217 resultados para Gero, Markgraf.
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The object theme of the present study is a population of caboclos that absorbed as manual workers in the saw-mills which were mounted in the highland region of Santa Catarina since 1950. The abundance of araucaria (native kind of pine) the opening of markets, and the corroboration of other industrial exploration conditions encouraged a great crowd of small en.- trepreneurs, coming basically from the state of Rio Grande do Sul, to migrate and settle down, building up a lot of saw-mills near rich forests and fields. The saw-mills started aprosperous production of timber sawn in planks. The process of industriali zation was so intensive, the destruction of pine woods soviolent that, in less than three decades, the forests ran out of tree reserves. The caboclos, absorbed as manual workers in production of timber, lived traditionally in an system of subsistense, either from the cultivation of pine the economic their land (planter caboclo) or as labourers in cattle-growing farms (farm hand caboclos). Nevertheless, the 'advantages' that were offered them by the new-comer entrepreneurs (a salary paid in money, a new house in a village, and other favours) helped the great majority of caboclos to abandon their traditional work and enlist as "workmen" in saw-mills. The new job, besides being a novelty, was an opportunity for a change in status. Subsequently, the running out of forests of araucaria and the resultant progressive shut-down of saw-mills caused the crowd of workmen to be out of imployment and to form to form a migratory flood toward the most important town of the region, Lages. The town of Lages, however, having made of the timber i ts main economic support wi thout the implantation of an alternative industry, was unable to offer the migrantssufficient 'work places'. In this way, the 'marginal crowd' began to settle down in the suburbs of the city. This study, in the context of the object theme, analyses two main questions related to the reality 'WOlLQ' and to the economic exploitation forms: ~) the relations of production in the economic regime of subsistence and in the capitalist regime of industrial production with the consequent 'positions' of the workman in the productive processj ~~) the deriving educative effects of the productive process, either in the economic regime of subsistence, or in the capitalist industrial regime. The two questions are theoretically debated andconfro~ ted with the proposed reality, giving origin to conclusions that, in a general formulation, can be summarized as follows: a) the caboclos of the highland region of Santa Catari na, when under an economic regime of subsistence, held in fee the productive processj there was a social division of the work and aclimate of freedom which made possible the development of knowledge from their life and work experience, the production of most of their tools, and the making of necessary manufactures adapted to their own surrounding ditionsi -- - --- other con- ------ b) however, these same caboclos, when absorbed by the capitalist industrial process of production - tipified by the work in saw-mills - lost the control of the productive processj this was caused by the technologic division of the work, since each man began to perform a dull and repeti tive action, directed by the speed of the 'major-saw' j man resigned form his skill and inventive power and surrendered to an executive authority which turned him into a 'collective worker'j the new productive process, besides rnaking each rnan a copy of a pattern, put the caboclos in a situation in which the daily work experiencedidn't add anything in terrns of autogenesis of knowledgei and even the environrnental educative rneans were reduced to new forrns of adaptation to the productive process, relegating rnan's inventive power to inertia.
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We investigate the possibilities of New Physics affecting the Standard Model (SM) Higgs sector. An effective Lagrangian with dimension-six operators is used to capture the effect of New Physics. We carry out a global Bayesian inference analysis, considering the recent LHC data set including all available correlations, as well as results from Tevatron. Trilinear gauge boson couplings and electroweak precision observables are also taken into account. The case of weak bosons tensorial couplings is closely examined and NLO QCD corrections are taken into account in the deviations we predict. We consider two scenarios, one where the coefficients of all the dimension-six operators are essentially unconstrained, and one where a certain subset is loop suppressed. In both scenarios, we find that large deviations from some of the SM Higgs couplings can still be present, assuming New Physics arising at 3 TeV. In particular, we find that a significantly reduced coupling of the Higgs to the top quark is possible and slightly favored by searches on Higgs production in association with top quark pairs. The total width of the Higgs boson is only weakly constrained and can vary between 0.7 and 2.7 times the Standard Model value within 95% Bayesian credible interval (BCI). We also observe sizeable effects induced by New Physics contributions to tensorial couplings. In particular, the Higgs boson decay width into Zγ can be enhanced by up to a factor 12 within 95% BCI. © 2013 SISSA.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Examples are presented of inter-hemispheric comparison of instrumental climate and paleoclimate proxy records from the Americas for different temporal scales. Despite a certain symmetry of seasonal precipitation patterns along the PEP 1 transect, decadal variability of winter precipitation shows different characteristics in terms of amplitude and frequency in both the last 100 and last 1000 years. Such differences in variability are also seen in a comparison of time series of different El Nino/Southern Oscillation proxy records from North and South America, however, these differences do not appear to affect the spatial correlation with Pacific sea surface temperature patterns. Local and regional differences in response to climate change are even more pronounced for records with lower temporal resolution, and inter-hemispheric synchroneity may or may not be indicative of the same forcing. This aspect is illustrated in an inter-hemispheric comparison of the last 1000 years of glacier variability, and of the full- and late-glacial lake level history.
