 years old (average 21,8±1,5) and average Body Mass Index (BMI) 21,9 (±2,48), divided randomly in isometric abdominal stimulation group (n=8), abdominal strengthening group (n=7) and control group (n=6). They realized eight sessions of strengthening, when responded Visual Analogue Scale (VAS) before and after each intervention. The control group (n=6) had no intervention. The postural data had been analyzed by photogrammetry. Results: Pain and posture data were analyzed using paired t test, with signifi cance index of 5%. Postural angles had no signifi cant differences (p>0,05) from all angles analyzed after the intervention to none of the groups. For pain values, a signifi cant decrease (p<0,05) was observed since the fi fth session in patients who were treated by the abdominal exercises protocol, and the fi rst session in patients who were treated by the isometric abdominal stimulation protocol. However, this decrease in pain was immediate, not lasting along the treatment sessions, in both protocols. Conclusion: the proposed protocols did not interfere in postural alignment. They were effective to decrease pain in a same session, once the isometric was the most effective, but they weren’t effective in preserving the improves over time.

Acupuntura no tratamento de discopatias intervertebrais em cães

The intervertebral disc disease is considered a major neurological disorder involving the spinal cord, being a disease commonly seen in dogs in clinical practice of small animals. The pathophysiology of most discopathies have not been fully elucidated, but it is known that the symptoms observed will depend on the severity of spinal cord compression and location of spinal injury, ranging from localized pain to complete paralysis. Through a detailed clinical examination and laboratory tests, we choose the most appropriate treatment for each patient, which can be conservative, through the use of anti-inflammatories, analgesics and acupuncture or surgical, through decompression techniques. Acupuncture, therapeutic method of ancient Chinese medicine, uses the stimulation of specific points on the body in order to balance the body's physiological. The action mechanism of acupuncture in discopathies has not been fully elucidated, but its analgesic effects, anti-inflammatory and restoration of sensory and motor function are known, showing results as good as surgical therapy

Utilização da acupuntura no tratamento de cães com discopatia intervertebral

The intervertebral disc diseases have a high casuistic in clinical routines veterinary among dogs. These conditions can cause pain, paresis or paralysis of limbs depending on the degree of injury. Clinical signs are not limited to the intervertebral disc, other anatomical parts are included. In conventional medicine, treatment may be surgical or clinical, by the use of corticosteroids with muscle relaxants. Acupuncture was an alternative to treating these diseases due to its anti-inflammatory and analgesic effects. Although there are few studies for the treatment of discopathies, acupuncture triggers the release of substances such as dynorphins, beta-endorphins and serotonin, among others; that act inhibiting somatic and visceral pain. Electroacupuncture is used to potentiate the effects of acupuncture. It can be performed with different frequencies according to the clinical evolution. However there are different opinions related to the greater efficacy in relation to acupuncture. The restraint and monitoring of the treated animal are important factors for its recovery. The association between acupuncture and conventional treatment (surgical or clinical) achieved better results than acupuncture alone. This proves that acupuncture can be considered an option in order to minimize the complications of surgery or assist in patient recovery

Investigação da participação de adrenoceptores α1 no efeito antinociceptivo da amitriptilina em um modelo de dor neuropática

Tricyclic antidepressants, such as amitriptyline, are inhibitors of serotonin and norepinephrine neuronal reuptake and this action has been implied in changes in pain threshold supporting its use to alleviate neuropathic pain. Although is known that 1 adrenoceptors participate in the antinociceptive effect of amitriptyline it is unclear which receptor subtype is the target for the increased synaptic levels of norepinephrine resultant from the inhibition of neuronal uptake. Paradoxically, several tricyclic antidepressants including amitriptyline also behave as antagonists of 1 adrenoceptors with different affinities for its subtypes: these drugs have 10 to 100-fold higher affinities for 1A than for 1B and 1D adrenoceptors. This work investigated the involvement of 1 adrenoceptors subtypes in the antinociceptive effect of the amitriptyline in a constriction of the sciatic nerve in rats by determining the effects of subtype selective 1 adrenoceptors antagonists. Fifteen days later, mechanical hyperalgesia was analyzed in a Randall-Selitto test. The 1A-selective antagonist RS100329 was the most potent antagonist of the contractions of the rat prostate, whereas the 1D-selective antagonist BMY 7378 (up to 100g/Kg) was unable to affect these contractions. The antagonist prazosin, BMY 7378 and 5-methyl urapidil inhibited the antinociceptive effect of the amitriptyline. However, the highly selective 1A adrenoceptor antagonist RS100329 was unable to affect the antinociception induced by amitriptyline. These results point out that 1B and/or 1D adrenoceptors, but not 1A, are involved in the antinociceptive effects of amitriptyline

Estudo do efeito de diferentes protocolos fisioterapêuticos no tratamento da osteoartrite de joelho

