Produção de lipase por Fusarium oxysporum em fermentação em estado sólido e sua aplicação em reações de síntese de ésteres de biodiesel

Pós-graduação em Ciências Biológicas (Microbiologia Aplicada) - IBRC

Detecção molecular de Paracoccidioides brasiliensis em amostras de tecido e sangue periférico de pacientes portadores de Pacoccidioidomicose: correlação com perfis histopatológico, sorológicos e produção de TNF-α

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Produzindo para disponibilidade: uma aplicação da Teoria das Restrições em ambientes de produção para estoque

The objective of this paper is to present how the Theory of Constraints has recently been dealing with make to stock environments. This new format introduces interesting innovations in terms of the use of simplified Drum-Buffer-Rope method as well as ways to pull production in environments that produce in advance of demand. It also innovates by creating conditions for providing market opportunities based on the explicit assurance of product availability, hence its name: make to availability (MTA). Although it provides important contributions to production planning and control, articles that have directly addressed this issue have not been identified to date in both national and international journals.

Implementação da eficiência global de equipamento (OEE) no padrão de produção e análise de impactos

Nowadays, there is a need for improvements in production processes for companies to be competitive, as it is an obligation of businesses, it is necessary to know about the production processes accurately, to learn where improvements in work and thus have large impacts results. The calculation of efficiency of production lines is necessary to know as much about the progress of production and for product costing, when the measurement is not suitable, it generates negative impacts on the company. Due to the impact generated by this parameter, the graduation work carry out the study of change in a method that does not include all requirements necessary, by another method known as Overall Equipment Effectiveness, and according to studies, covering various parameters, showing become more consistent. These values are contained in the pattern production which is used to fund the product, thereby also occur financial impacts. Thus the work will study the change along with the analysis of impacts caused by the change

Mapeamento do processo de originação de etanol em uma empresa do setor de distribuição de combustíveis

The market segment of fuel distribution composes an important role in the development of Brazil’s industry and economy. However, it is a sector with intense competitiveness, especially in relation to ethanol. The search for competitive advantage and greater strength to the business are, therefore, of high relevance in this context, in which the concepts of Business Process Management has become more visible. Process Mapping, one of these concepts, has proven “TO BE”a strategic tool for companies which believe in flattening the structure and in the potential benefits that the improvement of its processes can provide. Thus, this work aims to map the process of Ethanol Origination of a company engaged in the distribution of this and other fuel products, and other niche markets. It was understood and designed the macro-process aforementioned and identified failures in subprocess related to it. After applying the method to select priority problems, using risk assessment criteria, five subprocess were identified to receive special action, which consisted in seeking improvements with those involved in the process, in representing its current and ideal models and in defining each department’s responsibilities for the activities in the subprocess proposed form. Thus, it is expected to mitigate mainly two negative effects found in the business: employee’s work overload and company's financial exposure

Variação histórica dos preços e das reservas de petróleo brasileiras e internacionais no período 1992-2011

The oil market is not a common market, and its complexity increases dramatically when considering the strategic and geopolitical involved, thus resulting in large uncertainties and concerns. The attempt to control prices has always been a challenge for the major world powers, since the increase in oil prices benefits the exporting countries, but harms importers, especially those regarded as less developed. Understand and try to predict some strategies adopted up the oil crises is one of the main points of the research, in order to demonstrate how economics can be used as an instrument of power and domination between nations, and how plans and strategies and rearrangements of supply and demand favor the growth of this economy, especially in the current period, with the new Brazilian oil era, beginning with the discovery of pre-salt, amid a context of growing need for the use of oil and its derivatives

Análise da implantação do TPM em uma empresa do ramo farmacêutico

Through observation of the production process industries today, one can encounter the needs of the large uncertainties related improvements and changes in the production environment, a fact that inspired the search for solutions that can respond quickly to these changes. Thus, this paper describes the review of implementation of TPM (total productivity management), which aims to optimize two distinct processes in the Vale do Paraíba´s pharmaceutical industry one of through the pillar of specific improvement. The main objective is to propose an efficient alternative to proposing loss management processes by identifying and eliminating the same in a systematic process. To develop this analysis was necessary to explore concepts of TPM and tools that help in taking data, identification and clarification of the phenomena that cause failures in the process, which were essential to ensure the development of the analysis. The concepts covered are usually presented during an undergraduate degree in Engineering. Data compiled by the analysis are able to serve as a strategic benchmark for decision making by managers, providing alternative response variables and uncertainty of the organizational environment, a fact that facilitates the management of human resources and productive

Evolução tectônica do Trend Badejo-Linguado-Pampo, bacia de Campos (RJ)

The regional geological work for the oil industry, in order to find potential areas for hydrocarbon exploration and understand the geological parameters responsible for the formation of the deposit are known importance. This work fits into that scenario, with regional research with the aid of wells and 2D and 3D seismic sold by DBEP (Database Exploration and Production). Were also used as GeoGraphix software package Landmarks modules Prizm and SeisWork 2D and 3D, and the Surfer 8 and ArcGIS 9.2 with the infrastructure provided by the 05 PRH - ANP with LSGI (Laboratory of Seismic and Geological Interpretation) located at UNESP -- Campus de Rio Claro. The work focuses on study the trend of oil-Badejo-Linguado-Pampo, producing fields since the beginning of offshore holdings. The Campos Basin is now known as the offshore basin of the country more productive, and the high structural Badejo is a structure of great importance in the basin presents itself as largely responsible for the conditioning of hydrocarbon fields Pampo, Linguado and Badejo. Therefore this work also aims to increase knowledge of the region in terms of tectonic and stratigraphic characterize the geometry of the structures associated with this major regional structure. For this we used structural contour maps of the main chrono-horizons, and Isopach maps for the purpose of better understanding the tectono-sedimentary evolution of the Campos Basin locally.

