Dictionariu[m] Aelij Antonij Nebrissen[sis] ...

Mode of access: Internet.

Medulla theologiae moralis : facili ac perspicua methodo resoluens casus conscientiae /

Mode of access: Internet.

Additiones, notae, resolutiones ad 7 partit. gloss. et cogita Doct. Gregorii Lopetii /

Portada calcográfica.

Celeberrimi ac moralissimi Sacre ... Magistri Roberti Holkot ... Opus reuera insignissimum in librum Sapie[n]tie Salomonis editum.

Mode of access: Internet.

Scholia palaia ton pany dokimoneis ten Homerou Iliada.

Precedido por 1 h. en cuyo recto aparece: "Lectori Homeri interpres peruetustus..." y en el verso aparecen 2 Epigrammata de J. Lascaris.

Celeberrimi ac moralissimi Sacre ... Magistri Roberti Holkot ... Opus reuera insignissimum in librum Sapie[n]tie Salomonis editum.

CCBE S. XVI,

Viaje del Infante Cardenal don Fernando de Austria : desde 12 de abril 1632 que saliò de Madrid... hasta 4 de Noviembre de 1634 que entró en la de Bruselas /

MTSD 0285.

Michaelis Thomasii Disputationes quaedam ecclesiasticae ...

Contiene según consta en la portada: Brevis christianae ac Catholicae fidei defensio, et Iudaeorum, Mahumetanorum, atque Haereticorum oppugnatio. - De ratione habendi Concilia Prouincialia ac Diocesana, et de iis quae in ipsis praecipue sunt tractanda. - Isidori ordo de celerando Concilio. - De variis Collegiis ad utilitatem publicam constituendis.

Monumenta Ordinis Fratrum Praedicatorum historica.

Vol. 1 has imprint: Lovanii, Typis E. Charpentier & J. Schoonjans.

M. Tvlli Ciceronis Orationes /

[Vol. 3] editio altera recognita et emendata.

De delictis, et poenis tractatus absolutissimus ... /

Mode of access: Internet.

Orationes /

v. 4. The last of this edition. cf. "Praefatio": "Pusillo igitur hoc volumine in lucem exeunte confecta est editio Oxoniensis." In this edition the orations are given in the order of the manuscripts on which the text is based; an edition of the orations in their chronological order may follow at some future time.

Kritische Gänge,

1. Hft. Eine Reise.--2. Hft. Shakspeare in seinem Verhältniss zur deutschen Poesie, insbesonders zur politischen. Shakspeare's Hamlet.--3. Hft. Friedrich Strauss als Biograph. Vernünftige Gedanken über die jetzige Mode. Zum zweiten Theile von Goetheʹs Faust.--4. Hft. Ein Schützengang. Pro domo. Ludwig Uhland.--5. Hft. Kritik meiner Aesthetik. An Herrn Staatsrat Hahn in Petersburg. Ein Gang am Strande.--6. Hft. Kritik meiner Aesthetik (Fortsetzung und Schluss). Eine Schrift über Jean Paul. Die Rottmann-Fresken in München. Offener Brief an den Redakteur des Feuilletons der "Deutschen Zeitung", Dr. Speidel. Der alte und neue Glaube : ein Bekenntnis von D. Fr. Strauss.

