Pharmacometrics of neuromuscular blocking agents in anesthetized patients and animals : impact of dose and intravascular mixing phase

Thèse numérisée par la Division de la gestion de documents et des archives de l'Université de Montréal

Toxicity of Effluent from a Titanium Dioxide Factory on some Marine Animals

Toxicity of effluent from a titanium dioxide factory containing sulphuric acid residue with soluble iron metallic salts and insoluble material such as silica, etc. on fishes, decapods and molluscs was studied. The effluent caused changes in pH and oxygen depletion of the sea water. Sublethal effects of the precipitate of ferrous salts were also studied. Dilutions of effluent up to 1:150 were LC100 for all organisms used while 1:200 dilution was LC50 for fishes at 36 hr and for other organisms at 48 hr. But death of organisms at this concentration was caused by pH changes and oxygen depletion and did not account for the effects of the precipitate. Below this level precipitation started soon after mixing with sea water causing death of organisms by choking their gills and siphons. Dilutions,< 1:1000 were 96 hr LCO.

Glycogen degrading enzymes and their regulation in benthic animals and estuarine fish

Alpha glucan phosphorylase plays a very significant role in glycolysis. The inhibition and activation of this enzyme have significant effect on the rate of glycolysis. The rate of glycolysis is also determined by the interconversion between the active 3 and inactive Q forms of phosphorylase by two specific enzymes called phosphorylase phosphatase and phosphorylase kinase. The allosteric properties and interconversion mechanism reported for well—studied animal muscle phosphorylases do not fall under a general pattern. Studies using purified phosphorylase from marine sources are scanty. Detailed studies using specialised tissues from more marine animals are necessary to find the factors that control the properties and activities of the enzyme. This thesis is an attempt in this direction. The thesis deals with a detailed study of the control of the phosphorylase by both allosterism and interconversion between the g and b forms from four different aquatic animals of different habitat. Phosphorylase frm the four different animal muscles were purified either partially or completely and the kinetic and control properties were studied.

Enlarging a training set for genomic selction by imputation of un-genotyped animals in populations of varying genetic architecture

Background: The most common application of imputation is to infer genotypes of a high-density panel of markers on animals that are genotyped for a low-density panel. However, the increase in accuracy of genomic predictions resulting from an increase in the number of markers tends to reach a plateau beyond a certain density. Another application of imputation is to increase the size of the training set with un-genotyped animals. This strategy can be particularly successful when a set of closely related individuals are genotyped. ----- Methods: Imputation on completely un-genotyped dams was performed using known genotypes from the sire of each dam, one offspring and the offspring’s sire. Two methods were applied based on either allele or haplotype frequencies to infer genotypes at ambiguous loci. Results of these methods and of two available software packages were compared. Quality of imputation under different population structures was assessed. The impact of using imputed dams to enlarge training sets on the accuracy of genomic predictions was evaluated for different populations, heritabilities and sizes of training sets. ----- Results: Imputation accuracy ranged from 0.52 to 0.93 depending on the population structure and the method used. The method that used allele frequencies performed better than the method based on haplotype frequencies. Accuracy of imputation was higher for populations with higher levels of linkage disequilibrium and with larger proportions of markers with more extreme allele frequencies. Inclusion of imputed dams in the training set increased the accuracy of genomic predictions. Gains in accuracy ranged from close to zero to 37.14%, depending on the simulated scenario. Generally, the larger the accuracy already obtained with the genotyped training set, the lower the increase in accuracy achieved by adding imputed dams. ----- Conclusions: Whenever a reference population resembling the family configuration considered here is available, imputation can be used to achieve an extra increase in accuracy of genomic predictions by enlarging the training set with completely un-genotyped dams. This strategy was shown to be particularly useful for populations with lower levels of linkage disequilibrium, for genomic selection on traits with low heritability, and for species or breeds for which the size of the reference population is limited.

Propuesta de sistema de gestión de residus sólidos urbanos y ubicación del relleno sanitario en Lucre-Huacarpay, Perú

La problemàtica ambiental més important en la majoria de comunitats de Lucre (Perú), és l’absència d’ un sistema de sanejament apropiat. Es fa una proposta per a la gestió dels residus sòlids urbans per tal de millorar les greus deficiències que repercuteixen directament en la salut dels habitants d’aquestes poblacions

Anàlisi de la situació dels residus d’aparells elèctrics i electrònics (RAEE) al Gironès

Estudi de la situació dels residus d’aparells elèctrics i electrònics al Gironès reformulant la seva gestió actual, valorant si caldria fer una nova planta, així com una campanya de sensibilització social i construcció d’una possible planta intermediària de triatge de RAEE per a la comarca del Gironès

Els organismes animals del litoral gironí

Article que descriu els organismes animals del litoral gironí

L'educaci?? ambiental : els residus s??lids urbans. 'La educaci??n ambiental : los residuos s??lidos urbanos'

Experiencia sobre la problem??tica de los residuos s??lidos dirigida al tercer ciclo de primaria, aunque incluya actividades en las que participa todo el colegio. Se destaca la importancia del respeto al medio ambiente, y como sensibilizar los alumnos para conseguir unos ciudadanos responsables y concienciados sobre la conservaci??n y preservaci??n del medio a trav??s de visitas escolares y trabajo cooperativo en clase y en casa.

L'anàlisi dels residus sòlids domèstics. 'El análisis de los residuos sólidos domésticos'.

La problemática de los residuos sólidos, ya sean urbanos, industriales, domésticos o turísticos es sin duda uno de los problemas más graves que padecen las Islas Baleares. El alumnado en general está poco concienciado sobre esta problemática y aunque los hábitos de recogida de materiales reciclables han mejorado mucho, y una buena proporción de familias separa papel y vidrio del resto de residuos, deben llevarlos hasta los puntos de recogida selectiva. Los hábitos de la gente en relación con la generación de residuos distan mucho de ser los ideales, en parte por la falta de conocimiento global del problema así como su enfoque científico. En este artículo se describe una actividad realizada en el IES Berenguer d'Anoia, en el marco de una optativa del segundo ciclo de ESO dedicada al análisis de la contaminación desde una perspectiva científica. La actividad consiste en analizar los residuos que produce una familia durante toda la semana, clasificarlos, pesarlos y medir el volumen. Se pretende poner de manifiesto la contribución particular de cada casa al problema de los residuos solidos para activar el cambio de hábitos y potenciar procedimientos aplicables a muchas áreas de ESO.

Companion Animals

A simple PowerPoint used as the basis for podcast exercises

La gestió dels residus perillosos i especials als centres educatius. 'La gestión de los residuos peligrosos y especiales en los centros educativos'.

Resumen tomado de la publicación

L'ambientalització dels centres educatius : els residus. 'La ambientalización de los centros educativos : los residuos'.

Resumen tomado parcialmente de la revista

Desemparança apresa i atribucions causals : un exemple de modulació de l'extrapolació a partir de les dades obtingudes en la recerca amb animals. 'Desamparo aprendido y atribuciones causales : un ejemplo de modulación de la extrapolación a partir de los datos obtenidos en la investigación con animales'.

Resumen tomado parcialmente de la publicación

Reciclam residus, reisertam persones. 'Reciclamos residuos, reinsertamos personas'.

Resumen tomado de la revista