Assessment of transferable competences in computing

The European Credit Transfer and Accumulation System (ECTS) is the credit system for higher education used in the European Higher Education Area (EHEA), which involves all the countries engaged in the Bologna Process. This paper describes a study which is part of the project of the Bologna Experts Team-Spain and was carried out with the following aims: 1) designing some procedures for the assessment of transferable competences; and 2) testing some basic psychometric features that an assessment device with some consequences for the subjects being evaluated needs to prove. We will focus on the degrees of Computing. The sample of students (20) includes first year students from the Technical University of Madrid. In this paper, we will report some results of data analyses carried out to this moment on reliability and validity of the task designed to measure problem solving.

Evaluación de competencias básicas en los grados de Informática de la UPM.

La evaluación de las competencias básicas tal y como se define en el RD 1393/2007, de 29 de octubre (BOE núm. 260, de 30 octubre 2007), por el que se establece la ordenación de las enseñanzas universitarias oficiales es una tarea que tendrán que abordar todas las universidades de cara a la posterior evaluación por la ANECA para mantener la acreditación de sus títulos de grado. En este trabajo se ilustra el protocolo que se ha diseñado y ejecutado para evaluar dichas competencias en los tres títulos de grado de la Universidad Politécnica de Madrid relacionados con la informática: Grado en Ingeniería de Computadores, Grado en Ingeniería del Software y Grado en Ingeniería Informática.

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β

Estrogen receptor (ER) modulators produce distinct tissue-specific biological effects, but within the confines of the established models of ER action it is difficult to understand why. Previous studies have suggested that there might be a relationship between ER structure and activity. Different ER modulators may induce conformational changes in the receptor that result in a specific biological activity. To investigate the possibility of modulator-specific conformational changes, we have applied affinity selection of peptides to identify binding surfaces that are exposed on the apo-ERs α and β and on each receptor complexed with estradiol or 4-OH tamoxifen. These peptides are sensitive probes of receptor conformation. We show here that ER ligands, known to produce distinct biological effects, induce distinct conformational changes in the receptors, providing a strong correlation between ER conformation and biological activity. Furthermore, the ability of some of the peptides to discriminate between different ER α and ER β ligand complexes suggests that the biological effects of ER agonists and antagonists acting through these receptors are likely to be different.

A deletion in an indole synthase gene is responsible for the DIMBOA-deficient phenotype of bxbx maize

The biosynthesis of DIMBOA, a pesticidal secondary metabolite of maize, branches off the tryptophan pathway. We have previously demonstrated that indole is the last intermediate common to both the tryptophan and hydroxamic acid pathways. The earliest discovered mutant in the DIMBOA pathway, bxbx (benzoxazineless), is deficient in the production of DIMBOA and related compounds. This paper presents evidence that a gene identified by Kramer and Koziel [Kramer, V. C. & Koziel, M. G. (1995) Plant Mol. Biol. 27, 1183–1188] as maize tryptophan synthase α (TSA) is the site of the genetic lesion in the DIMBOA-deficient mutant maize line bxbx. We demonstrate that the TSA gene has sustained a 924-bp deletion in bxbx compared with its counterpart in wild-type maize. We report that the TSA gene maps to the same location as the bxbx mutation, on the short arm of chromosome 4. We present evidence that the very early and very high level of expression of TSA corresponds to the timing and level of DIMBOA biosynthesis but is strikingly different from the expression of the maize tryptophan synthase β (TSB) genes. We show that feeding indole to bxbx seedlings restores their ability to synthesize DIMBOA. We conclude that the maize enzyme initially named tryptophan synthase α in fact is a DIMBOA biosynthetic enzyme, and we propose that it be renamed indole synthase. This work confirms and enlarges upon the findings of Frey et al. [Frey, M. Chomet, P., Glawischniq, E., Stettner, C., Grün, S., Winklmair, A., Eisenreich, W., Bacher, A., Meeley, R. B., Briggs, S. P., Simcox, K. & Gierl, A. (1997) Science 277, 696–699], which appeared while the present paper was in review.

Dated co-occurrence of Homo erectus and Gigantopithecus from Tham Khuyen Cave, Vietnam.

Tham Khuyen Cave (Lang Son Province, northern Vietnam) is one of the more significant sites to yield fossil vertebrates in east Asia. During the mid-1960s, excavation in a suite of deposits produced important hominoid dental remains of middle Pleistocene age. We undertake more rigorous analyses of these sediments to understand the fluvial dynamics of Pleistocene cave infilling as they determine how skeletal elements accumulate within Tham Khuyen and other east Asian sites. Uranium/thorium series analysis of speleothems brackets the Pleistocene chronology for breaching, infilling, and exhuming the regional paleokarst. Clast analysis indicates sedimentary constituents, including hominoid teeth and cranial fragments accumulated from very short distances and under low fluvial energy. Electron spin resonance analysis of vertebrate tooth enamel and sediments shows that the main fossil-bearing suite (S1-S3) was deposited about 475 thousand years ago. Among the hominoid teeth excavated from S1-S3, some represent Homo erectus and Gigantopithecus blacki. Criteria are defined to differentiate these teeth from more numerous Pongo pygmaeus elements. The dated co-occurrence of Homo erectus and Gigantopithecus blacki at Tham Khuyen helps to establish the long co-existence of these two species throughout east Asia during the Early and Middle Pleistocene.

Catharine Waugh McCullouch papers in the Mary Earhart Dillon collection, 1869-1945

Collection primarily documents McCulloch's research on women's legal status, and her work with the Illinois Equal Suffrage Association, the National American Woman Suffrage Association, and the League of Women Voters. There is also documentation of women in the legal profession, of McCulloch's friendships with the other women suffragists and lawyers, and some biographical material. The papers contain little information about her family or social life.

Address to the students, 1791 September 17

5-page handwritten copy of an address by Eliphalet Pearson made to Harvard students Bowman, Flagg, McKean, and Shaw reprimanding them for their "abusive treatment of the Junior class." The students are likely Thomas Bowman, Samuel Aldridge Flagg, and Joseph McKean, members of the Class of 1794, and Philander Shaw, member of the Class of 1792.

Neueste Karte der Koenigreiche Bosnien Servien Croatien und Slavonien: samt den angrœnzenden Provinzen Temeswar, Dalmatien, Herzegowina, Ragusa, Steyermark, Kærthen, Krain, Friaul, Gradiska, und Istrien, einem grossen Theil von Ungarn, Siebenbürgen, Walachei, Bulgarien, Albanien, Macedonien, und einem Stück des Kirchenstaats und K.reichs Neapel

nach den besten Originalzeichnungen Charten und Beschriebungen entworfen von Herrn Carl Schütz ; gestochen von C. Schütz und F. Müller.

Abañēễme : guía práctica para aprender el idioma guaraní = practical guide for learning the Guaraní tongue = praktischer Führer zur Erlernung des Guaraní.

Paged also in duplicate ([1], iv, iv, 74, 74 p.)

Ulysses' tale of wanderings; ballad version from Homer's Odyssey.

On spine: A tale of wanderings, by Isaac Flagg.

Symbol and satire in the French Revolution,

Mode of access: Internet.

The life and letters of Washington Allston,

Includes index.

Sämmtliche Werke /

Mode of access: Internet.