Studio portrait of Louis Gottschalk.

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Portrait of Louis Gottschalk, Julia Rothschild, Henriette Rothschild und Jenny Rothschild looking at photo album.

From left to right: Julia Rothschild, Henriette Rothschild, Jenny Rothschild; Louis Gottschalk stanting

Obituary of Louis Gottschalk; Hannoversches Tageblatt.

Death Notice of Louis Gottschalk, Hannoversches Tageblatt, Tuesday, Aug 18, 1914

Portrait of George Louis Wolff (Gerd Ludwig Wolff) holding a mouse in his genetics laboratory; Little Rock, Arkansas.

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Reproduction of newspaper obituary for Louis Gottschalk in the Hannoversches Tageblatt.

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Portrait of George Louis Wolff (Gerd Ludwig Wolff) holding a mouse in his genetics laboratory; Little Rock, Arkansas.

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Studio portrait of Louis Gottschalk.

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Genetic studies of body mass index yield new insights for obesity biology

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10−8), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ~2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.

Reproduction of portrait of Louis Levinson.

Husband of Aurelie Levinson nee Roos who was deported to Riga 6 December 1941

Exterior view of the residence of brother-in-law Louis; Wolfenbuettel.

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Portrait of Jacques Offenbach Portraits Men

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Obituary of Louis Gottschalk; Hannoversches Tageblatt.

Death Notice of Louis Gottschalk, Hannoversches Tageblatt, Tuesday, Aug 18, 1914

Portrait of George Louis Wolff (Gerd Ludwig Wolff) holding a mouse in his genetics laboratory; Little Rock, Arkansas.

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Reproduction of newspaper obituary for Louis Gottschalk in the Hannoversches Tageblatt.

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Reproduction of portrait of Louis Levinson.

Husband of Aurelie Levinson nee Roos who was deported to Riga 6 December 1941