Extração, caracterização e avaliação bioativa do extrato de Arrabidaea chica

The use of plants for medicinal purposes is ancient, with widespread application in medicinal drugs. Although plants are promising sources for the discovery of new molecules of pharmacological interest, estimates show that only 17% of them have been studied for their possible use in medicine. Thus, biodiversity of Brazilian flora represents an immense potential for economic use by the pharmaceutical industry. The plant Arrabidaea chica, popularly known as “pariri”, is common in the Amazon region, and it is assigned several medicinal properties. The leaves of this plant are rich in anthocyanins, which are phenolic compounds with high antioxidant power. Antioxidant compounds play a vital role in the prevention of neurological and cardiovascular diseases, cancer and diabetes, among others. Within the anthocyanins found in Arrabidaea chica, stands out Carajurin (6,7-dihydroxy-5,4’- dimethoxy-flavilium), which is the major pigment encountered in this plant. The present work aimed to study on supercritical extraction and conventional extraction (solid-liquid extraction) in leaves of Arrabidaea chica, evaluating the efficiency of the extractive processes, antioxidant activity and quantification of Carajurin contained in the extracts. Supercritical extraction used CO2 as solvent with addition of co-solvent (ethanol/water mixture) and were conducted by the dynamic method in a fixed bed extractor. The trials followed a 24-1 fractional factorial design, the dependent variables were: process yield, concentration of Carajurin and antioxidant activity; and independent variables were: pressure, temperature, concentration of co-solvent (v/v) and concentration of water in the co-solvent mixture (v/v). Yields (mass of dry extract/mass of raw material used) obtained from supercritical extraction ranged from 15.1% to 32%, and the best result was obtained at 250 bar and 40 °C, co-solvent concentration equal to 30% and concentration of water in the co-solvent mixture equal to 50%. Through statistical analysis, it was found that the concentration of co-solvent revealed significant effect on the yield. Yields obtained from conventional extractions were of 8.1% (water) and 5.5% (ethanol). Through HPLC (High-performance liquid chromatography) analysis, Carajurin was quantified in all the extracts and concentration values (Carajurin mass/mass of dry extract) ranged between 1% and 2.21% for supercritical extraction. For conventional extraction, Carajurin was not detected in the aqueous extract, while the ethanol extract showed Carajurin content of 7.04%, and therefore, more selective in Carajurin than the supercritical extraction. Evaluation of antioxidant power (radical 2,2-diphenyl-1-picrylhydrazyl – DPPH – sequestration method) of the supercritical extracts resulted in EC50 values (effective concentration which neutralizes 50% of free radicals) ranged from 38.34 to 86.13 μg/mL, while conventional extraction resulted in EC50 values of 167.34 (water) and 42.58 (ethanol) μg/mL. As for the quantification of total phenolic content (Folin-Ciocalteau analysis) of the supercritical extracts resulted in values ranged from 48.93 and 88.62 mg GAE/g extract (GAE = Gallic Acid Equivalents), while solid-liquid extraction resulted in values of 37.63 (water) and 80.54 (ethanol) mg GAE/g extract. The good antioxidant activity cannot be attributed solely to the presence of Carajurin, but also the existence of other compounds and antioxidants in Arrabidaea chica. By optimizing the experimental design, it was possible to identify the experiment that presented the best result considering the four dependent variables together. This experiment was performed under the following conditions: pressure of 200 bar, temperature of 40 °C, co-solvent concentration equal to 30% and concentration of water in the co-solvent mixture equal to 30%. It is concluded that, within the studied range, it is possible to purchase the optimum result using milder operating conditions, which implies lower costs and greater ease of operation.

Source Provenance of Pre-Historic Granitic Grindstones: The Case Study of the Cogotas I Archaeological Site of Arroyo Mucientes/San Lázaro (Castronuño, Valladolid) and a Proposal on the General Methodological Flow Process

The occurrence of hand grindstones at the Cogotas I archaeological sites is considered to be a common feature. Given that a distant-provenance raw material is frequently involved, determination of its source is a basic factor in the search for a better understanding of resource management and for any Political Economy approach. To progress in these directions an overall study should be planned, using selected grindstones with a view to covering diverse sub-zones of the Cogotas I dispersal area, especially because of its considerable distance from the granite basement source. Such a study may today includes diverse analytical procedures combining successive geographic, petrographic, mineralogical and geochemical criteria. To check the plausibility of the proposed methodology, a preliminary test has been carried out on two granite grindstones, obtained at the archaeological excavation at the Castronuño (Valladolid) Cogotian site, which is fifty km away from an inferred source area that was presumably located at Peñausende (Zamora). The result obtained validates the proposed operational process, yielding a generalizable knowledge to other similar situations.