767 resultados para Biopharmaceutics classification system


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In this paper we focus on the challenging problem of place categorization and semantic mapping on a robot with-out environment-specific training. Motivated by their ongoing success in various visual recognition tasks, we build our system upon a state-of-the-art convolutional network. We overcome its closed-set limitations by complementing the network with a series of one-vs-all classifiers that can learn to recognize new semantic classes online. Prior domain knowledge is incorporated by embedding the classification system into a Bayesian filter framework that also ensures temporal coherence. We evaluate the classification accuracy of the system on a robot that maps a variety of places on our campus in real-time. We show how semantic information can boost robotic object detection performance and how the semantic map can be used to modulate the robot’s behaviour during navigation tasks. The system is made available to the community as a ROS module.

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The problematic of invasive species in an alien environment has aroused the attention of scientists all over the world for quite some time. One of the exotic tree species that has provoked special attention in the tropical drylands is Prosopis juliflora. Originating in South America, prosopis (hereafter referred to as prosopis) has been introduced in the hot and semi-arid zones of the world particularly to provide fuelwood, to stabilize sand dunes and to combat desertification. The tree has become an essential source for fuelwood and a provider of several other products and services in areas where it has become established. However, despite the numerous benefits the tree provides to rural people, in several regions prosopis has become a noxious weed with a negative impact on the environment and to the economy of farmers and landowners. In India, prosopis was introduced in Andhra Pradesh in 1877. The tree was then proclaimed as the precious child of the plant world by scientists and local people alike. The purpose of this study was to investigate the overall impact of prosopis on local rural livelihoods in the drylands of South India. Of particular interest was the examination of the different usages of the tree, especially as fuelwood, and people s perceptions of it. Furthermore, the study examined the negative impacts of the uncontrolled invasion of prosopis on croplands, and its occupation of the banks of irrigation canals and other water sources. As another central theme, this study analysed the Hindu classification system for nature and for trees in particular. In India, several tree species are regarded as sacred. This study examined the position of the exotic prosopis among sacred trees, such as the bodhi, banyan and neem trees. The principle method for collecting the field data was by using individual and thematic group interviews. These interviews were semi-structured with open ended questions. Moreover, unstructured interviews as well as general observations provided complementary information. The data were gathered during two fieldwork periods in the states of Andhra Pradesh and Tamil Nadu, in South India. The results confirmed that prosopis both provides benefits and causes hazards to different stakeholders. Farmers and agriculturalists suffer economic losses in areas where prosopis has invaded crop fields and competes with other plants for water and nutrients. On the other hand, for a significant number of poor rural people, prosopis has become an important source of livelihood benefits. This tree, which grows on government wastelands, is commonly a free resource for all and has thus become a major local source of fuelwood. It also provides several other goods and services and cash income that contributes to improve livelihoods in rural communities. Prosopis ranked lowest in the tree classificatioin system of the Hindus of South India. Although it is appreciated for many benefits it provides for poor people, it has remained an outsider compared with the indigenous tree species. On the other hand, the most sacred trees, such as the bodhi or the banyan, are completely excluded from extraction and it is seen as a sacrilege to even cut branches from any of these trees. An unexpected finding was that, in a few cases, prosopis had also been elevated to the status of a sacred tree. Goods and services from prosopis are not utilized in the most beneficial way. Silvicultural management practices are suggested that would provide additional income and employment opportunities. Interventions are recommended to control further invasion of the tree that might cause serious negative effects in the future. For Hindus, the sacred always ranks highest, even above economic gain. The conservation of sacred groves and sacred trees is a tradition that has its roots in ancient history. These socio-religious practices need to be respected and continued. Successful management of tree and forest resources depends on the willingness of the local people to manage their natural resources, and this willingness exists and has always existed in South India. Keywords: South India, drylands, livelihood, fuelwood, invasive, resource, silviculture.

