Premature suture closure and ectopic cranial bone in mice expressing Msx2 transgenes in the developing skull.

The coordinate growth of the brain and skull is achieved through a series of interactions between the developing brain, the growing bones of the skull, and the fibrous joints, or sutures, that unite the bones. These interactions couple the expansion of the brain to the growth of the bony plates at the sutures. Craniosynostosis, the premature fusion of the bones of the skull, is a common birth defect (1 in 3000 live births) that disrupts coordinate growth and often results in profoundly abnormal skull shape. Individuals affected with Boston-type craniosynostosis, an autosomal dominant disorder, bear a mutated copy of MSX2, a homeobox gene thought to function in tissue interactions. Here we show that expression of the mouse counterpart of this mutant gene in the developing skulls of transgenic mice causes craniosynostosis and ectopic cranial bone. These mice provide a transgenic model of craniosynostosis as well as a point of entry into the molecular mechanisms that coordinate the growth of the brain and skull.

Functional morphology and ontogeny of Keichousaurus hui (Reptilia, Sauropterygia) / Kebang Lin --, Olivier Rieppel --.

n.s. no.39(1998)

Phylogeny of the chelydrid turtles : a study of shared derived characters in the skull / Eugene S. Gaffney --.

v.33:no.9(1975)

A Wormian Bone, Mimicking an Entry Gunshot Wound of the Skull, in an Anthropological Specimen

Wormian bones (WB) are irregular small cranial ossicles found along suture lines and fontanels. In Brazil, gunshot wounds to the skull are quite common in young individuals. Nevertheless, as far as we know, this is the first report of a WB giving an erroneous aspect of gunshot entrance due to its displacement position. The present manuscript describes the case of a Brazilian young man who died due to ballistic trauma, where a gaping bony defect on the right side of the skull was thought to be the exit wound of an injury related to the destruction found on the left side, highly suggestive of firearm injury. Thus, this case study has brought to light similarities between a traumatic lesion and an orifice of a WB, with emphasis on differential diagnosis during routine anthropological examinations.

Morphometric measurements throughout ontogeny of selected planktic foraminiferal test species

Development plays an important part in shaping adult morphology and morphological disparity, yet its influence on evolutionary processes is seldom explored because of a lack of preservation of ontogenetic stages in the fossil record. By preserving their entire ontogenetic history within their test, and with the advent of high-resolution imaging techniques, planktic foraminifera allow us to investigate the influence of developmental constraints on disparity. Using Synchrotron radiation X-ray tomographic microscopy (SRXTM), we reconstruct the ontogenetic progression of seven species across several of the major morphotypic groups of planktic foraminifera, including morphotypes of a species exhibiting high phenotypic plasticity and closely related pseudo-cryptic sister-taxa. We show differences in growth patterns between the globigerinid species, which appear more tightly regulated within the framework of isometry from the neanic stage, and the globorotaliid species, whose adult stages present allometric trends. Morphological change through ontogeny results in a change in surface area to volume ratios. Different metabolic processes therefore dominate at different stages of ontogeny, changing the vulnerability of the organism to environmental influences over growth, from factors affecting diffusion rates in the juvenile to those affecting energy supply in the adult. These findings identify some of the parameters within which evolutionary mechanisms have to act.

A study of the effect of high yield criteria for emergency room skull radiography /

Mode of access: Internet.

The skull and dentition of a camel from the Pleistocene of Rancho La Brea,

Mode of access: Internet.

Wagon drilling in the Skull Creek area, Moffat County, Colorado /

"April, 1955."

The evolution of man; a popular exposition of the principal points of human ontogeny and phylogeny.

"Remarks and references to literature": vol. 2, p. [459]-490.

[Structure and development of the skull; a collection of pamphlets]

From the Philosophical transactions of the Royal society, 1866, 1869, 1871, 1873, 1874, 1876, 1878, 1881 and 1882.

Encephalomeningocele (protrusion of brain substance, covered with membranes, through a defect in the skull), drawn by Jean Young, ca. 1935

Carbon dust on Ross Stipple Board with water color added

The evolution of man : a popular exposition of the principal points of human ontogeny & phylogeny /

Bound in green publisher's cloth with gilt-stamped spine, blind-stamped boards, and yellow coated endpapers.

Stone age skull surgery: a general review, with emphasis on the New World.

"From the Smithsonian report for 1957."