Produção e avaliação da estabilidade de enzimas fúngicas

As enzimas estão presentes em todas as células vivas, onde exercem a função de catalisadores das reações que compõem as vias catabólicas e anabólicas do metabolismo celular. Esses biocatalisadores são moléculas de proteínas e seu poder catalítico está associado à conformação nativa, que depende de condições específicas de pH, temperatura e força iônica do meio. Os micro-organismos são bastante atrativos para a indústria, pois possibilitam a produção de enzimas por processos fermentativos em larga escala com regularidade necessária e simplicidade na requisição nutricional. Assim, embora alguns biocatalisadores sejam extraídos de tecidos animais e vegetais, as enzimas industriais são, em sua maior parte, obtidas a partir de micro-organismos. Este trabalho teve como objetivo a produção das enzimas lipase e β-glucanase a partir dos fungos Aspergillus niger e Trichoderma reesei, respectivamente, em diferentes meios de cultura, para determinar as condições de maior produção da enzima em questão. As enzimas produzidas em agitador orbital foram obtidas a partir da filtração do produto da fermentação, precipitação com sulfato de amônio e liofilização. Após a produção e precipitação a atividade das enzimas e a concentração de proteínas foram quantificadas, os parâmetros cinéticos foram determinados frente a diferentes pHs, temperaturas e força iônica do meio. A lipase apresentou melhor atividade a 30°C e em pH 6,0. A presença dos íons Mg2+ e Zn2+ levaram a um aumento na atividade da enzima. A β-glucanase apresentou maiores atividades quando submetidas a 37°C e pH 5,0. Os íons Mg2+, Cu2+ e Ca2+ induziram melhor a atividade enzimática.

Estudo de caso de controle estatístico de processo: levantamento da variação de espessura de tábuas de pinus

This graduate work approaches the study of Statistical Process Control - SPC, in a stage production of an industrial frame, aiming to use the tool of statistical process control (SPC) to assess the process capability. Where the process needs improvement as well not meet the specifications. Assessing the needs that the company needs to improve quality management, and the difficulties they present during the implementation of the CEP. The present study is to use the method of case study. The results are presented through study, and checking the capacity and stability of the process using control charts XbarraR. The process demonstrated the need for improvements in process and quality management. At the end of the work are presented suggestions for improving the quality system of the company

Campylobacter sp como perigo biológico na produção de peito de frango maturado

Pós-graduação em Microbiologia Agropecuária - FCAV

Adaptação da produção aos objetivos de competitividade e produtividade: a pesquisa-ação em uma manufatureira de cutelaria inserida em rede

One of the oldest segments in operations management, whose models are always subject to development efforts, for academics and productive organizations, is the management of production and work organization. Proposals for strategic management principles that seek to bring production to streamline processes reduce costs and add value, identifying problems with material flow and information while reducing the response time. This is realized through the pursuit of the best actions to achieve goals and targets established in a successful Planning and Production Control. This article aims to identify and implement actions that increase the speed of supply of goods produced in a enterprise cutlery; positively influencing the perception of customers. Such attitudes benefit all actors involved in the network, a fact which is expressed in the production chain. To lay the foundations of research and validate the data obtained, it was a study drawing on action research methodology. The goods produced are sold, mainly to wholesalers. Was proved seven aspects to improve and enhance the competitiveness of the organization, among them the complete design of the network, integrating upstream and downstream actors.

Avaliação do Sistema Simplified Drum-Buffer-Rope em ambientes de produção para estoque

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Métodos de previsão auto-regressivo aplicado a uma série de volume de produção de caminhões

The national truck fleet has expanded strongly in recent decades. However, due to fluctuations in the demand that the market is exposed, it needed up making more effective strategic decisions of automakers. These decisions are made after an evaluation of guaranteed sales forecasts. This work aims to generate an annual forecast of truck production by Box and Jenkins methodology. They used annual data for referring forecast modeling from the year 1957 to 2014, which were obtained by the National Association of Motor Vehicle Manufacturers (Anfavea). The model used was Autoregressive Integrated Moving Average (ARIMA) and can choose the best model for the series under study, and the ARIMA (2,1,3) as representative for conducting truck production forecast

Influência da cultura organizacional na implementação de um programa de melhoria contínua de uma empresa de grande porte

The objective of this study was to identify the facilitators and restrictive factors promoted by the organizational culture on the implementation of a continuous improvement program in a company. The influence of organizational culture on tools used to improve processes and results demonstrate critical factors for international competitiveness, reflecting a company's strategy. Depending on how new working methods are implemented, organizational changes to reduce variation and waste, such as lean production, can affect the employee experience in the workplace and their learning conditions. Changes and formalization of the work process can be coercive, characterized by forced compliance, introduction of rules, and focus on technical and financial methods; or may be favorable, encouraging employee involvement in problem solving and stressing learning and innovation. The basis of the analysis lies with two models for assessing organizational culture - Denison Model and Competing Values Framework. The methodology used was: conducting interviews, a questionnaire, literature review and documentary analysis of a large company equipment industry. Results suggest that organizational culture plays an important role in the adoption of Lean practices. It can contribute to its effectiveness and job satisfaction, but it is not decisive feature of their success. The conclusion is that the organizational culture becomes a driving factor when aligned to the proposed practices and when taken into consideration for planning, acting as a limitation when it does not promote development and a participative environment