Avaliação do potencial mutagênico do biodiesel e de misturas de biodiesel/diesel, por meio do teste do micronúcleo em sangue periférico e de histologia de brânquias de Oreochromis niloticus

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O grupo cervejeiro nacional petrópolis na evolução do capitalismo brasileiro: concorrência e expansão territorial

The processes resulting from globalization are backdrop for the work. On the other hand the Regulation Theory is theoretical north that drives research directions. Considering these two basis, we studied the formation of economic groups as a consequence of the processes of concentration and centralization of capital, giving more emphasis on their national character. We see how they went through the restructuring process in the transition from Fordist accumulation regime to a flexible system of accumulation. We 'll discuss the brewery industry and how major industry groups are currently creating a sector overview, ranging from the productive process to the forms of competition among large companies. Specifically we will see the Petrópolis Group this framework and how the company relates to the territory, and what answers we have of this relationship in terms of local development in the territories where the group entered, and territorial changes which have occurred there

Síntese e estudo da diapocinina como um inibidor da NADPH Oxidase em neutrófilos e células mononucleares de sangue periférico

Apocynin, a methoxy-catechol originally extracted from the root of Picrorhiza kurroa, has been used as an inhibitor of the NADPH oxidase complex in phagocytic and nonphagocytic cells. Its mechanism of inhibition is linked to their prior activation through the action of peroxidases leading to oxidation of the dimeric product, diapocynin. In this study, dipocinina was synthesized and investigated its effect as an inhibitor of activation NADPH oxidase in neutrophils (PMN) and peripheral blood mononuclear cells (PBMC). The synthesis of diapocinina was performed by oxidation of apocinina by potassium persulphate in the midst of water for 5 minutes at room temperature. The precipitate was filtered and washed with water and methanol. Diapocinina was characterized by mass spectrometry. PMN and PBMC were obtained from peripheral blood of healthy donors and purified for gelatin sedimentation, or centrifugation with Histopaque ®, the red cells were lysed with ice water or ammonium chloride. Diapocinina or apocinina were incubated with opsonized zymosan, activation of PMNs and release of superoxide anion, these monitored by chemiluminescent assay dependent lucigenina. We found that diapocinina inhibitor was no better than the apocinina in PMN. However, diapocinina was more efficient than apocinina as an inhibitor of NADPH oxidase in PBMC. In conclusion, whereas PBMC are relatively poor compared with peroxidases PMN, our results are consistent with the need for oxidation apocinina for its effect as an inhibitor of NADPH oxidase

O consumo como ponto de partida para a compreensão do capitalismo: a contribuição de Veblen

Esse trabalho buscou contribuir teoricamente para o tema, com uma pesquisa bibliográfica sobre a Economia Institucional e a teoria de Veblen sobre consumo e racionalidade. Nesse trabalho foram identificados os principais conceitos do Institucionalismo, como divergem da Economia Neoclássica e a questão do consumo conspícuo abordado por Veblen

Efeito das baixas concentrações de agentes antineoplásicos sobre linfócitos humanos de sangue periférico

Our previous studies have shown that low concentrations (noncytotoxics) of antineoplastic agents modulate positively the dendritic cells, favoring their in vitro maturation and improving their antigen presenting function. The effects on colorectal cancer cells (HCT-116) were also investigated and we have observed an increased immunogenicity and susceptibility to cytotoxic T cells. Thereby, this study aimed to investigate the effect of 5-fluorouracil (5-FU) an azacitidine (AZA), in minimum effective and noncytotoxic concentrations on lymphocytes of healthy donors. In this study we have analyzed the cytotoxic effect of drugs at these concentrations as well as the proliferative ability of lymphocytes. In vitro production of IL-10 and IFN-γ has been also evaluated. We have observed that low concentrations of those chemotherapeutic agents are not cytotoxic for lymphocytes. However, the minimum effective concentrations (5-FU: 0,410±0,088 e AZA: 0,757±0,233; p<0, 05) have reduced the cell number. Proliferative activity of allogeneic lymphocytes in a mixed reaction (MLR) was not affected by the treatment. The cytokine production was not affected by the treatments, either. In conclusion, low concentrations of 5-FU and AZA has no deleterious effects on human peripheral blood lymphocytes and seems to be safe for combinatory administration with DC vaccines

Células T reguladoras em sangue periférico de cães portadores de mastocitoma cutâneo

Pós-graduação em Medicina Veterinária - FCAV

Economia Solidária e SENAES: de alternativa ao desemprego à superação do capitalismo?

