918 resultados para English for Speakers of Other Languages


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In this paper we show that heritage speakers and returnees are fundamentally different from the majority of adult second language learners with respect to their use of collocations (Laufer & Waldman, 2011). We compare the use of lexical collocations involving yap- “do” and et- “do” among heritage speakers of Turkish in Germany (n=45) with those found among Turkish returnees (n=65) and Turkish monolinguals (n=69). Language use by returnees is an understudied resource although this group can provide crucial insights into the specific language ability of heritage speakers. Results show that returnees who had been back for one year avoid collocations with yap- and use some hypercorrect forms in et-, whilst returnees who had been back for seven years upon recording produce collocations that are quantitatively and qualitatively similar to those of monolingual speakers of Turkish. We discuss implications for theories of ultimate attainment and incomplete acquisition in heritage speakers.

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Mutations in the Na+-HCO3- cotransporter NBC1 cause severe proximal tubular acidosis (pRTA) associated with ocular abnormalities. Recent studies have suggested that at least some NBC1 mutants show abnormal trafficking in the polarized cells. This study identified a new homozygous NBC1 mutation (G486R) in a patient with severe pRTA. Functional analysis in Xenopus oocytes failed to detect the G486R activity due to poor surface expression. In ECV304 cells, however, G486R showed the efficient membrane expression, and its transport activity corresponded to approximately 50% of wild-type (WT) activity. In Madin-Darby canine kidney (MDCK) cells, G486R was predominantly expressed in the basolateral membrane domain as observed for WT. Among the previously identified NBC1 mutants that showed poor surface expression in oocytes, T485S showed the predominant basolateral expression in MDCK cells. On the other hand, L522P was exclusively retained in the cytoplasm in ECV304 and MDCK cells, and functional analysis in ECV304 cells failed to detect its transport activity. These results indicate that G486R, like T485S, is a partial loss of function mutation without major trafficking abnormalities, while L522P causes the clinical phenotypes mainly through its inability to reach the plasma membranes. Multiple experimental approaches would be required to elucidate potential disease mechanism by NBC1 mutations.

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Une langue est comme un être vivant. Elle porte les traces des avis, des sentiments, de la joie et des déceptions de nos ancêtres. En même temps elle reflète les toutes tous derniers modes de vie et la manière de penser et d’agir dans la vie quotidienne. Ce sont sa grammaire, ses mots, ses proverbes et ses citations qui en témoignent. Ses sons soulignés par l’intonation et la prosodie nous laissent presque deviner l’esprit de vitalité, de mélancolie ou d’élégance de la langue et de ces locuteurs. Mais est-ce qu’il est possible de trouver aussi les traces des événements historiques et sociaux dans l’évolution d’une langue? Cette question est centrale dans ce mémoire qui suit l’évolution du français à partir du latin parlé dans l’Antiquité et en comparaison avec celle d’autres langues notamment celle du suédois.

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Se refiere a resoluciones que emanan de otros organos de la ONU, incluso la CEPAL, el Consejo Economico y Social y la Asamblea General. El documento pretende llamar a la atencion del Comite las acciones de seguimiento tomadas acerca de ciertos asuntos que el Comite ha considerado en sesiones anteriores y que tengan alguna implicacion directa o indirecta para el CDCC o que sean de interes para el trabajo de la Secretaria.

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Pós-graduação em Estudos Linguísticos - IBILCE