Composição e digestibilidade in vitro de genótipos de capim-elefante, aos 56 dias de rebrota

Twelve elephant grass genotypes were evaluated in a randomized blocks design with three repetitions. The experimental parcel was of 4 lines with 3m of length, spaced of 1 m and fertilized with 100 kg of P2O5, 100 kg of N, 60 kg of K2O and 25 kg of micronutrients/ha. Significant differences were observed among the genotypes for neutral detergent fiber (FND), acid detergent fiber (FAD) and lignin. The genotypes CNPGL 92-70-02, CNPGL 91-25-01 and CNPGL 93-32-02 showed low values for FND, FAD and lignin, simultaneously, outstanding between the others. There were no significant differences in the levels of dry matter and crude protein contents and in in vitro dry matter digestibility between the genotypes.

Influence of δβ-thalassemia or regulatory elements in individuals with increased fetal Hb levels in the São Paulo northwest population

Fetal hemoglobin (Hb F), formed by two alpha globin chains (α) and two gamma chains (γ) (α2 γ2), has reduced expression in adults, ranging from 0 to 1% of total hemoglobin. Increased levels of Hb F are due to mutations in the β-globin family, which cause hereditary persistence of fetal hemoglobin (HPFH) and delta-beta thalassemia (δβ-thalassemia).The control of the production takes place by the regulatory region and regions outside the β-globin family, among them 2q16, 6q23, 8q, and Xp22.2.The aims of this study were to determine the presence and frequency of two mutations for δβ-thalassemia, the XmnI polymorphism and β-globin haplotypes in healthy individuals with increased Hb F in the State of São Paulo. We analyzed 60 samples of peripheral blood of healthy adults, without complaints of anemia. The samples were separated into two groups according to Hb F level: group I - 34 samples with Hb F ranging from 2 to 15% and group II - 26 samples with Hb F over 15%. In relation to the polymorphisms examined, we found three heterozygous individuals (5%) for Spanish δβ-thalassemia, belonging to group I, whose Hb F levels were within the normal range.The Sicilian δβ-thalassemia mutation was not found, indicating the need to study other polymorphisms related to the increase of Hb F in adult life.The frequency of XmnI polymorphism was 33.3% and the mean Hb F levels were 15.48 ± 11.69%.The frequency observed in our study for this polymorphic site is higher than that found in the literature for healthy subjects.This polymorphism was more prevalent in individuals with Hb F levels below 15%. For four samples positive for this polymorphism, the Hb F levels were explained by the presence of HPFH and Spanish δβ-thalassemia mutations, so that the presence of the XmnI polymorphic site was not a determinant in the overexpression of γ-globin genes. Regarding β-globin haplotypes, 18 alleles and 27 distinct genotypic patterns were found.The pattern Atp1/Atp2 was the mostfrequent genotype (13.72%).Of the 18 alleles, 13 showed atypical patterns.The results show that the haplotype V was the most frequent (27.45%), followed by atypical Atp2 (13.72%) and Atp1 (11.76%), and that there was a higher correlation with the presence of HPFH and XmnI polymorphism.The high frequency of haplotype V in our samples and high frequency of atypical haplotypes may reflect a high rate of miscegenation in this population, suggesting an ethnic characteristic for the Brazilian population, requiring the evaluation of population genetic markers to corroborate this hypothesis. © FUNPEC-RP.

Evaluation of HPFH and δβ-thalassemia mutations in a Brazilian group with high Hb F levels.

Fetal hemoglobin (Hb F) is characteristic of the fetal development period. However, in some genetic conditions, such as hereditary persistence of fetal hemoglobin (HPFH) and delta-beta thalassemia (δβ-thalassemia), Hb F continues to be produced in adulthood. We evaluated the frequency of two mutations of HPFH, HPFH-1 and HPFH-2 African, and two mutations in δβ-thalassemia, Sicilian and Spanish, in a Brazilian population. Peripheral blood samples were collected from adults from hospitals and blood centers in southeast and northeast Brazil. These individuals were healthy and without complaints of anemia, but had increased Hb F. Samples were submitted to electrophoretic and chromatographic analyses to quantify Hb F values and, subsequently, to molecular analyses to verify the mutations. In the molecular analysis, 16 of the 60 samples showed a heterozygous profile for the HPFH mutations, two for HPFH-1 and 14 for HPFH-2. In the same sample set, three were heterozygous for Spanish δβ-thalassemia and none were heterozygous for Sicilian δβ- thalassemia. The Hb F values in the HPFH-2 heterozygotes differed from those previously reported for this mutation. In this group, the HPFH mutations were more frequent than the δβ-thalassemia mutations. The finding of these mutations in this Brazilian population reflects the mixing process that occurred during its formation.

