Genome-Wide Analysis Reveals Selection for Important Traits in Domestic Horse Breeds

Intense selective pressures applied over short evolutionary time have resulted in homogeneity within, but substantial variation among, horse breeds. Utilizing this population structure, 744 individuals from 33 breeds, and a 54,000 SNP genotyping array, breed-specific targets of selection were identified using an FST-based statistic calculated in 500-kb windows across the genome. A 5.5-Mb region of ECA18, in which the myostatin (MSTN) gene was centered, contained the highest signature of selection in both the Paint and Quarter Horse. Gene sequencing and histological analysis of gluteal muscle biopsies showed a promoter variant and intronic SNP of MSTN were each significantly associated with higher Type 2B and lower Type 1 muscle fiber proportions in the Quarter Horse, demonstrating a functional consequence of selection at this locus. Signatures of selection on ECA23 in all gaited breeds in the sample led to the identification of a shared, 186-kb haplotype including two doublesex related mab transcription factor genes (DMRT2 and 3). The recent identification of a DMRT3 mutation within this haplotype, which appears necessary for the ability to perform alternative gaits, provides further evidence for selection at this locus. Finally, putative loci for the determination of size were identified in the draft breeds and the Miniature horse on ECA11, as well as when signatures of selection surrounding candidate genes at other loci were examined. This work provides further evidence of the importance of MSTN in racing breeds, provides strong evidence for selection upon gait and size, and illustrates the potential for population-based techniques to find genomic regions driving important phenotypes in the modern horse. © 2013 Petersen et al.

Association between energy cost of walking, muscle activation, and biomechanical parameters in older female fallers and non-fallers

Objective: To determine the nervous activation, muscle strength, and biomechanical parameters that influence the cost of walking in older fallers and non-fallers. Methods: Maximal voluntary isokinetic torque was measured for the hip, knee and ankle of older women. Oxygen consumption was measured at rest and during 8 min of walking at self-selected speed. An additional minute of walking was performed to collect kinematic variables and the electromyographic signal of trunk, hip, knee, and ankle muscles, which was analyzed by the linear envelope. Cost of walking was calculated by subtracting resting body mass-normalized oxygen consumption from walking body mass-normalized oxygen consumption. Stride time and length, and ankle and hip range of motion were calculated from kinematic data. Findings: Older adult fallers had 28% lower knee extensor strength (p = 0.02), 47% lower internal oblique activation at heel contact (p = 0.03), and higher coactivation between tibialis anterior and gastrocnemius lateralis in each of the gait phases (p < 0.05). For fallers, a higher activation of gluteus maximus was associated with a higher cost of walking (r = 0.55, p < 0.05 and r = 0.71, p < 0.01, before and after heel contact, respectively). For non-fallers, an association between cost of walking and age (r = 0.60, p = 0.01) and cost of walking and thigh muscle coactivation (r = 0.53, p = 0.01) existed. Interpretation: This study demonstrated that there may be links between lower-extremity muscle weakness, muscle activation patterns, altered gait, and increased cost of walking in older fallers. © 2013 Elsevier Ltd. All rights reserved.

Intercropping time of corn and palisadegrass or guineagrass affecting grain yield and forage production

Intercropping corn (Zea mays L.) with forages, such as palisadegrass {Urochloa brizantha (Hochst. ex A. rich.) r. D. Webster [syn. Brachiaria brizantha (Hochst. ex A. rich.) Stapf]} or guineagrass [Megathyrsus maximus (Jacq.) B. K. Simon & S. W. L. Jacobs (syn. Panicum maximum Jacq.)], provides large amounts of biomass for use as straw in no-tillage systems or as pasture. However, it is important to evaluate what time these forages have to be sown into corn systems to avoid reductions in both corn and forage production. This study, conducted for three growing seasons at Botucatu, Brazil, evaluated nutrient concentration and yield of corn as affected by time of forage intercropped as well as forage's dry matter production. our data showed that intercropping systems did not reduce leaf nutrient concentrations and grain yield of corn in relation to sole corn. The simultaneous intercropping of corn and guineagrass resulted in the lowest plant population (51, 200 plant ha-1), number of ears per plant (1.0), and, consequently, the lowest corn grain yield (9801 kg ha-1). Guineagrass seeded at the time of corn fertilizer topdressing resulted in the highest plant population (59, 400 plants ha-1), number of ears per plant (1.2), and corn grain yield (12, 077 kg ha-1). Forage production was highest when intercrop was done simultaneously. palisadegrass could be intercropped with corn both simultaneously or at topdressing fertilization stage. In contrast, it is recommended that guineagrass should only be intercropped with corn at topdressingfertilization. © Crop Science Society of America.