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A partir da Lei n. 6.938 de 31 de agosto de 1981, que constituiu o Sistema Nacional do Meio Ambiente, criou-se o Conselho Nacional do Meio Ambiente e instituiu-se o Cadastro Técnico Federal de Atividades e Instrumentos de Defesa Ambiental, a gestão ambiental pública ganhou um espaço cada vez maior nas administrações municipais, com a implementação de instrumentos de gestão ambiental propiciando aos municípios a possibilidade de ações efetivas que contribuam para uma melhor qualidade de vida a população. Esse trabalho propõe a criação de um método de classificação municipal que indicará qual o nível da gestão ambiental do município. Verificando o número de instrumentos de gestão ambiental constituído e o número de problemas ambientais ocorridos em cada município na visão do gestor local nos anos de 2006/2008. E ainda qual a influência do IDH tanto na implementação de tais instrumentos de gestão ambiental, como nas ocorrências dos problemas ambientais. Tal classificação tem a intenção de verificar se o município encontra-se bem aparelhado no que se refere à gestão ambiental, auxiliando para futuras decisões nas ações da política ambiental local. O foco desse trabalho serão os municípios dos estados de Minas Gerais, Piauí e Rio de Janeiro. Os resultados serão processados via o software MATLAB utilizando lógica nebulosa (fuzzy) e apresentados em um website utilizando as linguagens de programação JSP, HTML, JavaScript e esse website armazenado em um servidor TomCat e tais resultados serão apresentados nas formas de valores alfanuméricos em tabelas e espaciais através de mapas temáticos em uma solução sig-web. Os dados estão armazenados em um Sistema Gerenciador de Banco de Dados PostgreSQL com sua extensão espacial PostGIS, e o acesso aos mapas será feito através do servidor de mapas MapServer.

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This paper presents an account of some current uses of RIVPACS (River Invertebrate Prediction and Classification System), a software package developed by the Institute of Freshwater Ecology (UK). Background information is also given on the unique data-set on which the system is based. Before discussing RIVPACS, we consider the range of environmental stresses encountered in flowing-water systems and some of the ways in which stresses may affect macroinvertebrate communities. The wide application and relevance of the RIVPACS approach was recognised when it was chosen as the biological method for use throughout the UK in the 1990 River Quality Survey (RQS). In the concluding section we list some lessons learnt both from the 1990 survey and from our own testing exercise, and we outline current developments which will lead to a new version of RIVPACS for use in the 1995 RQS.

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RIVPACS (River InVertebrate Prediction And Classification System) is a software package developed by the Institute of Freshwater Ecology (IFE). The primary application is to assess the biological quality of rivers within the UK. RIVPACS offers site-specific predictions of the macroinvertebrate fauna to be expected in the absence of major environmental stress. The expected fauna is derived by RIVPACS using a small suite of environmental characteristics. The biological evaluation is then obtained by comparing the fauna observed at the site with the expected fauna. RIVPACS also includes a site classification based on the macroinvertebrate fauna of the component reference sites. New sites, judged by their fauna to be of high biological quality, may be allocated to classification groups within the fixed RIVPACS classification. This has potential for evaluating sites for conservation. In this chapter, the origins and history of the RIVPACS approach are described, including major scientific and operational developments over the life of the project. RIVPACS III is described in detail and predictions at different taxonomic levels are demonstrated. The value of the reference dataset for river management and conservation is examined, and the chapter concludes with a brief consideration of some future challenges.

