Dynamics of mobile element activity in chalcone synthase loci in the common morning glory (Ipomoea purpurea)

Mobile element dynamics in seven alleles of the chalcone synthase D locus (CHS-D) of the common morning glory (Ipomoea purpurea) are analyzed in the context of synonymous nucleotide sequence distances for CHS-D exons. By using a nucleotide sequence of CHS-D from the sister species Ipomoea nil (Japanese morning glory [Johzuka-Hisatomi, Y., Hoshino, A., Mori, T., Habu, Y. & Iida, S. (1999) Genes Genet. Syst. 74, 141–147], it is also possible to determine the relative frequency of insertion and loss of elements within the CHS-D locus between these two species. At least four different types of transposable elements exist upstream of the coding region, or within the single intron of the CHS-D locus in I. purpurea. There are three distinct families of miniature inverted-repeat transposable elements (MITES), and some recent transpositions of Activator/Dissociation (Ac/Ds)-like elements (Tip100), of some short interspersed repetitive elements (SINEs), and of an insertion sequence (InsIpCHSD) found in the neighborhood of this locus. The data provide no compelling evidence of the transposition of the mites since the separation of I. nil and I. purpurea roughly 8 million years ago. Finally, it is shown that the number and frequency of mobile elements are highly heterogeneous among different duplicate CHS loci, suggesting that the dynamics observed at CHS-D are locus-specific.

Exon shuffling and the origin of the mitochondrial targeting function in plant cytochrome c1 precursor.

Since most of the examples of "exon shuffling" are between vertebrate genes, the view is often expressed that exon shuffling is limited to the evolutionarily recent lineage of vertebrates. Although exon shuffling in plants has been inferred from the analysis of intron phases of plant genes [Long, M., Rosenberg, C. & Gilbert, W. (1995) Proc. Natl. Acad. Sci. USA 92, 12495-12499] and from the comparison of two functionally unknown sunflower genes [Domon, C. & Steinmetz, A. (1994) Mol. Gen. Genet. 244, 312-317], clear cases of exon shuffling in plant genes remain to be uncovered. Here, we report an example of exon shuffling in two important nucleus-encoded plant genes: cytosolic glyceraldehyde-3-phosphate dehydrogenase (cytosolic GAPDH or GapC) and cytochrome c1 precursor. The intron-exon structures of the shuffled region indicate that the shuffling event took place at the DNA sequence level. In this case, we can establish a donor-recipient relationship for the exon shuffling. Three amino terminal exons of GapC have been donated to cytochrome c1, where, in a new protein environment, they serve as a source of the mitochondrial targeting function. This finding throws light upon an old important but unsolved question in gene evolution: the origin of presequences or transit peptides that generally exist in nucleus-encoded organelle genes.

Distribución de la gineta (Geneta geneta Linnaeus, 1758) en el Parque Natural de la Sierra de Mariola (C. Valenciana)

Este trabajo de investigación es pionero y original ya que nunca antes se ha realizado un estudio de la gineta (Genetta genetta) dentro del ámbito valenciano y más concretamente sobre la relación de su distribución con los factores geográficos que la condicionan en el PN Sierra de Mariola. Un mejor conocimiento de su ocupación en el espacio será de interés para la definición de medidas de gestión de fauna del Parque. Utilizando técnicas de fototrampeo se han recopilado 95.372 imágenes con algún contacto animal. De estas imágenes, el 0,10% de las fotografías registradas son de gineta y se ha detectado su presencia en 8 de las 63 cuadrículas (4 Km2) del PN Sierra de Mariola (12,70%). Este estudio ha permitido integrar la información recopilada en campo con las bases de datos existentes para concluir que la situación de la gineta en Sierra de Mariola no es preocupante.

Logical Modeling and Dynamical Analysis of Cellular Networks

The logical (or logic) formalism is increasingly used to model regulatory and signaling networks. Complementing these applications, several groups contributed various methods and tools to support the definition and analysis of logical models. After an introduction to the logical modeling framework and to several of its variants, we review here a number of recent methodological advances to ease the analysis of large and intricate networks. In particular, we survey approaches to determine model attractors and their reachability properties, to assess the dynamical impact of variations of external signals, and to consistently reduce large models. To illustrate these developments, we further consider several published logical models for two important biological processes, namely the differentiation of T helper cells and the control of mammalian cell cycle.

Theologia moralis : iuxta sacrae scripturae, canonum, [et] ss. patrum mentem ... /

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Theologia moralis : iuxta sacrae scripturae canonum et sanctorum patrum mentem /

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Theologia moralis : juxta sacrae scripturae canonum et sanctorum patrum mentem /

Mode of access: Internet.

Theologia moralis : juxta sacrae scripturae canonum et sanctorum patrum mentem /

Mode of access: Internet.

Theologia moralis : juxta sacrae scripturae canonum et sanctorum patrum mentem /

Mode of access: Internet.

Theologia moralis, seu Resolutio casuum conscientiae, juxta sacrae scripturae, canonum, et sanctorum patrum mantem ... ; Tomus secundus ...

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Chinki : historia cochinchinesa, útil y aplicable á otros paises /

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Theologia moralis, seu Resolutio casuum conscientiae, juxta sacrae scripturae, canonum, et sanctorum patrum mantem ... /

Mode of access: Internet.

Theologia moralis, seu Resolutio casuum conscientiae, juxta sacrae scripturae, canonum, et sanctorum patrum mantem ... ; Tomus quartus ...

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Theologia moralis, seu Resolutio casuum conscientiae, juxta sacrae scripturae, canonum, et sanctorum patrum mantem ... ; Tomus sextus ...

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Address on the means of opening new sources of wealth for the northern states. Delivered on the 19th October, 1821, before the Agricultural Society of the County of Rensselaer, and the public attending their proceedings,

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