Indications for treatment in adults with tricuspid valve dysfunction due to a congential cardiac anomaly

The tricuspid valve is frequently affected in adults with congenital heart disease (CHD). Disease of this valve can occur primarily or develop secondary to changes in the right ventricle caused by other defects. Quantitative echocardiographic assessment of tricuspid regurgitation is essential to assess its cause and prognosis. Treatment options vary depending on the underlying defect and right ventricular function. Surgical management of tricuspid valve disease is complex and evolving.

Composition of basalts from the north part of the Bougault anomaly, Mid-Atlantic Ridge 15°N

A quantitative model of development of magmatic and ore-magmatic systems under crests of mid-ocean ridges is constructed. Correct physical models of melting zone formation in approximation to active spreading, non-stationary dynamics of magma intrusion from a center of generation, filling of magma chambers of various shapes, feeding of fissure-type volcanoes, and retrograde boiling of melts during solidification of intrusive bodies beneath axial zones of spreading in crests of ridges are proposed. Physicochemical and mathematical theories of disintegration of multi-component solutions, growth of liquational drops of ore melts, and sublimation of components from magmatic gases are elaborated. Methods for constructing physically correct models of heat and mass transfer in heterophase media are devised. Modeling of development of magmatic and ore-magmatic systems on the basis of the Usov-Kuznetsov facies method and the Pospelov system approach are advanced. For quantitative models numerical circuits are developed and numerical experiments are carried out.

(Table T2) Remanent anomaly and Koenigsberger ratio of ODP holes

Magnetic field strength and magnetic susceptibility were logged with the geological high-resolution magnetic tool (GHMT) at three of the holes drilled during Ocean Drilling Program Leg 178 to the west of the Antarctic Peninsula. Polarity stratigraphies derived from the GHMT logs bear close resemblance to the polarities determined from core paleomagnetism at two of the holes and were used for magnetostratigraphic dating, especially in intervals where no core was recovered. Polarity is determined in the following way. First, the susceptibility log is used to determine the induced magnetization of the sediment. Then the background field, the field of the metal drill pipe, and the field anomaly of the sediment's induced magnetization are removed from the measured total field to leave the downhole anomaly of the sediment's remanent magnetization. The sign (positive or negative) of this anomaly gave a good polarity stratigraphy for Holes 1095B and 1096C, which are located in sediment drifts. A further step, correlation analysis, is based on the fact that in an interval of normal polarity sediment the remanent anomaly will correlate with the induced anomaly, whereas in reversed polarity sediment they will anticorrelate. The magnetite-rich, fine-grained sediments found in the two holes drilled into the sediment drift have a ratio of remanent to induced magnetization (the Koenigsberger ratio) of ~1. In contrast, the coarser-grained diamict sediments on the shelf have a Koenigsberger ratio of ~0.2, and extracting the remanent part of the downhole anomaly is much more difficult. By the comparison of core and log results, we can assess the viability of the GHMT polarities in detail, what proportion of the overprint in the cores is imparted by the coring process, and whether any paleointensity information is extractable from the GHMT logs.

Results of calculated surface air temperature anomaly of COSMOS Pliocene experiment 2 in NetCDF format

In this manuscript we describe the experimental procedure employed at the Alfred Wegener Institute in Germany in the preparation of the simulations for the Pliocene Model Intercomparison Project (PlioMIP). We present a description of the utilized Community Earth System Models (COSMOS, version: COSMOS-landveg r2413, 2009) and document the procedures that we applied to transfer the Pliocene Research, Interpretation and Synoptic Mapping (PRISM) Project mid-Pliocene reconstruction into model forcing fields. The model setup and spin-up procedure are described for both the paleo- and preindustrial (PI) time slices of PlioMIP experiments 1 and 2, and general results that depict the performance of our model setup for mid-Pliocene conditions are presented. The mid-Pliocene, as simulated with our COSMOS setup and PRISM boundary conditions, is both warmer and wetter in the global mean than the PI. The globally averaged annual mean surface air temperature in the mid-Pliocene standalone atmosphere (fully coupled atmosphere-ocean) simulation is 17.35 °C (17.82 °C), which implies a warming of 2.23 °C (3.40 °C) relative to the respective PI control simulation.

Subsurface oxygen maximum anomaly found at depth in Muchalat Inlet

Senior thesis written for Oceanography 445

Axial Anomaly for Eguchi-Hanson Metrics with Nonzero Total Mass

We compute the Dirac indexes for. the two spin structures kappa(0) and kappa(1) for Eguchi-Hanson metrics with nonzero total mass. It shows that the Dirac indexes do not vanish in general, and axial anomaly exists. When the metric has zero total mass, the Dirac index vanishes for the spin structure no, and no axial anomaly exists in this case.