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A presente pesquisa tem como objeto de estudo [re]conhecimento que os usuários de um hospital geral detêm sobre o trabalho do enfermeiro. Seu objetivo geral é discutir o entendimento dos usuários de um hospital geral do Rio de Janeiro sobre o trabalho do enfermeiro, à luz do seu reconhecimento profissional, e seus objetivos específicos são: identificar o [re]conhecimento que os usuários possuem sobre o trabalho do enfermeiro e analisar o [re]conhecimento dos usuários sobre o trabalho dos enfermeiros, buscando aproximações e distanciamentos das competências do enfermeiro. Esta pesquisa apoia-se nas concepções teóricas da psicodinâmica do trabalho desenvolvidas por Dejours, se apropriando mais profundamente, da discussão sobre a dinâmica do reconhecimento, na qual acredita que o reconhecimento pode ser um meio que possibilita a transformação do sofrimento no trabalho em prazer. Com o intuito de respeitar os princípios éticos e a Resolução 196/96, essa pesquisa foi encaminhada ao Comitê de Ética e Pesquisa com Seres Humanos/SR-2/UERJ e obteve parecer favorável com protocolo n 49.3.2012. Trata-se de um estudo exploratório-descritivo de abordagem quantitativa e desenho transversal. A população foram clientes internados nas enfermarias cirúrgicas e clínicas do referido hospital. Para melhor caracterizar o perfil da clientela internada foi utilizado o Sistema de Classificação de Pacientes elaborado por Perroca (1996) que baseia-se nas necessidades individualizadas de cuidado de enfermagem, com o intuito de identificar o grau de dependência que o sujeito apresenta da equipe de enfermagem. Os 65 participantes da pesquisa foram selecionados por meio de uma amostra intencional. O instrumento de coleta de dados utilizado foi um formulário contendo 22 perguntas, sendo 18 fechadas e 04 abertas. As informações foram coletadas no período de agosto a outubro de 2012 e analisadas utilizando-se da estatística descritiva simples. A apresentação dos dados foi através de tabelas e a sua discussão teve quatro tópicos, são eles: Perfil sociodemográfico da população; Experiências hospitalares anteriores; Conhecimento da população sobre o enfermeiro e o seu trabalho; O trabalho do enfermeiro e seu reconhecimento. Os resultados mostraram que o perfil sociodemográfico da população é composta por uma maioria feminina; a faixa etária predominante é de 55 a 64 anos e o grau de escolaridade da população é baixo. Para 75,4% dos sujeitos a atual internação hospitalar não é a primeira. No que se refere ao conhecimento que o participante tem sobre o enfermeiro, constatou-se que eles relatam saber quem é o profissional, qual é o seu grau de escolaridade, porém um número significativo não conhecia a composição da equipe de enfermagem (41,5%), demonstrando ser esse um fato contraditório. No que se refere ao reconhecimento conferido ao enfermeiro e seu trabalho, os participantes consideraram importante tanto o trabalho desenvolvido pelo enfermeiro, como também a sua atuação na equipe de saúde, e declararam a pouca valorização social que é imputada à profissão. As principais formas de reconhecimento atribuídas nesta pesquisa estavam relacionadas a sentimentos afetuosos positivos que a figura do enfermeiro gera e a excelência na prestação de cuidados de enfermagem.

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(1) A total of 45 sites was sampled, each being fished using the semi-quantitative and quantitative techniques. (2) A significant relationship existed between the semi-quantitative and Quantitative results for all age groups of salmonids (R2 83.4% to 96.1%, p < 0.0001). (3) The results from each site were categorised according to an existing classification system for quantitative and semi-quantitative data. The semi-quantitative component of this system was modified using the results of this investigation. The degree of error associated with sites classified semi-quantitatively was found to be slightly less when using the modified system for 0+ salmon, > 0+ salmon and 0+ trout, ranging from 10.5% to 30%. (4) Insufficient data points were available for the analysis of coarse fish data.

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Através do processamento de imagens digitais, mais especificamente as etapas de segmentação e classificação, foi possível analisar o processo de ocupação humana da bacia hidrográfica do rio Bonfim, localizada no município de Petrópolis, no estado do Rio de Janeiro. Este processo possibilitou a geração de mapas de uso da terra e cobertura vegetal e configurou-se numa importante etapa para avaliação ambiental capaz de auxiliar e dar fomento à execução de atividades de gestão e monitoramento do meio ambiente e de análise histórica dos remanescentes florestais ao longo dos últimos anos. Nesta pesquisa foram adotadas classes temáticas com o propósito de permitir a classificação das imagens digitais na escala 1/40.000. As classes adotadas foram: afloramento rochoso e vegetação rupestre; obras e edificações; áreas agrícolas e vegetação. Estudos foram feitos no sentido de indicar o melhor método de classificação. Primeiramente, efetuou-se a classificação no sistema SPRING, testando-se os melhores parâmetros de similaridade e área na detecção de fragmentos, somente da classe vegetação. Houve tentativa de classificar as demais classes de uso diretamente pelo sistema SPRING, mas esta classificação não foi viável por apresentar conflitos em relação às classes, desta forma, neste sistema foi feita somente a classificação e quantificação da classe vegetação. Visando dar continuidade a pesquisa, optou-se por executar uma interpretação visual, através do sistema ArcGis, para todas as classes de uso do solo, possibilitando o mapeamento da dinâmica de evolução humana, diante da floresta de mata atlântica na área de estudos e análise histórica de seus remanescentes entre os anos dos anos 1965, 1975, 1994 e 2006.

