Methods of computing the orbit of a comet or planet : appendix to the third volume of the translation of the Méchanique céleste /

Mode of access: Internet.

Miscellaneous reflections, occasion'd by the comet which appear'd in December 1680. Chiefly tending to explode popular superstitions. Written to a doctor of the Sorbon,

Paged continuously.

Astronomische Beobachtungen über Cometen /

Princeton's copy imperfect: [18] p. of plates missing.

Scipionis Claramontii Caesenatis De sede sublvnari cometarvm opuscula tria, in supplementum Anit-Tychonis cedentia. Sunt autem: I. Consideratio observationum indicarum cometae ultimi anni MDCXVIII à P. P. Iesuitis habitarum Goae & in tractu Malabarico. II. Consideratio ac solutio rationum pro caelesti cometarum sede, quae post Anti-Tychonem prodiêre ... III. Libellus apologeticus.

Mode of access: Internet.

Über die Natur der Cometen. Beiträge zur Geschichte und Theorie der Erkenntnis.

Mode of access: Internet.

Tratado único y singular del origen de los Indios del Perú, Méjico, Santa Fé y Chile,

Mode of access: Internet.

Definitive determination of the orbit of comet 1898 I.

Typescript.

Untersuchungen über die Grösse und Helligkeit der Kometen und ihrer Schweife.

I. Die Kometen Bis zum Jahre 1760.

Über den gefürchteten Kometen des gegenwärtigen Jahres 1832 : und über Kometen überhaupt /

Mode of access: Internet.

Essai sur les comètes en général : et particulierement sur celles qui peuvent approcher de l'orbite de la terre /

Folded diagram engraved.

Sketch of the progress of physical science. By Thomas Thomson ... Also, a course of lectures on astronomy, by Dionysius Lardner, LL.D.

"The comet of 1843": p. [92]-96.

Miscellaneous reflections occasion'd by the comet which appear'd in December 1680 : chiefly tending to explode popular superstitions /

Mode of access: Internet.

The Wide-Field Plate Database: Development and Access via Internet

ACM Computing Classification System (1998): J.2.

Protein and Drug Design Algorithms Using Improved Biophysical Modeling

This thesis focuses on the development of algorithms that will allow protein design calculations to incorporate more realistic modeling assumptions. Protein design algorithms search large sequence spaces for protein sequences that are biologically and medically useful. Better modeling could improve the chance of success in designs and expand the range of problems to which these algorithms are applied. I have developed algorithms to improve modeling of backbone flexibility (DEEPer) and of more extensive continuous flexibility in general (EPIC and LUTE). I’ve also developed algorithms to perform multistate designs, which account for effects like specificity, with provable guarantees of accuracy (COMETS), and to accommodate a wider range of energy functions in design (EPIC and LUTE).

Methane Clathrates in the Solar System

We review the reservoirs of methane clathrates that may exist in the different bodies of the Solar System. Methane was formed in the interstellar medium prior to having been embedded in the protosolar nebula gas phase. This molecule was subsequently trapped in clathrates that formed from crystalline water ice during the cooling of the disk and incorporated in this form into the building blocks of comets, icy bodies, and giant planets. Methane clathrates may play an important role in the evolution of planetary atmospheres. On Earth, the production of methane in clathrates is essentially biological, and these compounds are mostly found in permafrost regions or in the sediments of continental shelves. On Mars, methane would more likely derive from hydrothermal reactions with olivine-rich material. If they do exist, martian methane clathrates would be stable only at depth in the cryosphere and sporadically release some methane into the atmosphere via mechanisms that remain to be determined. In the case of Titan, most of its methane probably originates from the protosolar nebula, where it would have been trapped in the clathrates agglomerated by the satellite's building blocks. Methane clathrates are still believed to play an important role in the present state of Titan. Their presence is invoked in the satellite's subsurface as a means of replenishing its atmosphere with methane via outgassing episodes. The internal oceans of Enceladus and Europa also provide appropriate thermodynamic conditions that allow formation of methane clathrates. In turn, these clathrates might influence the composition of these liquid reservoirs. Finally, comets and Kuiper Belt Objects might have formed from the agglomeration of clathrates and pure ices in the nebula. The methane observed in comets would then result from the destabilization of clathrate layers in the nuclei concurrent with their approach to perihelion. Thermodynamic equilibrium calculations show that methane-rich clathrate layers may exist on Pluto as well. Key Words: Methane clathrate-Protosolar nebula-Terrestrial planets-Outer Solar System.