Aproveitamento de madeiras tropicais para confecção e avaliação de painéis aglomerados com mistura de partículas e resinas alternativas

Pós-graduação em Engenharia Civil - FEIS

ECLAC Notes Nº 56

Special issue about the Preliminary Overview of the Economies of Latin America and the Caribbean 2007 Regional Panorama Opinion by ECLAC's Executive Secretary, José Luis Machinea. Taking Advantage of the Favourable Scenario to Consolidate Economic Growth Macroeconomic Policy Domestic Performance External Sector Macroeconomic Management Should Make the Most of Growth Statistical Appendix Recent Titles Calendar of events

Notas de la CEPAL Nº 56

Edición especial sobre el Balance preliminar de las economías de América Latina y el Caribe 2007. Panorama regionalAprovechar esta coyuntura favorable para consolidar el crecimiento económico de la región. Columna de opinión de José Luis Machinea, Secretario Ejecutivo de la CEPALPolítica macroeconómicaEl desempeño internoSector externoMayor prudencia en la gestión macroeconómica permitirá aprovechar actual etapa de crecimientoApéndice estadísticoPublicaciones recientesCalendario de eventos

Revista de la CEPAL no.56

Democracia y desarrollo / Femando H. Cardoso. -- ¿Es posible crecer con equidad? / Joseph Ramos. -- Estabilidad y estructura: Interacciones en el crecimiento económico / José María Fanelli y Roberto Frenkel. -- Reforma a los sistemas de pensiones en América Latina / Andras Vthoff. -- Tendencias económicas en China: significado para el comercio con América Latina y el Caribe / Mikio Kuwayama. -- El Intercambio económico entre América Latina y las economías dinámicas dé Asia / Ronald Sprout. -- La relación económica entre la América Latina y la Unión Europea / Roberto Smith Perera. -- Nuevas Implicaciones de las reglas de origen / Eduardo Gitli. -- Globalización y reestructuración energética en América Latina / Femando Sánchez Albavera. -- El caleidoscopio de la competitividad / Geraldo Mailer. -- La privatización de los servicios públicos del agua / Miguel Solones. -- ¿Cuánto se puede gastar en educación? / Guillermo Labarca. -- Mujeres y migrantes: desigualdades en el mercado laboral de Santiago de Chile / Ivonne Szasz.

CEPAL Review no.56

Democracy and development / Fernando H. Cardoso. -- Can growth and equity go hand in hand? / Joseph Ramos. -- Stability and structure: interactions in economic growth / José Maria Fanelli and Roberto Frenkel. -- Pension system reform in Latin America / Andras Uthoff. -- Recent economic trends in China and their implications for trade with Latin America and the Caribbean / Mikio Kuwayama. -- Economic relations between Latin America and the high-performing Asian developing economies / Ronald Sprout. -- Economic relations between Latin America and the European Union / Roberto Smith Perera. -- Rules of origin: new implications / Eduardo Gitli. -- Globalization and restructuring the energy sector in Latin America / Femando Sánchez Albavera. -- The kaleidoscope of competitiveness / Geraldo Müller. -- The privatization of public water utilities / Miguel Solones. -- How much can we spend on education? / Guillermo Labarca. -- Women and migrants: inequalities in the labour market of Santiago, Chile / Ivonne Szasz.

Mancha areolada da seringueira (Hevea brasiliensis) na Amazônia: evolução do patógeno (Thanatephorus cucumeris/Rhizoctonia solani grupo de anastomose AG 2-2 Hb) num patossistema tropical

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)