Evidence for synaptotagmin as an inhibitory clamp on synaptic vesicle release in Aplysia neurons.

While previous studies have demonstrated that synaptotagmin plays an essential role in evoked neurotransmitter release, it has been difficult to determine whether it acts to facilitate or inhibit release. To address this question, we used acute genetic manipulations to alter the expression of synaptotagmin in Aplysia neurons. Transient overexpression of synaptotagmin in acutely dissected cholinergic neurons and in cultured glutaminergic neurons decreased the amplitude of the excitatory postsynaptic potential (EPSP) by 32% and 26%, respectively. In contrast, treatment of cultured presynaptic neurons with synaptotagmin antisense oligonucleotides increased the amplitude of the EPSP by 50-75%. These results are consistent with a role of synaptotagmin as an inhibitor of release.

Report on tests of welding filter plates /

Mode of access: Internet.

Evaluation of the usability and benefits of twist wire GMAW and FACW narrow gap welding /

"March 1988."

Welding and brazing : a literature search /

"Metallurgy and Ceramics."

Welding of thick plates of Bureau of Mines zirconium /

Work performed at the Battelle Memorial Institute, Columbus, Ohio.

Selected occupational fatalities related to welding and cutting as found in reports of OSHA facility/catastrophe investigations.

Shipping list no.: 88-705-P.

Welding, brazing, and thermal cutting.

Mode of access: Internet.

Welding, brazing, and thermal cutting.

Mode of access: Internet.

Welding safety.

Mode of access: Internet.

Welding and brazing : a bibliography of unclassified report literature.

Selected unclassified reports, supplementing those abstracted in TID-3059, which were available in TISE files on July 1, 1956, on welding and brazing of materials of interest to nuclear technology, such as Al, Be, Hf, Mo, Th, Ti, Zr, stainless steels, high-temperature alloys, pressure vessels, and heat exchangers, are annotated. Author, subject, and report number indexes are included. 127 references.

TIG welding for beginners.

Mode of access: Internet.

How to teach arc welding in farm mechanics.

Mode of access: Internet.