Pós-graduação em Saúde Coletiva - FMB

Avaliação farmacológica de candidatos a fármacos para o tratamento da anemia falciforme

A anemia falciforme (AF) é a doença hematológica hereditária crônica de maior prevalência no Brasil, causada por uma mutação pontual no gene da β-globina, levando as hemácias a adquirirem formato de foice quando em estado desoxigenado. Essa alteração estrutural causa aumento da adesão celular, hipóxia local, vaso-oclusão e alterações na coagulação. O quadro clínico dos pacientes é diversificado, predominando a dor causada pelo processo inflamatório agudo e crônico, além de complicações que podem ocasionar infarto de tecidos e órgãos, levando à morte. O único fármaco aprovado pelo FDA disponível para o tratamento da doença é a hidroxiuréia (HU), mas, devido a sua toxicidade, têm sido intensificadas as buscas por novas possibilidades terapêuticas. O fator de necrose tumoral alfa (TNF-α) é uma citocina pró-inflamatória presente em grande quantidade nos pacientes portadores da doença, e o óxido nítrico pode contribuir para vasodilatação e proteção vascular. Assim, propôs-se a síntese e avaliação farmacológica de candidatos a fármacos para o tratamento da AF, desenhados com o propósito de apresentar propriedades inibidoras do TNF-α e doadoras de óxido nítrico (NO). Foi avaliada a estabilidade química dos compostos sintetizados, em água, pH 1,2 e pH 7,4, sendo o Composto II o mais estável tanto em pH ácido como em água. Em pH básico, todos os compostos se mostraram instáveis. Os compostos III e VI apresentaram uma maior inibição da agregação plaquetária, atividade também atribuída à capacidade de doação de NO. O composto III foi o único a mostrar-se inibidor de TNF-α e IL-1β, em todas as concentrações avaliadas, e, também, mostrou-se inibidor de NO, no teste induzido por LPS. Diante de todos os ensaios realizados, o composto III é o mais promissor candidato a fármaco, entre os compostos sintetizados, para o tratamento dos sintomas da anemia falciforme.

Tratamento cirúrgico de canino incluso em mento: relato de caso

The mandibular and maxillary canines when well positioned in the arch, are important functionally and aesthetically. Although these teeth are frequently malpositioned in the dental arch, their absence of eruption are not common, occuring more frequently with the maxillary canine than the mandibular canine. The canine transmigration is a well-known pre eruptive phenomenon in which the tooth goes thru the facial midline, occurring more frequently in the mandible than in maxila. Females are more susceptible than males and the right side more than the left one. Normally the patients do not show any symptoms, and this condition is observed during radiographic exams to diagnose the late exfoliation of the deciduous canine or for any other purpose. Due to the relationship between impacted canines and pathologic lesions, infection, trauma to the adjacent teeth, pain, ectopic eruption and interference with prosthesis, it´s indicated the surgical extraction of these teeth. The goal of this article is to describe and discuss the surgical treatment of an impacted canine (43) in the chin.

Uso de hialuronidato de sódio para tratamento de deslocamento anterior de disco articular com travamento bucal

Temporomandibular joint disorders causing limitation of mouth opening and pain may be related to the restriction of slipping or forward displacement of the mandibular condyle. Temporomandibluar arthrocentesis is the lavage of the joint and is regarded as a simple method that produces good results in patients with these symptoms. This article reports a case of disc displacement and closed lock in a patient who reported limited mouth opening and pain as the main symptoms. The treatment proposed was arthrocentesis and lavage, combining a corticosteroid with a sodium hyaluronate solution. It is concluded that arthrocentesis is a simple, efficient and barely invasive method for particular types of temporomandibular joint disorders and should be considered before opting for more invasive surgical procedures.

Conduta no tratamento de gengivite ulcerativa necrosante (GUN) em serviço de urgência

Necrotizing ulcerative gingivitis is a periodontal disease which suddenly appears and presents an acute clinical course, characterized by patients' pain, discomfort and halitosis. Ulceration on papilla and marginal gingiva can be observed. For this reason, patients presenting this condition may seek dental assistance in Health Units or Graduation Institutions, being the dentist responsible for the adoption of a clinical treatment that minimizes symptomatology. The purpose of this case report is to expose and discuss aspects of clinical treatment for this disease applied to the reality of this service.

Conduta de tratamento de gengivite ulcerativa necrosante (GUN) em serviço de urgência

Necrotizing ulcerative gingivitis is a periodontal disease which suddenly appears and presents an acute clinical course, characterized by patients' pain, discomfort and halitosis. Ulceration on papilla and marginal gingiva can be observed. For this reason, patients presenting this condition may seek dental assistance in Health Units or Graduation Institutions, being the dentist responsible for the adoption of a clinical treatment that minimizes symptomatology. The purpose of this case report is to expose and discuss aspects of clinical treatment for this disease applied to the reality of this service.