A monografia procura analisar a essência da Economia Solidária no Brasil, para verificar se essa consiste apenas em mais um modo de adaptação à realidade econômica, frente ao desemprego e à pobreza, ou se possui uma profundidade maior, constituindo uma reação ao capitalismo, o que leva alguns autores a chamarem a ES de modo de produção. Para tanto, primeiramente foi realizado um levantamento de dados que expressam as características e dimensões dessa atividade no país. A seguir foram expostos os argumentos do principal autor e defensor do tema, Paul Singer, e colocadas críticas de autores marxistas. Por fim, foi feita uma análise das pretensões e resultados das políticas públicas implementadas pela SENAES, para averiguar se, na prática, essas seriam, em algum grau, facilitadoras da superação do capitalismo, ou se somente se limitam à parte da população excluída do mercado de trabalho

Capitalismo, trabalho e formação profissional: dilemas do trabalho cotidiano dos assistentes sociais em Ribeirão Preto - SP

Pós-graduação em Serviço Social - FCHS

Desenvolvimento da Suécia durante os Anos dourados do Capitalismo: fatores históricos, ascensão do Welfare State, influências de Gunnar Myrdal e o modelo Rehn-Meidner

A Suécia está entre os países desenvolvidos que mais obtiveram êxito na construção do seu Estado de Bem-Estar Social (Welfare State). Esta instituição amadureceu durante os Anos Dourados do Capitalismo (1945 - 1975). O sucesso na sua construção pode estar ligado a uma série de fatores, como: o contexto internacional de Bretton Woods; as raízes históricas do país, com suas especificidades institucionais, econômicas e sociais; a atuação do Partido Social Democrata sueco, que contou com a participação de Gunnar Myrdal, um grande pensador econômico e um dos maiores teóricos referentes ao Welfare State; o Modelo Rehn-Meidner, que foi elaborado na década de 1950 e visou crescimento econômico, pleno emprego, controle inflacionário e equalização da renda simultaneamente através de políticas macroeconômicas contracionistas, Políticas Ativas no Mercado de Trabalho e Política de Salário Solidário. Dado tudo isto, o objetivo desta pesquisa é entender o processo de desenvolvimento do país e do seu Welfare State, analisando as medidas adotadas no período de 1950 a 1975, com particular interesse em identificar as possíveis influências que o Modelo Rehn-Meidner e o pensamento econômico e político de Gunnar Myrdal tiveram na escolha das políticas que contribuíram para o desenvolvimento do país. Além disso, será analisado o ambiente internacional da época, bem como a História da Suécia, com a finalidade de identificar se e como outros fatores contribuíram para o desenvolvimento socioeconômico da Suécia e do seu Estado de Bem-Estar Social

A problematização da docência universitária no contexto do capitalismo universitário

The university environment is in metamorphosis, in a possibility of its recreation in the presence of a knowledge revolution at full XXI century. Its structure, based at a science model, presents itself undermined by not breaking the stagnation in a world that inaugurates boundaries of uncertainty for all humanity participants. From that perception, this work intend to understand how the globalization has been reduced the workforce of the university teacher. Moreover, how the hegemonic groups, derived from insertion of capitalism and globalization, root themselves in the academic environment – before considered a space of autonomy – is transforming the teaching profession through mechanisms of alienation and doctrinairism that disseminate the heteronomy as alternative for maintenance of dogmas and, therefore, certainties.

As concepções urbanísticas que impulsionaram o desenvolvimento do capitalismo e a reprodução da força de trabalho em São Paulo: sanear e excluir

This article aims to rank the main concepts in vogue in the city of São Paulo who contributed to the formulation of a shared urban oriented capitalist development and reproduction of the workforce. This way, it will discuss the main issues raised in the period, which is between the first decades of the XX Century to the end of the 1950s, trying to foresee how they worked as engineers and architects to incorporate the urbanistic proposals from Europe and the United States. And then, we will present, on the first four sections of this article, points of view that effectively impacted the paulista urban thought of the first half of the XX century: Sanitarism, pendular conception between the Mesologic Theory and the Microbian Theory; the Historicist formulation of Camillo Sitte; Howard´s garden-town and The French Experience. Our analyses were formulated having as a reference the broad systematization of bibliography and documents performed at the Arquivo Histórico Municipal (Intermediário) de Araraquara (Historical Municipal Archive from Araraquara), consultations at the the books of the library of the biblioteca da Faculdade de Arquitetura e Urbanismo da USP (USP Architecture and Urbanism College) and at the Faculdade de Ciências e Letras da UNESP, Araraquara-SP( College of Sciences and Languages from UNESP, campus Araraquara). The analisys of the performed research show that one urbanistic torrent at São Paulo State with clear influences from the conceptions that led the urbanistic debates in the first half of the XX Century. Although these conceptions compose a painting of urban transformations at São Paulo city and noticeably in some inland cities, previously to the solidification of a whole proposition for the city that was later called of Directive Plan.

Capitalismo cognitivo e a dinâmica da pequena produção agrícola alternativa no contexto local de araraquara o caso do sai sistema agroindustrial integrado do SEBRAE/SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Educação e modos de subjetivação no capitalismo contemporâneo: reflexões a partir de Zygmunt Bauman

The article aims to give a brief reflection about education in the context of consumer society from the contemporary society analyzes performed by polish sociologist Zygmunt Bauman. It’s highlighted the relationship between the educational institution and the discourse of the market and consumption that building practices that feedback into the practices and values defended by contemporary capitalism. Also it is indicated the effects produced by this relationship on the question of teaching and learning and teacher training. Finally, the article analyzes the dilemmas of the current school in the face of the weakening of human relations and their role in addressing of the problems identified.

Votán-Zapata contra a Besta-fera: escritos do EZLN contra o capitalismo no México

Pós-graduação em Ciências Sociais - FFC