Rāikān sadet phrarātchadamnœ̄n līap Monthon Phūket : Phraphutthasakkarāt 2460.

In Thai.

Makrya ap' ton kosmo, ki' alla diēgēmata.

Mode of access: Internet.

Batsʻatrutʻiwn chʻapʻutsʻ ew kshṛotsʻ nakhneatsʻ : aṛajnordutʻeamb Epipʻanu, Khorenatsʻwoy ew Shirakatsʻwoy /

Haṛajabanutʻiwn -- Epiphaniou Peri metrōn kai stathmōn = Epipʻanu Haghags chʻaputsʻ ew kshṛotsʻ -- Anania Shirakunoy hamaroghi Haghags kshṛotsʻn ew chʻapʻutsʻ -- Movsisi Khorenatsʻwoy Haghags asparisakan chʻapʻu -- Haghags ěntʻatsʻitsʻ aregakan ew hamaroy chʻapʻutsʻ ěst krkin ōrinakatsʻ Shirakatsʻwoyn -- Batsʻatrutʻiwn chʻapʻuts ew kshṛotsʻ nakhneatsʻ -- Ard i chʻapʻkʻ ew kshiṛkʻ Gaghghiatsʻwotsʻ -- Aṛandzin dasakargutʻiwn kshṛotsʻ ew chʻapʻutsʻ handerdz tachkakan baṛiwkʻ.

Hanes Cymru, a chenedl y Cymry, o'r cynoesoedd hyd at farwolaeth Llewelyn ap Gruffydd; ynghyd a rhai cofiaint perthynol i'r amseroedd o'r pryd hynny i waered ...

Appeared in fourteen parts, 1836-1842.

L'infinité divine depuis Philon le juif jusqu'a Plotin (Ier s. av. J.-C.-IIIe s. ap. J.-C.) : avec une introduction sur le même sujet dans la philosophie grecque avant Philon le juif /

Bibliography: p. [ix]-xii.

Farmacia, biblioteca e archivio del Convento di s. Maria di Castello. Le chiese rurali di s. Luca, s. Vito e di s. Chiara in Albaro e della parrocchiale di s. Giacomo Ap. in Cornigliano ligure presso Genova.

Italian or Latin.

UM, 1948 Football AP Poll headline

[It's Final: "M" First in Nation"]

Publication AP.

Chemical abstracts

Emrys ap Iwan : Dysgawdr, Llenor, Cenedlgarwr /

Includes index.

Fragm. lat. I 49 - Graduale (Oct.ap. - Apollinaris; Ass. BMV - Bartholomaei)

Trägerband: 'E. lin. 4. N. 5'; Vorbesitzer: Karmeliterkloster Frankfurt am Main

Fragm. lat. I 52 - Missale (Paulus ap.)

Vorbesitzer: Dominikanerkloster Frankfurt am Main

AP-2 transcription factor family member expression, activity, and regulation in human epidermal keratinocytes in vitro

The AP-2 transcription factor family is presumed to play an important role in the regulation of the keratinocyte squamous differentiation program; however, limited functional data are available to support this. In the present study, the activity and regulation of AP-2 were examined in differentiating human epidermal keratinocytes. We report that (1) AP-2 transcriptional activity decreases in differentiated keratinocytes but remains unchanged in differentiation-insensitive squamous cell carcinoma cell lines, (2) diminished AP-2 transcriptional activity is associated with a loss of specific DNA-bound AP-2 complexes, and (3) there is an increase in the ability of cytoplasmic extracts, derived from differentiated keratinocytes, to phosphorylate AP-2alpha and AP-2beta when cells differentiate. In contrast, extracts from differentiation-insensitive squamous cell carcinoma cells are unable to phosphorylate AP-2 proteins. Finally, the phosphorylation of recombinant AP-2alpha by cytosolic extracts from differentiated keratinocytes is associated with decreased AP-2 DNA-binding activity. Combined, these data indicate that AP-2 trans-activation and DNA-binding activity decrease as keratinocytes differentiate, and that this decreased activity is associated with an enhanced ability to phosphorylate AP-2alpha and beta.

Regulation of MAPK activation, AP-1 transcription factor expression and keratinocyte differentiation in wounded fetal skin

Fetal epithelium retains the ability to re-epithelialize a wound in organotypic culture in a manner not dependent on the presence of underlying dermal substrata. This capacity is lost late in the third trimester of gestation or after embryonic day 17 (E-17) in the rat such that embryonic day 19 (E-19) wounds do not re-epithelialize. Moreover, wounds created in E-17 fetuses in utero heal in a regenerative, scar-free fashion. To investigate the molecular events regulating re-epithelialization in fetal skin, the wound-induced expression profile and tissue localization of activator protein 1 (AP-1) transcription factors c-Fos and c-Jun was characterised in E-17 and E-19 skin using organotypic fetal cultures. The involvement of mitogen-activated protein kinase (MAPK) signaling in mediating wound-induced transcription factor expression and wound re-epithelialization was assessed, with the effect of wounding on the expression of keratinocyte differentiation markers determined. Our results show that expression of AP-1 transcription factors was induced immediately by wounding and localized predominantly to the epidermis in E-17 and E-19 skin. c-fos and c-jun induction was transient in E-17 skin with MAPK-dependent c-fos expression necessary for the re-epithelialization of an excisional wound in organotypic culture. In E-19 skin, AP-11 expression persisted beyond 12 h post-wounding, and marked upregulation of the keratinocyte differentiation markers keratin 10 and loricrin was observed. No such changes in the expression of keratin 10 or loricrin occurred in E-17 skin. These findings indicate that re-epithelialization in fetal skin is regulated by wound-induced AP-1 transcription factor expression via MAPK and the differentiation status of keratinocytes.