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Esta pesquisa refere-se ao desenvolvimento de um novo sistema triagem ou classificação de risco para os serviços de urgências e emergências pediátricas e ao estudo de validade e confiabilidade deste instrumento. O primeiro tópico trata de conceitos e fundamentos relacionados à triagem e evidencia a complexidade do tema em vários aspectos. O segundo tópico apresenta as justificativas para o desenvolvimento de um novo sistema de classificação de risco para o contexto de saúde brasileiro, diante das inadequações de se adotar sistemas idealizados em países com desenvolvimento econômico, social e cultural diversos. O terceiro tópico apresenta os objetivos da pesquisa: rever o estado da arte em relação à validade e confiabilidade de sistemas de triagem em crianças, descrever o desenvolvimento de um sistema brasileiro de classificação de risco para urgências e emergências pediátricas e estudar a validade e confiabilidade do novo instrumento. O quarto tópico é uma revisão sistemática da literatura sobre a validade e confiabilidade dos sistemas de triagem utilizados na população pediátrica. Localizaram-se estudos sobre sete sistemas de triagem desenvolvidos no Canadá, Reino Unido, EUA, Austrália, Escandinávia e África do Sul. Constatou-se a dificuldade de se comparar o desempenho de diferentes instrumentos, devido à heterogeneidade dos desfechos, das populações e dos contextos de saúde estudados. O quinto tópico descreve o processo de desenvolvimento de um instrumento brasileiro de classificação de risco em pediatria, CLARIPED, a partir do consenso entre especialistas e pré-testes. Justificou-se a escolha da Escala Sul Africana de Triagem como referência, pela sua simplicidade e objetividade e pela semelhança socioeconômica e demográfica entre os dois países. Introduziram-se várias modificações, mantendo-se a mesma logística do processo de triagem em duas etapas: aferição de parâmetros fisiológicos e verificação da presença de discriminadores de urgência. O sexto tópico se refere ao estudo prospectivo de validade e confiabilidade do CLARIPED no setor de emergência pediátrica de um hospital terciário brasileiro, no período de abril a julho de 2013. Uma boa validade de construto convergente foi confirmada pela associação entre os níveis de urgência atribuídos pelo CLARIPED e os desfechos evolutivos utilizados como proxies de urgência (utilização de recursos, hospitalização, admissão na sala de observação e tempo de permanência no setor de emergência). A comparação entre o CLARIPED e o padrão de referência mostrou boa sensibilidade de 0,89 (IC95%=0,78-0,95) e especificidade de 0,98 (IC95%=0,97-0,99) para diagnosticar elevada urgência. A confiabilidade interobservadores, resultou num kappa ponderado quadrático substancial de 0,75 (IC95%: 0,74-0,79). O sétimo e último tópico tece considerações finais sobre dois aspectos: a insuficiência de evidências científicas sobre os sistemas de triagem na população pediátrica e a oportunidade e relevância de se desenvolver um sistema brasileiro de classificação de risco para urgências e emergências pediátricas, válido e confiável, com possibilidades de adoção em âmbito nacional.