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Plant-sociological and climatic classification of the Australian Nothofagus cunninghamii rain forest provides the basis for a new, semiquantitative approach to interpretations of late-Quaternary paleoclimates from four pollen sequences in southwestern Tasmania. Varying proportions of rain-forest pollen types in the records were related to different modern rain-forest alliances and their specifc climatic regimes, such as Eastern Rain Forest, Leatherwood Rain Forest, and sclerophyllous, Subalpine Rain Forest. According to this interpretation, early Holocene climates were characterized by 1,600 mm annual precipitation and 10°C annual temperature, conditions substantially warmer and drier than previously thought. Maximum precipitation levels of 2,500 mm annually were not reached until 8,000 years B.P. A short-term cooling episode between 6,000 and 5,000 years B.P. led to the establishment of modern rain-forest distribution in western Tasmania, characterized either by a precipitation gradient steeper than before, or by greater climatic variability. To interpret paleoclimates from before 12,000 years B. P., when non-arboreal environments dominated in western Tasmanian bollen records, various modern treeless environments were studied in search for analogs. Contrary to earlier interpretations, late-glacial environments were not alpine tundra with a treeline at modern sea level, but steppe, with marshes or shallow lakes instead of the modern lakes. Climate was characterized by 50% less precipitation than today, resulting in substantial summer droughts. To explain such drastic precipitation decrease, the westerlies that dominate Tasmanian climate today must have been shifted polewards. This suggestion is supported by climate models that take Milankovitch-type insolation differences into account as well as sea-surface temperatures. Paleolimnological information based on diatom analyses support the general paleoclimatic reassessment.
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Antenatal maternal administration of corticosteroids has been shown to reduce morbidity and mortality rates in preterm delivery. Threatened spontaneous or medically indicated preterm delivery for maternal or fetal indications between 24 and 34 weeks of gestation with unknown fetal lung maturity status are indications for antenatal corticosteroid administration. Recent studies have challenged current practice of antenatal glucocorticoid use. The goal of this expert letter is to provide recommendations based for the clinical use of antenatal glucocorticoids based on the current evidence from published studies.
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OBJECTIVE: Virologic failure of HIV-positive patients is of special concern during pregnancy. We compared virologic failure and the frequency of treatment changes in pregnant and non-pregnant women of the Swiss HIV Cohort Study. METHODS: Using data on 372 pregnancies in 324 women we describe antiretroviral therapy during pregnancy. Pregnant women on HAART at conception (n = 131) were matched to 228 non-pregnant women (interindividual comparison) and to a time period of equal length before and after pregnancy (intraindividual comparison). Women starting HAART during pregnancy (n = 145) were compared with 578 non-pregnant women starting HAART. FINDINGS: The median age at conception was 31 years, 16% (n = 50) were infected through injecting drug use and the median CD4 cell count was 489 cells/microl. In the majority of pregnancies (n = 220, 59%), women had started ART before conception. When ART was started during pregnancy (n = 145, 39%), it was mainly during the second trimester (n = 100, 69%). Two thirds (n = 26) of 35 women starting in the third trimester were diagnosed with HIV during pregnancy. The risk of virologic failure tended to be lower in pregnant than in non-pregnant women [adjusted odds ratio 0.52 (95% confidence interval 0.25-1.09, P = 0.08)], but was similar in the intraindividual comparison (adjusted odds ratio 1.04, 95% confidence interval 0.48-2.28). Women starting HAART during pregnancy changed the treatment less often than non-pregnant women. CONCLUSION: Despite the physiological changes occurring during pregnancy, HIV infected pregnant women are not at higher risk of virologic failure.
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BACKGROUND: As only a minority of alcoholics develop cirrhosis, polymorphic genes, whose products are involved in fibrosis development were suggested to confer individual susceptibility. We tested whether a functional promoter polymorphism in the gene encoding matrix metalloproteinase-3 (MMP-3; 1171 5A/6A) was associated liver cirrhosis in alcoholics. METHODS: Independent cohorts from the UK and Germany were studied. (i) UK cohort: 320 alcoholic cirrhotics and 183 heavy drinkers without liver damage and (ii) German cohort: 149 alcoholic cirrhotics, 220 alcoholic cirrhotics who underwent liver transplantation and 151 alcoholics without liver disease. Patients were genotyped for MMP-3 variants by restriction fragment length polymorphism, single strand confirmation polymorphism, and direct sequencing. In addition, MMP-3 transcript levels were correlated with MMP-3 genotype in normal liver tissues. RESULTS: Matrix metalloproteinase-3 genotype and allele distribution in all 1023 alcoholic patients were in Hardy-Weinberg equilibrium. No significant differences in MMP-3 genotype and allele frequencies were observed either between alcoholics with or without cirrhosis. There were no differences in hepatic mRNA transcription levels according to MMP-3 genotype. CONCLUSIONS: Matrix metalloproteinase-3 1171 promoter polymorphism plays no role in the genetic predisposition for liver cirrhosis in alcoholics. Stringently designed candidate gene association studies are required to exclude chance observations.
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Recent evidence suggests that managers establish a positive link between management accounting system (MAS) integration and controllership effectiveness, which is fully mediated by the perceived consistency of financial language. Our paper extends this research by analyzing whether controllers have similar perceptions on MAS design. Testing a series of multi-group structural equation models, we find evidence for a preparer-user perception gap with respect to the mediating impact of a consistent financial language. Our results contribute to the still-ongoing controversial debate on MAS integration by indicating that the effectiveness of MAS design cannot be evaluated solely from an instrumental perspective independent from users’ perceptions.
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Tocolysis is an important treatment in the improvement of outcome in preterm labor and preterm birth, provided that its use follows clear evidence-based recommendations. In this expert opinion, the most recent evidence about efficacy and side effects of different tocolytics is being reviewed and evidence-based recommendation about diagnosis and treatment of preterm labor is given. Further aspects such as progesterone administration or antibiotic treatment for the prevention of preterm birth are included. Our review demonstrates that an individualized choice of different tocolytics and additional treatments is necessary to improve short- and long-term neonatal outcome in preterm labor and preterm birth.