935 resultados para Carus, Marcus Aurelius, Roman Emperor, d. 283.


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Appendix (p. 65-78) includes four shourt continuations of the Gesta in Lombardia.

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Excerpts from documents in Latin in "sechste Beilage": p. [241]-244.

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t. 10. Oeuvres critiques I: Mes haines. Marbres et plâtres. Deux ©finitions du roman. Livres d'aujourd'hui et de demain. Causeries dramatiques. Le roman expérimental.--t. 11. Oeuvres critiques II: Les romanciers naturalistes. Le naturalisme au théâtre. Nos auteurs dramatiques.--t. 12. Oeuvres critiques III: Revue dramatique. Documents littéraires. Mélanges critiques. Salons etétudes de critique d'art.--t. 13. Chroniques et polémiques l: Confidences d'une curieuse. Chroniques. Le République en marche.--t. 15. Théâtre et poèmes: Pièces dramatiques. Pièces lyriques. Préfaces. Poèmes.

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Nature of jurisprudence.--Laws of nature and of man.--Law of partnership.--Employers liability.--Theory of persecution.--Oath of allegiance.--English law as a branch of politics.--Science of case-law.--Casuistry of common sense.--Ethics and morals.-Marcus Aurelius and the stoic philosophy.--Spencer's Data of ethics.--Index.

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The molecular mechanisms behind the entry of the primordial follicle into the growing follicle pool remain poorly understood. To investigate this process further, a microarray-based comparison was undertaken between 2-day postpartum mouse ovaries consisting of primordial follicles/naked oocytes only and those with both primordial follicles and newly activated follicles (7-day postpartum). Gene candidates identified included the chemoattractive cytokine stromal derived factor-1 (SDF1) and its receptor CXCR4. SDF1 and CXCR4 have been implicated in a variety of physiological processes including the migration of embryonic germ cells to the gonads. SDF1-alpha expression increased with the developmental stage of the follicle. Embryonic expression was found to be dichotomous post-genii cell migration, with low expression in the female. Immunohistochemical studies nonetheless indicate that the autocrine pattern of expression ligand and receptor begins during embryonic life. Addition of recombinant SDF1-alpha to neonatal mouse ovaries in vitro resulted in significantly higher follicle densities than for control ovaries. TUNEL analysis indicated no detectable difference in populations of apoptotic cells of treated or control ovaries. Treated ovaries also contained a significantly lower percentage of activated follicles as determined by measurement of oocyte diameter and morphological analysis. Treatment of cultured ovaries with an inhibitor of SDF1-alpha, AMD3100, ablated the effect of SDF1-alpha. By retaining follicles in an unactivated state, SDF1/CXCR4 signaling may play an important role in maintaining the size and longevity of the primordial follicle pool. (c) 2006 Elsevier Inc. All rights reserved.

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The application of an antiserum to ultraviolet radiation (UVR)-damaged DNA is presented. A novel experimental system was employed to ascertain the limits of detection for this antiserum. Using a DNA standard containing a known amount of dimer, the limits of detection were found to be 0.9 fmol of dimer. This was compared to a limit of 20-50 fmol dimer using gas chromatography-mass spectrometry (GC-MS). Induction of thymine dimers in DNA following UVR exposure, as assessed using this antiserum in an enzyme-linked immunosorbent assay (ELISA), was compared with GC-MS measurements. The ELISA method successfully demonstrated the induction of lesions in DNA irradiated either with UVC or UVB, although despite high sensitivity, no discernible binding was seen to UVA-irradiated DNA. The antiserum was also shown to be applicable to immunocytochemistry, localising damage in the nuclei of UVR exposed keratinocytes in culture. The ability of the antiserum to detect DNA damage in skin biopsies of individuals exposed to sub-erythemal doses of UVR was also demonstrated. Moreover, the subsequent removal of this damage, as evidenced by a reduction in antiserum staining, was noted in sections of biopsies taken in the hours following irradiation. © 2003 Elsevier B.V. All rights reserved.