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A study was conducted, in association with the Alabama and Mississippi National Estuarine Research Reserves (NERRs) in the Gulf of Mexico (GoM) as well as the Georgia, South Carolina, and North Carolina NERRs in the Southeast (SE), to evaluate the impacts of coastal development on tidal creek sentinel habitats, including potential impacts to human health and well-being. Uplands associated with Southeast and Gulf of Mexico tidal creeks, and the salt marshes they drain, are popular locations for building homes, resorts, and recreational facilities because of the high quality of life and mild climate associated with these environments. Tidal creeks form part of the estuarine ecosystem characterized by high biological productivity, great ecological value, complex environmental gradients, and numerous interconnected processes. This research combined a watershed-level study integrating ecological, public health and human dimension attributes with watershed-level land cover data. The approach used for this research was based upon a comparative watershed and ecosystem approach that sampled tidal creek networks draining developed watersheds (e.g., suburban, urban, and industrial) as well as undeveloped sites (Holland et al. 2004, Sanger et al. 2008). The primary objective of this work was to define the relationships between coastal development with its concomitant land cover changes, and non-point source pollution loading and the ecological and human health and wellbeing status of tidal creek ecosystems. Nineteen tidal creek systems, located along the Southeastern United States coast from southern North Carolina to southern Georgia, and five Gulf of Mexico systems from Alabama and Mississippi were sampled during summer (June-August) 2005, 2006 (SE) and 2008 (GoM). Within each system, creeks were divided into two primary segments based upon tidal zoning: intertidal (i.e., shallow, narrow headwater sections) and subtidal (i.e., deeper and wider sections), and watersheds were delineated for each segment. In total, we report findings on 29 intertidal and 24 subtidal creeks. Indicators sampled throughout each creek included water quality (e.g., dissolved oxygen, salinity, nutrients, chlorophyll-a levels), sediment quality (e.g., characteristics, contaminant levels including emerging contaminants), pathogen and viral indicators (e.g., fecal coliform, enterococci, F+ coliphages, F- coliphages), and abundance and tissue contamination of biological resources (e.g., macrobenthic and nektonic communities, shellfish tissue contaminants). Tidal creeks have been identified as a sentinel habitat to assess the impacts of coastal development on estuarine areas in the southeastern US. A conceptual model for tidal creeks in the southeastern US identifies that human alterations (stressors) of upland in a watershed such as increased impervious cover will lead to changes in the physical and chemical environment such as microbial and nutrient pollution (exposures), of a receiving water body which then lead to changes in the living resources (responses). The overall objective of this study is to evaluate the applicability of the current tidal creek classification framework and conceptual model linking tidal creek ecological condition to potential impacts of development and urban growth on ecosystem value and function in the Gulf of Mexico US in collaboration with Gulf of Mexico NERR sites. The conceptual model was validated for the Gulf of Mexico US tidal creeks. The tidal creek classification system developed for the southeastern US could be applied to the Gulf of Mexico tidal creeks; however, some differences were found that warrant further examination. In particular, pollutants appeared to translate further downstream in the Gulf of Mexico US compared to the southeastern US. These differences are likely the result of the morphological and oceanographic differences between the two regions. Tidal creeks appear to serve as sentinel habitats to provide an early warning of the ensuing harm to the larger ecosystem in both the Southeastern and Gulf of Mexico US tidal creeks.

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Measuring capability variations within the population isanimportant process that can be used to support decision making regarding the inclusivity of design for all users, thus allowing the level of exclusion tobe defined veryearly and throughout the design process. Our hands often represent a central feature of the human-task interaction, and therefore, variations in the capabilities of the hands has the potential to exclude people from all or part of the tasks they perform. Data is presented from the performance of 15 people in one of three age groups (18-40, 41-64 and 65+). Using a classification system for defining hand actions the prevalence of different grips in response to a range of physical task demands was mapped in a way that allowed capability to be measured against other variables such as task quality. This was found toenhance thegranularity with which exclusion could be both measured and predicted.

