188 resultados para 3495


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Sign.: []1, *2, []2, *2, []2, A-B4, C1

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En este trabajo se introducen, en el contexto del Método de Elementos Finitos, dos alternativas posibles en relación con el concepto de acción repartida equivalente. La primera consiste en emplear pocos elementos, elevando el orden de dicha acción, mientras que la segunda se basa en emplear un mayor número de elementos dejando la acción en el orden más bajo posible. Se ilustran ambas situaciones mediante aplicaciones a los modelos de vigas de Timoshenko y Bernoulli-Euler, empleando estas acciones con diferentes órdenes, las cuales aproximan a la acción original, mediante polinomios ortogonales de Legendre en cada elemento. Como conclusión destacable, se indica que cuando se considera el menor número posible de elementos, es decir uno, para los casos de carga poco regular, ha bastado con utilizar acciones repartidas equivalentes de orden ligeramente superior al mínimo (orden cuatro), para obtener una excelente aproximación en los desplazamientos, giros y esfuerzos en el interior de los elementos.

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Chromosome bi-orientation at the metaphase spindle is essential for precise segregation of the genetic material. The process is error-prone, and error-correction mechanisms exist to switch misaligned chromosomes to the correct, bi-oriented configuration. Here, we analyze several possible dynamical scenarios to explore how cells might achieve correct bi-orientation in an efficient and robust manner. We first illustrate that tension-mediated feedback between the sister kinetochores can give rise to a bistable switch, which allows robust distinction between a loose attachment with low tension and a strong attachment with high tension. However, this mechanism has difficulties in explaining how bi-orientation is initiated starting from unattached kinetochores. We propose four possible mechanisms to overcome this problem (exploiting molecular noise; allowing an efficient attachment of kinetochores already in the absence of tension; a trial-and-error oscillation; and a stochastic bistable switch), and assess their impact on the bi-orientation process. Based on our results and supported by experimental data, we put forward a trial-and-error oscillation and a stochastic bistable switch as two elegant mechanisms with the potential to promote bi-orientation both efficiently and robustly.

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Tagged phosphorus was used to measure principal indices of mineral phosphorus variations in the euphotic zone of the East Pacific, i.e. total rate of uptake of phosphate phosphorus by microplankton (A_t), fraction consumed by phytoplankton (A_p/A_t), and turnover time (T). A_t reached its greatest values (150-280 ng/l/hour) in the upwelling zone of the Peru traverse, where development of phytoplankton was induced by upwelling. In other areas of this traverse values were 40-80 ng/l/hour in surface layers. In less productive waters on two other profiles (off Central America and California), values were lower, between 20 and 40 ng/l. On the vertical profile maxima of A_t were found at the upper boundary of the thermocline. Turnover time of PO4 phosphorus (T) in zones of phytoplankton abundance was very short, between 1.5 and 4 days. At most other stations it was 10-40 days, increasing to 100-200 days or longer at the lower boundary of the euphotic zone. In areas of phytoplankton abundance it accounted for 60-80% of total uptake of PO4 phosphorus. But in zones of elevated bacterial abundance, A_p/A_t fell to 20-40%. Data indicating lack of correlation between PO4 phosphorus and productivity are presented. It is emphasized that the above measures of PO4 phosphorus dynamics can be used for obtaining measures of functional condition and successional phase of marine plankton communities.

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Indices.