Increased DNA Methylation at the AXIN1 Gene in a Monozygotic Twin from a Pair Discordant for a Caudal Duplication Anomaly

The AXIN1 gene has been implicated in caudal duplication anomalies. Its coding region was sequenced in both members of a monozygotic ( MZ) twin pair discordant for a caudal duplication anomaly, but no mutation was found. Using bisulfite sequencing, we examined methylation at the promoter region of the AXIN1 gene in these twins and in twin and age-matched singleton controls. Methylation of the promoter region in peripheral blood mononucleated cells was variable among individuals, including MZ pairs. In the MZ pair discordant for the caudal duplication, this region of the affected twin was significantly more methylated than that of the unaffected twin (), which was significantly more P < .0001 methylated than those of the controls (). We have confirmed that this CpG island does function as a promoter P = .02 in vitro and that its activity is inversely proportional to the extent of methylation. This finding raises the possibility that hypermethylation of the AXIN1 promoter, by mechanisms as yet undetermined, is associated with the malformation. This case may be paradigmatic for some cases of MZ discordance.

A total electron content space weather study of the Nighttime Weddell Sea Anomaly of 1996/97 southern summer with TOPEX/Poseidon radar altimetry

This paper reports on a total electron content space weather study of the nighttime Weddell Sea Anomaly, overlooked by previously published TOPEX/Poseidon climate studies, and of the nighttime ionosphere during the 1996/1997 southern summer. To ascertain the morphology of spatial TEC distribution over the oceans in terms of hourly, geomagnetic, longitudinal and summer-winter variations, the TOPEX TEC, magnetic, and published neutral wind velocity data are utilized. To understand the underlying physical processes, the TEC results are combined with inclination and declination data plus global magnetic field-line maps. To investigate spatial and temporal TEC variations, geographic/magnetic latitudes and local times are computed. As results show, the nighttime Weddell Sea Anomaly is a large (∼1,600(°)2; ∼22 million km2 estimated for a steady ionosphere) space weather feature. Extending between 200°E and 300°E (geographic), it is an ionization enhancement peaking at 50°S–60°S/250°E–270°E and continuing beyond 66°S. It develops where the spacing between the magnetic field lines is wide/medium, easterly declination is large-medium (20°–50°), and inclination is optimum (∼55°S). Its development and hourly variations are closely correlated with wind speed variations. There is a noticeable (∼43%) reduction in its average area during the high magnetic activity period investigated. Southern summer nighttime TECs follow closely the variations of declination and field-line configuration and therefore introduce a longitudinal division of four (Indian, western/eastern Pacific, Atlantic). Northern winter nighttime TECs measured over a limited area are rather uniform longitudinally because of the small declination variation. TOPEX maps depict the expected strong asymmetry in TEC distribution about the magnetic dip equator.

The knowledge transfer anomaly

Knowledge transfer between units within MNC’s and between independent organisations involved in international business is an important element of performance. Researchers have shown that generally cultural differences place difficulties in the way of both information and knowledge transfer across national borders, both within MNC’s and across organisations. This study examines the knowledge transfer process between different cultural groups in a particular setting and concludes that in this situation cultural differences do not hinder knowledge transfer. Explanations are provided for this anomaly and implications for international business managers are drawn.

Handling the Subclassing Anomaly with Object Teams

Java software or libraries can evolve via subclassing. Unfortunately, subclassing may not properly support code adaptation when there are dependencies between classes. More precisely, subclassing in collections of related classes may require reimplementation of otherwise valid classes. This problem is defined as the subclassing anomaly, which is an issue when software evolution or code reuse is a goal of the programmer who is using existing classes. Object Teams offers an implicit fix to this problem and is largely compatible with the existing JVMs. In this paper, we evaluate how well Object Teams succeeds in providing a solution for a complex, real world project. Our results indicate that while Object Teams is a suitable solution for simple examples, it does not meet the requirements for large scale projects. The reasons why Object Teams fails in certain usages may prove useful to those who create linguistic modifications in languages or those who seek new methods for code adaptation.

The Subclassing Anomaly in Compiler Evolution

Subclassing in collections of related classes may require re-implementation of otherwise valid classes just because they utilize outdated parent classes, a phenomenon that is referred to as the subclassing anomaly. The subclassing anomaly is a serious problem since it can void the benefits of code reuse altogether. This paper offers an analysis of the subclassing anomaly in an evolving object-oriented compiler. The paper also outlines a solution for the subclassing anomaly that is based on alternative code reuse mechanism, named class overriding.

Classification Trees as a Technique for Creating Anomaly-Based Intrusion Detection Systems

Intrusion detection is a critical component of security information systems. The intrusion detection process attempts to detect malicious attacks by examining various data collected during processes on the protected system. This paper examines the anomaly-based intrusion detection based on sequences of system calls. The point is to construct a model that describes normal or acceptable system activity using the classification trees approach. The created database is utilized as a basis for distinguishing the intrusive activity from the legal one using string metric algorithms. The major results of the implemented simulation experiments are presented and discussed as well.