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This thesis focuses on the modelling of settlement induced damage to masonry buildings. In densely populated areas, the need for new space is nowadays producing a rapid increment of underground excavations. Due to the construction of new metro lines, tunnelling activity in urban areas is growing. One of the consequences is a greater attention to the risk of damage on existing structures. Thus, the assessment of potential damage of surface buildings has become an essential stage in the excavation projects in urban areas (Chapter 1). The current damage risk assessment procedure is based on strong simplifications, which not always lead to conservative results. Object of this thesis is the development of an improved damage classification system, which takes into account the parameters influencing the structural response to settlement, like the non-linear behaviour of masonry and the soil-structure interaction. The methodology used in this research is based on experimental and numerical modelling. The design and execution of an experimental benchmark test representative of the problem allows to identify the principal factors and mechanisms involved. The numerical simulations enable to generalize the results to a broader range of physical scenarios. The methodological choice is based on a critical review of the currently available procedures for the assessment of settlement-induced building damage (Chapter 2). A new experimental test on a 1/10th masonry façade with a rubber base interface is specifically designed to investigate the effect of soil-structure interaction on the tunnelling-induced damage (Chapter 3). The experimental results are used to validate a 2D semi-coupled finite element model for the simulation of the structural response (Chapter 4). The numerical approach, which includes a continuum cracking model for the masonry and a non-linear interface to simulate the soil-structure interaction, is then used to perform a sensitivity study on the effect of openings, material properties, initial damage, initial conditions, normal and shear behaviour of the base interface and applied settlement profile (Chapter 5). The results assess quantitatively the major role played by the normal stiffness of the soil-structure interaction and by the material parameters defining the quasi-brittle masonry behaviour. The limitation of the 2D modelling approach in simulating the progressive 3D displacement field induced by the excavation and the consequent torsional response of the building are overcome by the development of a 3D coupled model of building, foundation, soil and tunnel (Chapter 6). Following the same method applied to the 2D semi-coupled approach, the 3D model is validated through comparison with the monitoring data of a literature case study. The model is then used to carry out a series of parametric analyses on geometrical factors: the aspect ratio of horizontal building dimensions with respect to the tunnel axis direction, the presence of adjacent structures and the position and alignment of the building with respect to the excavation (Chapter 7). The results show the governing effect of the 3D building response, proving the relevance of 3D modelling. Finally, the results from the 2D and 3D parametric analyses are used to set the framework of an overall damage model which correlates the analysed structural features with the risk for the building of being damaged by a certain settlement (Chapter 8). This research therefore provides an increased experimental and numerical understanding of the building response to excavation-induced settlements, and sets the basis for an operational tool for the risk assessment of structural damage (Chapter 9).

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The assessment of settlement induced damage on buildings during the preliminary phase of tunnel excavation projects, is nowadays receiving greater attention. Analyses at different levels of detail are performed on the surface building in proximity to the tunnel, to evaluate the risk of structural damage and the need of mitigation measures. In this paper, the possibility to define a correlation between the main parameters that influence the structural response to settlement and the potential damage is investigated through numerical analysis. The adopted 3D finite element model allows to take into account important features that are neglected in more simplified approaches, like the soil-structure interaction, the nonlinear behaviour of the building, the three dimensional effect of the tunnelling induced settlement trough and the influence of openings in the structure. Aim of this approach is the development of an improved classification system taking into account the intrinsic vulnerability of the structure, which could have a relevant effect on the final damage assessment. Parametric analyses are performed, focusing on the effect of the orientation and the position of the structure with respect to the tunnel. The obtained results in terms of damage are compared with the Building Risk Assessment (BRA) procedure. This method was developed by Geodata Engineering (GDE) on the basis of empirical observations and building monitoring and applied during the construction of different metro lines in urban environment. The comparison shows a substantial agreement between the two procedures on the influence of the analysed parameters. The finite element analyses suggest a refinement of the BRA procedure for pure sagging conditions.

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Underground constructions in soft ground may lead to settlement damage to existing buildings. In The Netherlands the situation is particularly complex, because of the combination of soft soil, fragile pile foundations and brittle, unreinforced masonry façades. The tunnelling design process in urban areas requires a reliable risk damage assessment. In the engineering practice the current preliminary damage assessment is based on the limiting tensile strain method (LTSM). Essentially this is an uncoupled analysis, in which the building is modelled as an elastic beam subject to imposed Greenfield settlements and the induced tensile strains are compared with a limit value for the material. The soil-structure interaction is included only as a ratio between the soil and the building stiffness. In this paper, a coupled approach is evaluated. The soil-structure interaction in terms of normal and shear behaviour is represented by interface elements and a cracking model for masonry is included. This project aims to improve the existing damage classification system for masonry buildings subjected to tunnel-induced settlement, in order to evaluate the necessity of strengthening techniques or mitigation measures.

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Settlements due to underground construction represent a risk for the architectural heritage, especially in The Netherlands, because of the combination of soft soil, fragile pile foundation and brittle, un-reinforced masonry façade. Modelling of soil-structure interaction is fundamental to assess the risk of building damage due to tunnelling. This paper presents results of finite element analyses carried out with different models for a simple masonry wall. Focus is paid on the comparison between coupled, uncoupled and semi-coupled analyses, in which the soil-structure interaction is represented in different ways. In particular, the implementation of a soil-structure interface model in the numerical analyses is analysed, in order to asses its validity. The aim of the research project is the development of a damage classification system for different building typologies.