966 resultados para Man in the Iron Mask


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Preface.--The forgotten man; and address delivered ... 1897, at Greensboro, N.C.--The school that built a town; an address delivered ... 1901, at Athens, Ga.--The rebuilding of old commonwealths; republished from the Atlantic monthly, for May, 1902

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Translation of: Le vicomte de Bragelonne.

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Mode of access: Internet.

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Mode of access: Internet.

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"Prepared under the direction of the Sub-committee on labor relations of the Industrial relations committee." - Pref.

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Title on added t.p.: The rights of man in the West Indies.

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Attributed to Collins in the National Union Catalog and in Richard H. Shoemaker, A Checklist of American Imprints for 1821.

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DUE TO COPYRIGHT RESTRICTIONS ONLY AVAILABLE FOR CONSULTATION AT ASTON UNIVERSITY LIBRARY WITH PRIOR ARRANGEMENT

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Characters’ identities are integral to how audiences relate to them. But what happens when the character suddenly alters his or her outward appearance? Are they still the same person? This thesis seeks to argue that disguise does not alter a character’s true nature, as evidenced by Pyrocles in Sir Philip Sidney’s The Countess of Pembroke’s Arcadia and the Prince in Margaret Cavendish’s The Convent of Pleasure. Both Pyrocles’ suit of Philoclea and the Prince’s suit of Lady Happy are successful because, however subversive they appear at first, they ultimately adhere to societal norms of the time. The relationship between the cross-dressed prince and his love interest in both works only appears to subvert heteronormative expectations for the time, but ultimately adheres to these societal norms once the disguised character’s true identity is revealed to his chosen partner.

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The splicing factor SF3B1 is the most frequently mutated gene in myelodysplastic syndromes (MDS), and is strongly associated with the presence of ring sideroblasts (RS). We have performed a systematic analysis of cryptic splicing abnormalities from RNA sequencing data on hematopoietic stem cells (HSCs) of SF3B1-mutant MDS cases with RS. Aberrant splicing events in many downstream target genes were identified and cryptic 3' splice site usage was a frequent event in SF3B1-mutant MDS. The iron transporter ABCB7 is a well-recognized candidate gene showing marked downregulation in MDS with RS. Our analysis unveiled aberrant ABCB7 splicing, due to usage of an alternative 3' splice site in MDS patient samples, giving rise to a premature termination codon in the ABCB7 mRNA. Treatment of cultured SF3B1-mutant MDS erythroblasts and a CRISPR/Cas9-generated SF3B1-mutant cell line with the nonsense-mediated decay (NMD) inhibitor cycloheximide showed that the aberrantly spliced ABCB7 transcript is targeted by NMD. We describe cryptic splicing events in the HSCs of SF3B1-mutant MDS, and our data support a model in which NMD-induced downregulation of the iron exporter ABCB7 mRNA transcript resulting from aberrant splicing caused by mutant SF3B1 underlies the increased mitochondrial iron accumulation found in MDS patients with RS.Leukemia advance online publication, 17 June 2016; doi:10.1038/leu.2016.149.

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In questa tesi sperimentale si vuole evidenziare le vulnerabilità informatiche dell’architettura di rete TCP/IP. Nella sicurezza informatica spesso si dà grande rilevanza a software come gli antivirus, o ai dispositivi come i firewall, mentre si sottovaluta di mettere in sicurezza l’architettura di rete stessa. Di fatto nonostante un utente possa utilizzare un sistema operativo o un browser ritenuto estremamente sicuro, se l’amministratore di una rete non ha messo in sicurezza la rete stessa, qualunque operazione di protezione del sistema operativo (OS) o del browser risulta vana. Oltre a dimostrare che qualunque OS e browser possa essere facilmente infettato se non è stata messa in sicurezza la rete in cui naviga, si dimostrerà anche che i protocolli ritenuti sicuri come HTTPS non siano esenti da vulnerabilità. Gli attacchi informatici che si andranno a sperimentare fanno parte della tipologia Man In The Middle. L’attaccante sarà inserito all’interno della rete locale, è per questo motivo che il firewall non potrà effettuare qualunque azione di controllo. In una media/grande impresa è abbastanza frequente avere l’accesso al Wi-Fi, ad esempio come cliente nella sala d’aspetto. Spesso questa connessione Wi-Fi non è isolata dalla rete utilizzata dalla stessa azienda. In questa tesi si andranno ad evidenziare le gravi criticità di cui una configurazione del genere è afflitta. In conclusione, dopo aver analizzato le vulnerabilità dell’architettura di rete TCP/IP, si andranno ad analizzare quali funzioni attivare, e come attivarle, all’interno di switch professionali come Aruba 2930F o router board semiprofessionali come il Mikrotik 750, per mettere in sicurezza una rete locale da questo tipo di attacchi informatici.

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Material no publicado. La documentación se presenta en formato electrónico y en papel

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Plates accompanied by guard sheets with descriptive letterpress.