Fisioterapia Aquática na Transferência do Sentado para Ortostatismo no Paciente com AVC: Relato de Caso

Introduction. Studies show that 70% of body weight in patients with stroke during the transfer from sitting to standing position is transferred to the uninvolved limb. Significantly interfering with activities of daily living. Objective. The influence of aquatic therapy on eight in the affected hemisphere during the transition from sitting to standing. Method. Participated in this study a patient with right hemiparesis, the protocol lasted eight sessions in a liquid medium. The data of activation of the gluteus muscle were collected from surface electromyography and data as the weight transfer was examined by baropodometry platform. Results. Initial electromyography (151.1uv right gluteus maximus and left gluteus maximus 229.1uv) and Final electromyography (113.6 uv right gluteus maximus and left gluteus maximus113.3uv). Evolution was 19% in weight transferin paretic hemibody compared the pre and post intervention. Conclusion. The results showed that treatment was favorable to the patient, because at the end of application of the observed activation of the gluteus maximus and improved weight-bearing, and consequently these factors interfered positively in the security and independe in transferring from sitting to standing position.

Análise do Comportamento Eletromiográfico dos Músculos Estabilizadores Primários e a Relação com a Capacidade Física Funcional de Indivíduos Assintomáticos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Mapeamento geoambiental com imagem de satélite do Vale do Paraíba

Pós-graduação em Geociências e Meio Ambiente - IGCE

Seletividade de nicosulfuron isolado e em mistura com atrazine para trinta híbridos comerciais de milho

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação dinamométrica e eletromiográfica do quadril em idosas caidoras e não caidoras

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

Co-contração e onset muscular durante o desequilíbrio de idosas caidoras e não-caidoras

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

Efeitos da manipulação sacroilíaca sobre a simetria e a mobilidade lombopélvica na avaliação radiológica e na realização da marcha

Pós-graduação em Ciências da Motricidade - IBRC

Evolução cromossômica na Ordem Xenarthra

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Respostas de híbridos de milho a sub doses de glyphosate

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Electromyographic reaction time in older female fallers and non-fallers after postural perturbation

O tempo de reação eletromiográfica (TRE) reflete a magnitude e a velocidade com que os músculos são ativados para realizar movimentos, evitar lesões ou posicionar uma articulação e pode ser avaliado após uma perturbação externa para análise do desempenho do controle postural e relacioná-lo com a possibilidade de quedas em idosos. O objetivo do estudo foi verificar o TRE dos músculos oblíquo interno (OI), reto femoral (RF), vasto lateral (VL), tibial anterior (TA), multífido (MU), glúteo máximo (GM), bíceps femoral (BF) e gastrocnêmio lateral (GL) em situações de perturbação do equilíbrio em idosos com e sem histórico de quedas. Para isso, foram avaliadas vinte e nove mulheres com 60 anos ou mais, fisicamente ativas e não-institucionalizadas e separadas em dois grupos de acordo com o relato de quedas nos 12 meses pregressos ao estudo: Grupo de Idosas Caidoras (GIC) (n=13; 72,4 ± 8,0 anos) e Grupo de Idosas Não-Caidoras (GINC) (n=16; 67,8 ± 6,8 anos). O TRE dos músculos avaliados durante o teste de desequilíbrio postural anterior e posterior não foram significativamente diferentes entre os grupos. Os resultados sugerem que a ativação muscular dos músculos avaliados, tanto durante o desequilíbrio anterior quanto no desequilíbrio posterior, não podem ser considerados um fator determinante para quedas.

Utilização de maturadores para antecipação da colheita do milho

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

Influência de protocolos de treino de equilíbrio no desempenho funcional de idosas com osteoporose

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)