Comparison of the effects of cetylpyridinium chloride with an essential oil mouth rinse on dental plaque and gingivitis - a six-month randomized controlled clinical trial

OBJECTIVE: To compare the effects of an experimental mouth rinse containing 0.07% cetylpyridinium chloride (CPC) (Crest Pro-Health) with those provided by a commercially available mouth rinse containing essential oils (EOs) (Listerine) on dental plaque accumulation and prevention of gingivitis in an unsupervised 6-month randomized clinical trial. MATERIAL AND METHODS: This double-blind, 6-month, parallel group, positively controlled study involved 151 subjects balanced and randomly assigned to either positive control (EO) or experimental (CPC) mouth rinse treatment groups. At baseline, subjects received a dental prophylaxis procedure and began unsupervised rinsing twice a day with 20 ml of their assigned mouthwash for 30 s after brushing their teeth for 1 min. Subjects were assessed for gingivitis and gingival bleeding by the Gingival index (GI) of Löe ; Silness (1963) and plaque by the Silness ; Löe (1964) Plaque index at baseline and after 3 and 6 months of rinsing. At 3 and 6 months, oral soft tissue health was assessed. Microbiological samples were also taken for community profiling by the DNA checkerboard method. RESULTS: Results show that after 3 and 6 months of rinsing, there were no significant differences (p=0.05) between the experimental (CPC) and the positive control mouth rinse treatment groups for overall gingivitis status, gingival bleeding, and plaque accumulation. At 6 months, the covariant (baseline) adjusted mean GI and bleeding sites percentages for the CPC and the EO rinses were 0.52 and 0.53 and 8.7 and 9.3, respectively. Both mouth rinses were well tolerated by the subjects. Microbiological community profiles were similar for the two treatment groups. Statistically, a significant greater reduction in bleeding sites was observed for the CPC rinse versus the EO rinse. CONCLUSION: The essential findings of this study indicated that there was no statistically significant difference in the anti-plaque and anti-gingivitis benefits between the experimental CPC mouth rinse and the positive control EO mouth rinse over a 6-month period.

Jesaja 53 : das Prophetenwort vom Sühnleiden des Gottesknechtes mit besonderer Berücksichtigung der jüdischen Literatur

erörtert von Gustaf H. Dalman

Jesaja 53, das Prophetenwort vom Sühnleiden des Heilsmittlers, mit bes. Berücksichtigung d. synagogalen Litteratur

erörtert von Gustaf H. Dalman

Ms. hebr. oct. 53 - Sefer Beʼer Yitsḥaḳ

Vorbesitzer: Lyon Benedek Gaudechaux; Michel Godchaux; Abraham Merzbacher

Ms. Barth. 53 - Casus longi super V libros

Vorbesitzer: Bartholomaeusstift Frankfurt am Main

Stadtbezirk 29: Urwahlbezirk 53: In der Vorversammlung wurden gewählt ...

Welsch (Projektbearbeiter): Bekanntgabe der in der Vorversammlung gewählten Kandidaten des 53. Berliner Urwahlbezirks

Versuch einer freien Übersetzung des 5. und 53. Kapitel des Jesaias

Mo. L. Fochs

Ms. germ. qu. 53 - Straßburger Chronik

Vorbesitzer: Philipp III. von Kronberg; Anastasia von Westerburg; Johann Maximilian zum Jungen

Ms. Praed. 53 - Sermones discipuli de tempore (Pars hiemalis)

Vorbesitzer: Petrus Lupolt; Dominikanerkloster Frankfurt am Main

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 658 - Mitteilungen über das im Bankhaus Muhl eingelagerte Vermögen

u.a.: Streitigkeiten über die geplante Vermögensaufteilung; Mutter-Sohn-Konflikt;